Acute Disseminated Encephalomyelitis

Common Name(s)

Acute Disseminated Encephalomyelitis

Acute disseminated encephalomyelitis (ADEM) is a neurological condition characterized by a brief but intense attack of inflammation in the brain and spinal cord that damages myelin Ð the protective covering of nerve fibers.  It often follows viral infection, or less often, vaccination for measles, mumps, or rubella. Treatment for ADEM is targeted at suppressing inflammation in the brain using anti-inflammatory drugs. Plasmapheresis or intravenous immunoglobulin therapy may also be used.  Additional treatment is symptomatic and supportive.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acute Disseminated Encephalomyelitis" for support, advocacy or research.

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

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The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acute Disseminated Encephalomyelitis" for support, advocacy or research.

Logo
Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

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The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acute Disseminated Encephalomyelitis" returned 126 free, full-text research articles on human participants. First 3 results:

[Severe acute disseminated encephalomyelitis associated with parainfluenza 3 infection: Case report].
 

Author(s): Felipe Olivares, Marcia Salinas, Andrés Soto, Jeannette Dabanch, Alberto Fica

Journal: Rev Chilena Infectol. 2015 Aug;32(4):476-81.

 

Disseminated encephalomyelitis (ADEM) is an infrequent condition with considerable morbidity and mortality in adult patients. It requires a high level of suspicion and diagnosis emerges by gathering clinical information, laboratory exams and images studies. ADEM is related to an immunological ...

Last Updated: 6 Oct 2015

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Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report.
 

Author(s): Solange Dourado de Andrade, Maria Graciede Filha Santarém Andrade, Pablo José Santos, Maria de Lourdes Galvão, Mariana Martins de Barros, Rajendranath Ramasawmy, Izabella Picinin Safe, Wuelton Marcelo Monteiro, Meritxell Sabidó, Maria das Graças Costa Alecrim

Journal: Rev. Soc. Bras. Med. Trop.. ;48(4):498-500.

 

Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. ...

Last Updated: 28 Aug 2015

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Outcome of children with acute disseminated encephalomyelitis in a tertiary care center in India.
 

Author(s): Gurdeep S Dhooria, Harmesh S Bains, Deepak Bhat, Shalini Wats

Journal: Turk. J. Pediatr.. ;56(5):507-10.

 

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disease of the brain that follows viral infection or vaccination, or even appears spontaneously. The objective of the study was to evaluate the clinical, neuroimaging and laboratory profiles of children with ADEM. Seventeen ...

Last Updated: 29 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acute Disseminated Encephalomyelitis" returned 8 free, full-text review articles on human participants. First 3 results:

Acute disseminated encephalomyelitis as the first presentation of CNS tuberculosis: report of a case with brief review.
 

Author(s): Ibrahim Masoodi, Omar Farooq, Iqbal Ahmad, Mohammad Yaseen Bhat, Nazir Ahmad, Hamid-ullah Wani, Javeed Ahmad Dar

Journal:

 

Acute disseminated encephalomyelitis (ADEM) also known as post infectious encephalomyelitis is a demyelinating disease of the central nervous system (CNS) that typically presents as a monophasic disorder associated with multifocal neurological symptoms and disability. It may follow ...

Last Updated: 8 Dec 2010

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Small cell lung carcinoma presenting with acute disseminated encephalomyelitis.
 

Author(s): R Summerfield, A Al-Saleh, S E Robbins

Journal: Br J Radiol. 2010 Mar;83(987):e54-7.

 

Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease characterised by subcortical high-signal white matter lesions on T2 weighted MRI. It most commonly occurs in children following an acute viral illness. We present a case study in which ADEM was the presenting condition ...

Last Updated: 3 Mar 2010

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Acute disseminated encephalomyelitis and multiple sclerosis.
 

Author(s): Hans Lassmann

Journal: Brain. 2010 Feb;133(Pt 2):317-9.

 

Last Updated: 17 Feb 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.