Congenital human immunodeficiency virus

Common Name(s)

Congenital human immunodeficiency virus, Congenital HIV

Congenital HIV is an HIV infection present from birth. Most often an HIV positive mother passes HIV to her baby during delivery or through breast milk. HIV is a retrovirus which weakens the body’s defense or immune system and can develop into AIDS. It is transmitted through bodily fluids. A woman might not know if she is infected with HIV, so testing for HIV before or early in pregnancy is important. If the woman is HIV positive, special steps can be taken to decrease the risk that the virus passes to the baby from 15% to 1%.

Symptoms of congenital HIV may include frequent infections, persistent thrush, and unusual rashes. These happen because HIV attacks and damages T-cells, which are part of our immune system. This makes it harder for the body to fight off infection. HIV can also enter the central nervous system and brain which causes HIV encephalopathy. This may cause developmental delay (especially speech delay), behavior changes, and developmental regression. Babies with HIV are often slow to grow and gain weight. The heart, liver and spleen may be enlarged

In order to decrease the risk of transmission, an HIV positive women’s doctor or midwife will recommend taking antiretroviral medication during the pregnancy. A C-section is also recommended. Breastfeeding should be avoided if possible. After birth, the baby should also be on antiretroviral medication for about a month. If your baby does have congenital HIV, he or she will need lifelong treatment with these medications. Many babies are screened for congenital HIV at birth so that treatment may begin early, but the conditions included in newborn screening vary by state. For more information, visit Baby’s First Test. If your baby has congenital HIV, talk with your doctor about the most current treatment options. Support groups are also a good source of informati

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital human immunodeficiency virus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital human immunodeficiency virus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Congenital human immunodeficiency virus" returned 6 free, full-text research articles on human participants. First 3 results:

Congenital toxoplasmosis transmitted by human immunodeficiency-virus infected women.
 

Author(s): Kátia Martins Lopes de Azevedo, Sérgio Setúbal, Vania Gloria Silami Lopes, Luiz Antônio Bastos Camacho, Solange Artimos de Oliveira

Journal: Braz J Infect Dis. ;14(2):186-9.

 

We report the occurrence of congenital toxoplasmosis in three infants born to HIV infected women who had high anti-toxoplasma IgG and negative IgM during pregnancy. We briefly reviewed available literature and discussed the possible transmission mechanisms of congenital toxoplasmosis ...

Last Updated: 21 Jun 2010

Go To URL
Prevalence of congenital cardiovascular malformations in children of human immunodeficiency virus-infected women: the prospective P2C2 HIV Multicenter Study. P2C2 HIV Study Group, National Heart, Lung, and Blood Institute, Bethesda, Maryland.
 

Author(s): W W Lai, S E Lipshultz, K A Easley, T J Starc, S E Drant, J T Bricker, S D Colan, D S Moodie, G Sopko, S Kaplan

Journal: J. Am. Coll. Cardiol.. 1998 Nov;32(6):1749-55.

 

The purpose of the study was to assess the effects of maternal HIV-1 (human immunodeficiency virus) infection and vertically transmitted HIV-1 infection on the prevalence of congenital cardiovascular malformations in children.

Last Updated: 16 Dec 1998

Go To URL
Effect of low- and intermediate-purity clotting factor therapy on progression of human immunodeficiency virus infection in congenital clotting disorders. Transfusion Safety Study Group.
 

Author(s): G F Gjerset, M C Pike, J W Mosley, J Hassett, M A Fletcher, E Donegan, J W Parker, R B Counts, Y Zhou, C K Kasper

Journal: Blood. 1994 Sep;84(5):1666-71.

 

Low- and intermediate-purity clotting-factor therapies are believed to accelerate human immunodeficiency virus (HIV) progression in hemophiliacs through adverse immune effects of the other plasma proteins in the preparations. To investigate this postulate, we evaluated data from six ...

Last Updated: 28 Sep 1994

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Congenital human immunodeficiency virus" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease
 

Status: Recruiting

Condition Summary: Bone Marrow Failure Syndrome; Severe Aplastic Anemia; Severe Congenital Neutropenia; Amegakaryocytic Thrombocytopenia; Diamond-Blackfan Anemia; Schwachman Diamond Syndrome; Primary Immunodeficiency Syndromes; Acquired Immunodeficiency Syndromes; Histiocytic Syndrome; Familial Hemophagocytic Lymphocytosis; Lymphohistiocytosis; Macrophage Activation Syndrome; Langerhans Cell Histiocytosis (LCH); Hemoglobinopathies; Sickle Cell Disease; Sickle Cell-beta-thalassemia

 

Last Updated: 30 Mar 2015

Go to URL
CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia (CML); Acute Myelogenous Leukemia (AML);; Myelodysplastic Syndrome (MDS);; Juvenile Myelomonocytic Leukemia (JMML);; Acute Lymphoblastic Leukemia (ALL);; Lymphoma (Hodgkin's and Non-Hodgkin's)

 

Last Updated: 26 Mar 2015

Go to URL