Actinic Cheilitis

Common Name(s)

Actinic Cheilitis

Actinic Cheilitis, also known as “sailor’s lip” is a condition that affects the skin surrounding the lips. Although the precise cause of this disorder is not fully understood, increased exposure to the sun, poor fitting dentures, and bad oral hygiene are considered risk factors for this condition. Actinic cheilitis may cause various symptoms involving irritation of the lips, scaley skin, swelling, and a thickening of the border between the lips and the skin. In addition, the affected area may become cancerous in about 10% of the cases. Actinic cheilitis is typically diagnosed by a physician with a physical exam. Treatment for actinic cheilitis include surgical techniques that aim to remove the damaged skin so that new, healthy skin can grow in the area, and medicine that stops damaged DNA from being made. Treatments are rapidly progressing with advances in medical research.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Actinic Cheilitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Actinic Cheilitis" returned 18 free, full-text research articles on human participants. First 3 results:

Immunohistochemical expression of matrix metalloproteinase-1, matrix metalloproteinase-2 and matrix metalloproteinase-9, myofibroblasts and Ki-67 in actinic cheilitis and lip squamous cell carcinoma.
 

Author(s): Bianca C Bianco, Fernanda M Scotti, Daniella S C Vieira, Michelle T Biz, Renata G Castro, Filipe Modolo

Journal: Int J Exp Pathol. 2015 Oct;96(5):311-8.

 

Matrix metalloproteinases (MMPs), myofibroblasts (MFs) and epithelial proliferation have key roles in neoplastic progression. In this study immunoexpression of MMP-1, MMP-2 and MMP-9, presence of MFs and the epithelial proliferation index were investigated in actinic cheilitis (AC), ...

Last Updated: 15 Jan 2016

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Clinicopathological profile and management of 161 cases of actinic cheilitis.
 

Author(s): Maria Luiza Diniz de Sousa Lopes, Francisco Leonardo da Silva Júnior, Kenio Costa Lima, Patrícia Teixeira de Oliveira, Éricka Janine Dantas da Silveira

Journal: An Bras Dermatol. ;90(4):505-12.

 

Actinic cheilitis (AC) is a potentially malignant disorder of the lip caused by chronic exposure to ultraviolet radiation from the sun.

Last Updated: 17 Sep 2015

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Value of videoroscopy in the detection of alterations of actinic cheilitis and the selection of biopsy areas.
 

Author(s): Ana-Maria Miranda, Thiago Ferrari, Taiana Leite, Tabata Domingos, Karin Cunha, Eliane Dias

Journal:

 

To demonstrate the value of videoroscopy in identifying lesions and alterations not seen by oroscopy and to select the area for biopsy.

Last Updated: 2 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Actinic Cheilitis" returned 1 free, full-text review articles on human participants. First 3 results:

Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects.
 

Author(s): Renata Aparecida Martinez Antunes Ribeiro Vieira, Eliana Maria Minicucci, Mariangela Esther Alencar Marques, Silvio Alencar Marques

Journal: An Bras Dermatol. ;87(1):105-14.

 

Actinic cheilitis is the main precancerous lesion of the lip. Squamous cell carcinoma of the lip is reported together with oral carcinomas in the Brazilian official statistics. Overall, they account for 40% of the head and neck carcinomas. In general, physicians and dentists know ...

Last Updated: 6 Apr 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Photodynamic Therapy (PDT) With Levulan and Blue Light for the Treatment of Actinic Cheilitis
 

Status: Not yet recruiting

Condition Summary: Actinic Cheilitis

 

Last Updated: 6 Apr 2015

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