Colorectal Cancer

Common Name(s)

Colorectal Cancer, Cancer, Colorectal

Colorectal cancer is cancer of the colon or rectum. The colon and the rectum are part of the large intestine, which is part of the digestive system. Colorectal cancer occurs when tumors form in the lining of the large intestine, also called the large bowel. Symptoms include diarrhea or constipation, blood in your stool, frequent gas pains or cramps, weight loss, fatigue, and nausea. Screening tests are important as these symptoms may not be present at first. Tests include colonoscopy and tests for blood in the stool.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Colorectal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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C3: Colorectal Cancer Coalition

Fight Colorectal Cancer ( formerly C3: Colorectal Cancer Coalition ) is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

Last Updated: 16 Oct 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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Colon Cancer Alliance

Our mission is to knock colon cancer out of the top three cancer killers. We are doing this by championing prevention, funding cutting-edge research and providing the highest quality patient support services.

Last Updated: 12 Oct 2013

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Colorectal Cancer Association of Canada

Our mandate is threefold: 1) To raise awareness of colorectal cancer, to educate the public about this disease, and how to prevent and treat it; 2) To provide support for colorectal cancer patients and their families; and 3) To advocate on their behalf for equal and timely access to effective medicines and treatments.

Last Updated: 9 Jul 2013

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Fight Colorectal Cancer

Fight Colorectal Cancer is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

Last Updated: 8 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Colorectal Cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

View Details
C3: Colorectal Cancer Coalition

Fight Colorectal Cancer ( formerly C3: Colorectal Cancer Coalition ) is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

http://www.fightcolorectalcancer.org

Last Updated: 16 Oct 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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Colon Cancer Alliance

Our mission is to knock colon cancer out of the top three cancer killers. We are doing this by championing prevention, funding cutting-edge research and providing the highest quality patient support services.

http://www.ccalliance.org

Last Updated: 12 Oct 2013

View Details
Colorectal Cancer Association of Canada

Our mandate is threefold: 1) To raise awareness of colorectal cancer, to educate the public about this disease, and how to prevent and treat it; 2) To provide support for colorectal cancer patients and their families; and 3) To advocate on their behalf for equal and timely access to effective medicines and treatments.

http://www.colorectal-cancer.ca

Last Updated: 9 Jul 2013

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Fight Colorectal Cancer

Fight Colorectal Cancer is a national, nonpartisan organization whose mission is to win the fight against colorectal cancer through research, empowerment and access. FightCRC pushes for research to improve screening, diagnosis, and treatment of colorectal cancer; for policy decisions that make the most effective colon and rectal cancer prevention and treatment available to all; and for increased awareness that colorectal cancer is preventable, treatable, and beatable.

http://fightcolorectalcancer.org

Last Updated: 8 Apr 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

View Details
Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

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General Support Organizations

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General Resources

Research

We work with the gastrointestinal research community to identify emerging areas of study that should be explored. Once they are identified, Fight Colorectal Cancer helps build bridges between basic scientists, clinical researchers and patient advocates. Grant applications are peer-reviewed in collaboration with the American Association for Cancer Research, and target promising research for patients with metastatic colorectal cancer.

Updated 16 Oct 2012

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One Million Strong

Inspired by more than one million colorectal cancer survivors in the United States, Fight Colorectal Cancer has launched a national awareness campaign called One Million Strong to raise awareness and take action! We want to unify survivors and those

Updated 7 Mar 2013

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Blogs

Policy News

Blogs related to industry related items in the news.

Updated 16 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Colorectal Cancer" returned 13363 free, full-text research articles on human participants. First 3 results:

Down-Regulation of MicroRNA-214 Contributed to the Enhanced Mitochondrial Transcription Factor A and Inhibited Proliferation of Colorectal Cancer Cells.
 

Author(s): Kaiming Wu, Jun Ma, Yanfeng Zhan, Kuanzhi Liu, Ziyin Ye, Jianhui Chen, Kaiwu Xu, Hongli Huang, Yulong He

Journal: Cell. Physiol. Biochem.. 2018 ;49(2):545-554.

