Coccidioidomycosis

Common Name(s)

Coccidioidomycosis

Coccidioidomycosis, also known as ‘Valley Fever,’ is a fungal infection caused by coccidioides. Coccidiodes is a pathogenic fungus commonly found in dry desert soil that can be stirred into the air by anything that disrupts the soil. Once in the air, the fungus may be inhaled into the lungs. Coccidioidomycosis can cause fever, chest pain, coughing, and other flu-like symptoms or pneumonia. Mild cases often resolve without treatment. In more severe cases, the infection can develop into chronic pneumonia and doctors will prescribe antifungal medications.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Coccidioidomycosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Coccidioidomycosis" returned 232 free, full-text research articles on human participants. First 3 results:

Coccidioidomycosis among Workers Constructing Solar Power Farms, California, USA, 2011-2014.
 

Author(s): Jason A Wilken, Gail Sondermeyer, Dennis Shusterman, Jennifer McNary, Duc J Vugia, Ann McDowell, Penny Borenstein, Debra Gilliss, Benedict Ancock, Janice Prudhomme, Deborah Gold, Gayle C Windham, Lauren Lee, Barbara L Materna

Journal: Emerging Infect. Dis.. 2015 Nov;21(11):1997-2005.

 

Coccidioidomycosis is associated with soil-disruptive work in Coccidioides-endemic areas of the southwestern United States. Among 3,572 workers constructing 2 solar power-generating facilities in San Luis Obispo County, California, USA, we identified 44 patients with symptom onset ...

Last Updated: 21 Oct 2015

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Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models.
 

Author(s): Lisa F Shubitz, Hien T Trinh, John N Galgiani, Maria L Lewis, Annette W Fothergill, Nathan P Wiederhold, Bridget M Barker, Eric R G Lewis, Adina L Doyle, William J Hoekstra, Robert J Schotzinger, Edward P Garvey

Journal: Antimicrob. Agents Chemother.. 2015 Dec;59(12):7249-54.

 

Coccidioidomycosis, or valley fever, is a growing health concern endemic to the southwestern United States. Safer, more effective, and more easily administered drugs are needed especially for severe, chronic, or unresponsive infections. The novel fungal CYP51 inhibitor VT-1161 demonstrated ...

Last Updated: 20 Nov 2015

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The Changing Epidemiology of Coccidioidomycosis in Los Angeles (LA) County, California, 1973-2011.
 

Author(s): Ramon E Guevara, Tasneem Motala, Dawn Terashita

Journal:

 

Coccidioidomycosis, also known as Valley Fever, is often thought of as an endemic disease of central California exclusive of Los Angeles County. The fungus that causes Valley Fever, Coccidioides spp., grows in previously undisturbed soil of semi-arid and arid environments of certain ...

Last Updated: 28 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Coccidioidomycosis" returned 32 free, full-text review articles on human participants. First 3 results:

Peritoneal Coccidioidomycosis: a Rare Case Report and Review of the Literature.
 

Author(s): Tina R Storage, Joshua Segal, Janice Brown

Journal: J Gastrointestin Liver Dis. 2015 Dec;24(4):527-30.

 

Coccidioidomycosis is a fungal infection endemic to the southwestern United States that typically causes a self-limited pulmonary illness. Extrapulmonary dissemination is extremely rare and typically localized to the skin, bone, and meninges. The gastrointestinal system has generally ...

Last Updated: 23 Dec 2015

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Coccidioidomycosis and the skin: a comprehensive review.
 

Author(s): Sandra Cecilia Garcia Garcia, Julio Cesar Salas Alanis, Minerva Gomez Flores, Sergio Eduardo Gonzalez Gonzalez, Lucio Vera Cabrera, Jorge Ocampo Candiani

Journal: An Bras Dermatol. ;90(5):610-9.

 

Coccidioidomycosis is a highly prevalent disease in the Western hemisphere. It is considered one of the most virulent primary fungal infections. Coccidioides species live in arid and semi-arid regions, causing mainly pulmonary infection through inhalation of arthroconidia although ...

Last Updated: 12 Nov 2015

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THE TREATMENT OF COCCIDIOIDOMYCOSIS.
 

Author(s): Neil M Ampel

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2015 Sep;57 Suppl 19():51-6.

 

Therapy of coccidioidomycosis continues to evolve. For primary pulmonary disease, antifungal therapy is frequently not required while prolonged courses of antifungals are generally needed for those in whom extrathoracic disseminated has occurred. Intravenous amphotericin B should ...

Last Updated: 15 Oct 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sertraline in Addition to Standard of Care Treatment for Coccidioidomycosis
 

Status: Not yet recruiting

Condition Summary: Coccidioidomycosis

 

Last Updated: 16 Sep 2016

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Early Fluconazole Treatment for Coccidiodomycosis Pneumonia
 

Status: Recruiting

Condition Summary: Coccidioidomycosis

 

Last Updated: 1 Sep 2016

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Pathogenesis and Genetics of Disseminated or Refractory Coccidioidomycosis
 

Status: Recruiting

Condition Summary: Coccidioidomycosis

 

Last Updated: 31 Aug 2016

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