Cold Contact Urticaria

Common Name(s)

Cold Contact Urticaria

Cold contact urticaria, often referred to as simply cold urticaria, is a chronic, reactive skin disorder. Major symptoms may include abnormal reddening of the skin, hives, swelling and itching after exposure of the skin to cold, cold water, and cold objects. Symptoms typically develop within two to five minutes after exposure to the triggering substance or situation and last for one to two hours. The cause of cold contact urticaria isn't clear. Some cases are secondary to underlying conditions (blood conditions or infectious diseases).  As much as possible, people with cold contact urticaria should avoid exposure to cold air as well as cold water. Treatment for cold contact urticaria may include antihistamines taken before cold exposure.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cold Contact Urticaria" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cold Contact Urticaria" returned 2 free, full-text research articles on human participants. First 3 results:

Up-dosing with bilastine results in improved effectiveness in cold contact urticaria.
 

Author(s): K Krause, A Spohr, T Zuberbier, M K Church, M Maurer

Journal: Allergy. 2013 Jul;68(7):921-8.

 

Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice is nonsedating antihistamines, dosages of which may be increased up to fourfold if ...

Last Updated: 15 Jul 2013

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Mast cell dependent vascular changes associated with an acute response to cold immersion in primary contact urticaria.
 

Author(s): Joseph Meyer, Alexander M Gorbach, Wei-Min Liu, Nevenka Medic, Michael Young, Celeste Nelson, Sarah Arceo, Avanti Desai, Dean D Metcalfe, Hirsh D Komarow

Journal: PLoS ONE. 2013 ;8(2):e56773.

 

While a number of the consequences of mast cell degranulation within tissues have been documented including tissue-specific changes such as bronchospasm and the subsequent cellular infiltrate, there is little known about the immediate effects of mast cell degranulation on the associated ...

Last Updated: 1 Mar 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cold Contact Urticaria" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cold Contact Urticaria Treatment With Rilonacept
 

Status: Recruiting

Condition Summary: Cold Contact Urticaria

 

Last Updated: 20 Jun 2014

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Cold Urticaria Treatment With Xolair
 

Status: Recruiting

Condition Summary: Cold Contact Urticaria

 

Last Updated: 11 Jun 2014

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