Congenital Hypothyroidism

Common Name(s)

Congenital Hypothyroidism

Congenital hypothyroidism is a condition that affects infants from birth and results from a partial or complete loss of thyroid function (hypothyroidism). The thyroid gland makes hormones that play an important role in regulating growth, brain development, and metabolism in the body. Congenital hypothyroidism occurs when the thyroid gland fails to develop or function properly. If untreated, congenital hypothyroidism can lead to intellectual disability and abnormal growth. In the United States and many other countries, all newborns are tested for congenital hypothyroidism. If treatment begins in the first month after birth, infants usually develop normally. Most cases of congenital hypothyroidism occur in people with no history of the disorder in their family; however, this condition can also be inherited.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital Hypothyroidism" for support, advocacy or research.

The MAGIC Foundation

The MAGIC Foundation Mission The MAGIC Foundation is a national non-profit organization created to provide support services for the families of children afflicted with a wide variety of chronic and/or critical disorders, syndromes and diseases that affect a child’s growth. Since its inception the Foundation has grown to include support services for adults who were also impacted by these disorders.

Last Updated: 7 Nov 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital Hypothyroidism" for support, advocacy or research.

The MAGIC Foundation

The MAGIC Foundation Mission The MAGIC Foundation is a national non-profit organization created to provide support services for the families of children afflicted with a wide variety of chronic and/or critical disorders, syndromes and diseases that affect a child’s growth. Since its inception the Foundation has grown to include support services for adults who were also impacted by these disorders.

http://www.magicfoundation.org

Last Updated: 7 Nov 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Congenital Hypothyroidism" returned 219 free, full-text research articles on human participants. First 3 results:

Monitoring and prognostic evaluation of patients with congenital hypothyroidism treated in a pediatric endocrinology unit.
 

Author(s): Tolga Unüvar, Korcan Demir, Ayhan Abacı, Ali Ataş, Atilla Büyükgebiz, Ece Böber

Journal: Turk. J. Pediatr.. ;55(4):384-90.

 

In this study, the etiological factors, diagnostic approaches, dose, and duration of treatment were compared between cases with transient and permanent congenital hypothyroidism (CH) with respect to prognosis. One hundred and twenty-two patients who received treatments with the diagnosis ...

Last Updated: 2 Dec 2013

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Children with congenital hypothyroidism have similar neuroradiological abnormal findings as healthy ones.
 

Author(s): Marianna Rachmiel, Susanne Blaser, Elysa Widjaja, Joanne Rovet

Journal:

 

To assess the neuroradiological findings of children with congenital hypothyroidism (CHT) compared to healthy controls (HC).

Last Updated: 13 Nov 2013

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Permanent and transient congenital hypothyroidism in Fayoum, Egypt: a descriptive retrospective study.
 

Author(s): Osama E M Bekhit, Remon M Yousef

Journal:

 

Congenital hypothyroidism (CH) is one of the most common preventable causes of mental retardation. One important challenge in understanding the epidemiology of CH is that some newborns will have transient CH, a temporary depression of thyroid hormone concentrations that can last from ...

Last Updated: 10 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Congenital Hypothyroidism" returned 15 free, full-text review articles on human participants. First 3 results:

Congenital hypothyroidism: recommendations of the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism.
 

Author(s): Léa Maria Zanini Maciel, Edna Teruko Kimura, Célia Regina Nogueira, Glaucia M F S Mazeto, Patrícia Künzle Ribeiro Magalhães, Marilza Leal Nascimento, Suzana Nesi-França, Sandra E Vieira,

Journal: Arq Bras Endocrinol Metabol. 2013 Apr;57(3):184-92.

 

Congenital hypothyroidism (CH) is the most common congenital endocrine disorder, with an incidence of 1:2,000 to 1:4,000 live births and it is a leading preventable mental retardation. Neonatal Screening Programs allow early identification of the disease and the adequate treatment ...

Last Updated: 17 May 2013

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Optimising outcome in congenital hypothyroidism; current opinions on best practice in initial assessment and subsequent management.
 

Author(s): Malcolm Donaldson, Jeremy Jones

Journal: J Clin Res Pediatr Endocrinol. 2013 ;5 Suppl 1():13-22.

 

Congenital hypothyroidism (CH), usually of the primary and permanent variety, is an eminently preventable cause of growth retardation and mental handicap whose outlook has been transformed by newborn screening, usually involving the measurement of capillary thyroid stimulating hormone ...

Last Updated: 4 Mar 2013

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Newborn screening for congenital hypothyroidism.
 

Author(s): Atilla Büyükgebiz

Journal: J Clin Res Pediatr Endocrinol. 2013 ;5 Suppl 1():8-12.

 

Newborn screening (NS) for congenital hypothyroidism (CH) is one of the major achievements in preventive medicine. Most neonates born with CH have normal appearance and no detectable physical signs. Hypothyroidism in the newborn period is almost always overlooked, and delayed diagnosis ...

Last Updated: 4 Mar 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.
 

Status: Recruiting

Condition Summary: Congenital Hypothyroidism

 

Last Updated: 28 Apr 2014

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The Prevalence of Hearing Loss Among Children With Congenital Hypothyroidism
 

Status: Recruiting

Condition Summary: Congenital Hypothyroidism; Hearing Loss

 

Last Updated: 18 Oct 2010

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Iodine Status in Pregnant Women and Their Newborns: is Congenital Hypothyroidism Related to Iodine Deficiency in Pregnancy?
 

Status: Recruiting

Condition Summary: Congenital Hypothyroidism; Pregnancy; Iodine Deficiency

 

Last Updated: 20 Jul 2007

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