Colorectal Cancer

Common Name(s)

Colorectal Cancer, Cancer, Colorectal

Colorectal cancer is cancer of the colon or rectum. The colon and the rectum are part of the large intestine, which is part of the digestive system. Colorectal cancer occurs when tumors form in the lining of the large intestine, also called the large bowel. Symptoms include diarrhea or constipation, blood in your stool, frequent gas pains or cramps, weight loss, fatigue, and nausea. Screening tests are important as these symptoms may not be present at first. Tests include colonoscopy and tests for blood in the stool.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Colorectal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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C3: Colorectal Cancer Coalition

Fight Colorectal Cancer ( formerly C3: Colorectal Cancer Coalition ) is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

Last Updated: 16 Oct 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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Colon Cancer Alliance

Our mission is to knock colon cancer out of the top three cancer killers. We are doing this by championing prevention, funding cutting-edge research and providing the highest quality patient support services.

Last Updated: 12 Oct 2013

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Colorectal Cancer Association of Canada

Our mandate is threefold: 1) To raise awareness of colorectal cancer, to educate the public about this disease, and how to prevent and treat it; 2) To provide support for colorectal cancer patients and their families; and 3) To advocate on their behalf for equal and timely access to effective medicines and treatments.

Last Updated: 9 Jul 2013

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Fight Colorectal Cancer

Fight Colorectal Cancer is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

Last Updated: 8 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Colorectal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

View Details
C3: Colorectal Cancer Coalition

Fight Colorectal Cancer ( formerly C3: Colorectal Cancer Coalition ) is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

http://www.fightcolorectalcancer.org

Last Updated: 16 Oct 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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Colon Cancer Alliance

Our mission is to knock colon cancer out of the top three cancer killers. We are doing this by championing prevention, funding cutting-edge research and providing the highest quality patient support services.

http://www.ccalliance.org

Last Updated: 12 Oct 2013

View Details
Colorectal Cancer Association of Canada

Our mandate is threefold: 1) To raise awareness of colorectal cancer, to educate the public about this disease, and how to prevent and treat it; 2) To provide support for colorectal cancer patients and their families; and 3) To advocate on their behalf for equal and timely access to effective medicines and treatments.

http://www.colorectal-cancer.ca

Last Updated: 9 Jul 2013

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Fight Colorectal Cancer

Fight Colorectal Cancer is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

http://fightcolorectalcancer.org

Last Updated: 8 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

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General Support Organizations

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General Resources

Research

We work with the gastrointestinal research community to identify emerging areas of study that should be explored. Once they are identified, Fight Colorectal Cancer helps build bridges between basic scientists, clinical researchers and patient advocates. Grant applications are peer-reviewed in collaboration with the American Association for Cancer Research, and target promising research for patients with metastatic colorectal cancer.

Updated 16 Oct 2012

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One Million Strong

Inspired by more than one million colorectal cancer survivors in the United States, Fight Colorectal Cancer has launched a national awareness campaign called One Million Strong to raise awareness and take action! We want to unify survivors and those

Updated 7 Mar 2013

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Blogs

Policy News

Blogs related to industry related items in the news.

Updated 16 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Colorectal Cancer" returned 11259 free, full-text research articles on human participants. First 3 results:

Breast and Colorectal Cancer Survival Disparities in Southeastern Wisconsin.
 

Author(s): Kirsten M M Beyer, Yuhong Zhou, Kevin Matthews, Kelly Hoormann, Amin Bemanian, Purushottam W Laud, Ann B Nattinger

Journal: WMJ. 2016 Feb;115(1):17-21.

 

Cancer health disparities by race, ethnicity, socioeconomic status, and geography are a top public health priority. Breast and colorectal cancer, in particular, have been shown to exhibit significant disparities and contribute a large proportion of morbidity and mortality from cancer. ...

Last Updated: 8 Apr 2016

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Colorectal cancer detection in an asymptomatic population: fecal immunochemical test for hemoglobin vs. fecal M2-type pyruvate kinase.
 

Author(s): Gian Paolo Caviglia, Luca Cabianca, Sharmila Fagoonee, Fabrizio M Gili

Journal: Biochem Med (Zagreb). 2016 ;26(1):114-20.