 

Colon cancer, also known as colorectal cancer (CRC), is one of the most common malignant tumors globally. Although significant advances have been made for developing novel therapeutics, the mechanisms of progression of colorectal cancer are still poorly understood.

Last Updated: 31 Dec 1969

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SNHG6 Promotes Tumor Growth via Repression of P21 in Colorectal Cancer.
 

Author(s): Zhaoming Li, Ran Qiu, Xia Qiu, Tian Tian

Journal: Cell. Physiol. Biochem.. 2018 ;49(2):463-478.

 

SNHG6 (Small Nucleolar RNA Host Gene 6) is a novel non-coding RNA (ncRNA) and its cellular function is largely unknown.

Last Updated: 31 Dec 1969

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[Results of a multicentric colorectal cancer screening program in Chile].
 

Author(s): Francisco López-Kostner, Alejandro J Zárate, Alejandra Ponce, Udo Kronberg, Hiroshi Kawachi, Takuya Okada, Masahiro Tsubaki, Takashi Ito, Tetsuro Nishikage, Koji Tanaka, Tatsuyuki Kawano, Yoshinobu Eishi, Paulina Peñaloza, Ricardo Estela, Stanko Karelovic, Sergio Flores

Journal: Rev Med Chil. 2018 Jun;146(6):685-692.

 

Colorectal Cancer Screening Programs (CRCSP) are widely accepted in developed countries. Unfortunately, financial restrictions, low adherence rate and variability on colonoscopy standardization hamper the implementation of CRCSP in developing countries.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Colorectal Cancer" returned 1476 free, full-text review articles on human participants. First 3 results:

Cumulative evidence for relationships between multiple variants in 8q24 and colorectal cancer incidence.
 

Author(s): Yu Tong, Huiqing Wang, Shiping Li, Fengyan Zhao, Junjie Ying, Yi Qu, Dezhi Mu

Journal: Medicine (Baltimore). 2018 Aug;97(35):e11990.

 

Genome-wide association studies (GWAS) have identified multiple independent cancer susceptibility loci at chromosome 8q24.We conducted a comprehensive research synopsis and meta-analysis to evaluate associations between 6 variants in 8q24 and risk of colorectal cancer using data from ...

Last Updated: 31 Dec 1969

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Comparison of robot-assisted surgery, laparoscopic-assisted surgery, and open surgery for the treatment of colorectal cancer: A network meta-analysis.
 

Author(s): Shihou Sheng, Tiancheng Zhao, Xu Wang

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11817.

 

The aim of this study was to find the better treatment for colorectal cancer (CRC) by comparing robot-assisted colorectal surgery (RACS), laparoscopic-assisted colorectal surgery (LACS), and open surgery using network meta-analysis.

Last Updated: 31 Dec 1969

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Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature.
 

Author(s): Matthew Olumuyiwa Bojuwoye, Abdulfatai Bamidele Olokoba, Olumuyiwa Ayotunde Ogunlaja, Sulaiman Olayide Agodirin, Olatunde Kazeem Ibrahim, Kenechukwu Chukwuemeka Okonkwo, Aminu Mansa Aliyu

Journal:

 

Familial adenomatous polyposis syndrome is a rare condition characterized by the presence of numerous adenomatous polyps in the gastrointestinal tract and associated with risk for colorectal cancer. The disease is scarcely reported in Nigeria and this is the index report in Ilorin. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase 2 Study of Lamivudine in Patients With p53 Mutant Metastatic Colorectal Cancer
 

Status: Recruiting

Condition Summary: Colorectal Cancer Metastatic

 

Last Updated: 3 Apr 2018

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Circulating Tumor DNA Analysis to Optimize Treatment for Patients With Colorectal Cancer
 

Status: Recruiting

Condition Summary: Colorectal Cancer

 

Last Updated: 16 Aug 2018

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