Congenital Heart Block

Common Name(s)

Congenital Heart Block

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital Heart Block" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Congenital Heart Block" returned 90 free, full-text research articles on human participants. First 3 results:

Towards computational modelling of the human foetal electrocardiogram: normal sinus rhythm and congenital heart block.
 

Author(s): Eleftheria Pervolaraki, Sam Hodgson, Arun V Holden, Alan P Benson

Journal: Europace. 2014 May;16(5):758-65.

 

We aim to engineer a computational model of propagation during normal sinus rhythm in the foetal human heart, by modifying models for adult cardiac tissue to match foetal electrocardiogram (fECG) characteristics. The model will be partially validated by fECG data, and applied to explore ...

Last Updated: 6 May 2014

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Anaesthetic management of a premature low-birth-weight neonate with congenital complete heart block for implantation of temporary epicardial pacing wires.
 

Author(s): Oriana Ng, Shahani Jagdish Shahani

Journal: Singapore Med J. 2014 Jan;55(1):e9-11.

 

The optimal anaesthetic management of neonates with complete congenital heart block (CCHB) is unknown, as there is a low incidence of such cases. Neonates with CCHB often require surgery for the initiation of electronic pacing. In addition to the challenges of anaesthetising a neonate, ...

Last Updated: 23 Jan 2014

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Congenital heart block maternal sera autoantibodies target an extracellular epitope on the α1G T-type calcium channel in human fetal hearts.
 

Author(s): Linn S Strandberg, Xuezhi Cui, Arianna Rath, Jie Liu, Earl D Silverman, Xiaoru Liu, Vinayakumar Siragam, Cameron Ackerley, Brenda Bin Su, Jane Yuqing Yan, Marco Capecchi, Luca Biavati, Alice Accorroni, William Yuen, Filippo Quattrone, Kalvin Lung, Edgar T Jaeggi, Peter H Backx, Charles M Deber, Robert M Hamilton

Journal:

 

Congenital heart block (CHB) is a transplacentally acquired autoimmune disease associated with anti-Ro/SSA and anti-La/SSB maternal autoantibodies and is characterized primarily by atrioventricular (AV) block of the fetal heart. This study aims to investigate whether the T-type calcium ...

Last Updated: 16 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Congenital Heart Block" returned 8 free, full-text review articles on human participants. First 3 results:

Neonatal congenital heart block.
 

Author(s): Ayse Yildirim, F Sedef Tunaoolu, Aysu Turkmen Karaaoac

Journal: Indian Pediatr. 2013 May;50(5):483-8.

 

Congenital Heart Block (CHB) is the most serious complication of neonatal lupus erythematosus. Transplasental transfer of maternal anti SSA/Ro or antiSSB/La antibodies around 12th week of gestation is associated with development of CHB. This may lead to inflammation, fibrosis and ...

Last Updated: 19 Jun 2013

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Congenital heart block: evidence for a pathogenic role of maternal autoantibodies.
 

Author(s): Aurélie Ambrosi, Marie Wahren-Herlenius

Journal:

 

During pregnancy in autoimmune conditions, maternal autoantibodies are transported across the placenta and may affect the developing fetus. Congenital heart block (CHB) is known to associate with the presence of anti-Ro/SSA and anti-La/SSB antibodies in the mother and is characterized ...

Last Updated: 18 Sep 2012

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Cardiac manifestations of neonatal lupus: a review of autoantibody-associated congenital heart block and its impact in an adult population.
 

Author(s): Christine Capone, Jill P Buyon, Deborah M Friedman, William H Frishman

Journal: Cardiol Rev. ;20(2):72-6.

 

Within the last decade the prevalence of adult patients living with congenital heart disease equals that seen in children. This expanding population poses a challenge to clinical cardiologists who will be caring for patients with the clinical manifestations of this condition. Neonatal ...

Last Updated: 8 Feb 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Preventive Approach to Congenital Heart Block With Hydroxychloroquine
 

Status: Recruiting

Condition Summary: Congenital Heart Block; Neonatal Lupus; Autoantibody-Associated Heart Block

 

Last Updated: 7 Jun 2013

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The Research Registry for Neonatal Lupus
 

Status: Recruiting

Condition Summary: Neonatal Lupus; Systemic Lupus Erythematosus; Sjogren's Syndrome; Congenital Heart Block

 

Last Updated: 9 Apr 2013

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Last Updated: 12 Sep 2005

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