 

Screening programs for colorectal cancer (CRC) are mainly based on a first-line fecal immunochemical test for hemoglobin (FIT). Fecal M2-type pyruvate kinase (M2-PK) has been evaluated in clinical settings showing promising results for early CRC detection. However, the impact of fecal ...

Last Updated: 16 Mar 2016

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TNM Staging of Colorectal Cancer Should be Reconsidered According to Weighting of the T Stage: Verification Based on a 25-Year Follow-Up.
 

Author(s): Jun Li, Cheng-Hao Yi, Ye-Ting Hu, Jin-Song Li, Ying Yuan, Su-Zhan Zhang, Shu Zheng, Ke-Feng Ding

Journal: Medicine (Baltimore). 2016 Feb;95(6):e2711.

 

The gradient monotonicity of existing tumor, node, metastases staging systems for colorectal cancer is unsatisfactory. Our proposed T-plus staging system strengthens weighting of the T stage. In this study, applicability of the T-plus staging system was verified with data of a Chinese ...

Last Updated: 13 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Colorectal Cancer" returned 1204 free, full-text review articles on human participants. First 3 results:

Different definitions of CpG island methylator phenotype and outcomes of colorectal cancer: a systematic review.
 

Author(s): Min Jia, Xu Gao, Yan Zhang, Michael Hoffmeister, Hermann Brenner

Journal:

 

Contradictory results were reported for the prognostic role of CpG island methylator phenotype (CIMP) among colorectal cancer (CRC) patients. Differences in the definitions of CIMP were the most common explanation for these discrepancies. The aim of this systematic review was to give ...

Last Updated: 4 Mar 2016

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The Diagnostic Performance of Stool DNA Testing for Colorectal Cancer: A Systematic Review and Meta-Analysis.
 

Author(s): Rong-Lin Zhai, Fei Xu, Pei Zhang, Wan-Li Zhang, Hui Wang, Ji-Liang Wang, Kai-Lin Cai, Yue-Ping Long, Xiao-Ming Lu, Kai-Xiong Tao, Guo-Bin Wang

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2129.

 

This meta-analysis was designed to evaluate the diagnostic performance of stool DNA testing for colorectal cancer (CRC) and compare the performance between single-gene and multiple-gene tests.MEDLINE, Cochrane, EMBASE databases were searched using keywords colorectal cancers, stool/fecal, ...

Last Updated: 5 Feb 2016

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Neoadjuvant Treatment for Surgically Resectable Metastatic Colorectal Cancer.
 

Author(s): Marwan Al-Hajeili, John L Marshall, Brandon G Smaglo

Journal: Oncology (Williston Park, N.Y.). 2016 Jan;30(1):10-6.

 

The curative surgical resection of metastatic disease in patients with stage IV colorectal cancer with a limited tumor burden is standard of care. However, the role for neoadjuvant medical therapy and the ideal composition of that therapy are not established. Several neoadjuvant medical ...

Last Updated: 21 Jan 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Famitinib in Patients With Advanced Colorectal Cancer
 

Status: Recruiting

Condition Summary: Colorectal Cancer; Colorectal Cancer Metastatic; Colorectal Cancer Recurrent

 

Last Updated: 4 Jan 2013

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Abscopal Effect for Metastatic Colorectal Cancer
 

Status: Not yet recruiting

Condition Summary: Colorectal Cancer; Metastatic Colorectal Cancer; Thymalfasin

 

Last Updated: 28 Aug 2015

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Survivorship Care Plan in Promoting Physical Activity in Breast or Colorectal Cancer Survivors in Wisconsin
 

Status: Recruiting

Condition Summary: Cancer Survivor; Healthy Subject; Stage I Colorectal Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage IIA Breast Cancer; Stage IIA Colorectal Cancer; Stage IIB Breast Cancer; Stage IIB Colorectal Cancer; Stage IIC Colorectal Cancer; Stage IIIA Breast Cancer; Stage IIIA Colorectal Cancer; Stage IIIB Breast Cancer; Stage IIIB Colorectal Cancer; Stage IIIC Breast Cancer; Stage IIIC Colorectal Cancer

 

Last Updated: 18 Feb 2016

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