Congenital Disorder of Glycosylation

Common Name(s)

Congenital Disorder of Glycosylation, Congenital disorders of glycosylation, Carbohydrate Deficient Glycoprotein Syndrome

Congenital disorders of glycosylation (CDG) are a group of inherited metabolic disorders that affect a process called glycosylation. Glycosylation is the complex process by which all human cells build long sugar chains that are attached to proteins, which are called glycoproteins. There are many steps involved in this process, and each step is triggered by a type of protein called an enzyme. Individuals with a CDG are missing one of the enzymes that is required for glycosylation. The type of CDG that a person has depends on which enzyme is missing. Currently, there are 19 identified types of CDG.  CDG type IA is the most common form. The symptoms of CDG vary widely among affected individuals. Some people have severe developmental delay, failure to thrive, and multiple organ problems, while others have diarrhea, low blood sugar (hypoglycemia), liver problems, and normal developmental potential.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital Disorder of Glycosylation" for support, advocacy or research.

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CDG Family Network

Our mission is to exchange information about CDG with families and physicians, to locate new families, to raise awareness among the medical community and general public, and to encourage medical research.

Last Updated: 10 May 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Congenital Disorder of Glycosylation" for support, advocacy or research.

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CDG Family Network

Our mission is to exchange information about CDG with families and physicians, to locate new families, to raise awareness among the medical community and general public, and to encourage medical research.

http://www.cdgs.com

Last Updated: 10 May 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Congenital Disorder of Glycosylation" returned 0 free, full-text research articles on human participants.

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Congenital Disorder of Glycosylation" returned 0 free, full-text review articles on human participants.

 
 
 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
 

Status: Recruiting

Condition Summary: Congenital Disorders of Glycosylation

 

Last Updated: 13 May 2014

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