Collagenous Colitis

Common Name(s)

Collagenous Colitis

Collagenous colitis is a type of inflammatory bowel disease that affects the colon. It is a form of microscopic colitis, which means that the inflammation is only visible when a biopsy is examined under a microscope; the inflammation cannot be seen or diagnosed from colonoscopy or sigmoidoscopy. Signs and symptoms may be ongoing or intermittent and may include chronic, watery, non-bloody diarrhea and abdominal pain or cramps. The exact underlying cause is unknown but may relate to a bacteria, a virus, an autoimmune response, and/or a genetic predisposition. Treatment for collagenous colitis varies depending on the symptoms and severity in each individual. In some cases, the condition resolves on its own.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Collagenous Colitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Collagenous Colitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Collagenous Colitis" returned 78 free, full-text research articles on human participants. First 3 results:

An in vitro model to evaluate the impact of the soluble factors from the colonic mucosa of collagenous colitis patients on T cells: enhanced production of IL-17A and IL-10 from peripheral CD4⁺ T cells.
 

Author(s): Ashok Kumar Kumawat, Nils Nyhlin, Anna Wickbom, Curt Tysk, Johan Bohr, Olof Hultgren, Elisabeth Hultgren Hörnquist

Journal: Mediators Inflamm.. 2014 ;2014():879843.

 

Soluble factors from intestinal mucosal cells contribute to immune homeostasis in the gut. We have established an in vitro model to investigate the regulatory role of soluble factors from inflamed intestinal mucosa of collagenous colitis (CC) patients in the differentiation of T cells. ...

Last Updated: 21 Oct 2014

Go To URL
Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis.
 

Author(s): Stephan Miehlke, Ahmed Madisch, Limas Kupcinskas, Dalius Petrauskas, Günter Böhm, Hans-Joachim Marks, Michael Neumeyer, Torben Nathan, Fernando Fernández-Bañares, Roland Greinwald, Ralf Mohrbacher, Michael Vieth, Ole K Bonderup,

Journal: Gastroenterology. 2014 May;146(5):1222-30.e1-2.

 

Studies reporting that budesonide is effective for the treatment of collagenous colitis have been small and differed in efficacy measures. Mesalamine has been proposed as a treatment option for collagenous colitis, although its efficacy has never been investigated in placebo-controlled ...

Last Updated: 18 Apr 2014

Go To URL
Collagenous colitis and ankylosing spondylitis.
 

Author(s): Laura López-Vives, Núria del Castillo, Paula Estrada, Xavier Juanola

Journal: Reumatol Clin. ;9(6):385.

 

Last Updated: 4 Nov 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Collagenous Colitis" returned 5 free, full-text review articles on human participants. First 3 results:

Collagenous colitis in children and adolescents: study of 7 cases and literature review.
 

Author(s): Xiuli Liu, Shu-Yuan Xiao, Thomas P Plesec, Wei Jiang, John R Goldblum, Audrey J Lazenby

Journal: Mod. Pathol.. 2013 Jun;26(6):881-7.

 

The aim of this study is to examine the clinical and pathologic characteristics of collagenous colitis (CC) in children and adolescents. Seven patients (five females and two males, median age: 13 years, ranging from 4 to 16) were included. Four (of 7, 57%) patients presented with ...

Last Updated: 3 Jun 2013

Go To URL
Long-term natural history and complications of collagenous colitis.
 

Author(s): Hugh J Freeman

Journal: Can. J. Gastroenterol.. 2012 Sep;26(9):627-30.

 

Microscopic forms of colitis have been described, including collagenous colitis, a possibly heterogeneous disorder. Collagenous colitis most often appears to have an entirely benign clinical course that usually responds to limited treatment. Sometimes significant extracolonic disorders, ...

Last Updated: 20 Sep 2012

Go To URL
[Collagenous gastritis and ileo-colitis occurred in autoimmune context: report of a case and review of the literature].
 

Author(s): Gilles Macaigne, Jean-François Boivin, Florence Harnois, Claude Chayette, Dorian Dikov, Sadek Cheaib, Marie-Luce Auriault

Journal: Gastroenterol. Clin. Biol.. 2010 Sep;34(8-9):e1-6.

 

Collagenous colitis belongs to the group of microscopic colitis. The aetiology and pathogenesis are unknown but different pathogenic hypothesis, autoimmune, infectious, alimentary and medicinal being are advanced, the last one being the most frequent aetiology. The collagenous gastritis ...

Last Updated: 29 Sep 2010

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Usefulness of Chromoendoscopy in Diagnosing Microscopic Colitis
 

Status: Recruiting

Condition Summary: Chronic Diarrhoea; Lymphocytic Colitis; Collagenous Colitis

 

Last Updated: 4 Jan 2012

Go to URL