Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1467 free, full-text research articles on human participants. First 3 results:

Clostridium difficile Infection.
 

Author(s): Daniel A Leffler, J Thomas Lamont

Journal: N. Engl. J. Med.. 2015 Jul;373(3):287-8.

 

Last Updated: 16 Jul 2015

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Burden of Clostridium difficile infection in the United States.
 

Author(s): Fernanda C Lessa, Lisa G Winston, L Clifford McDonald,

Journal: N. Engl. J. Med.. 2015 Jun;372(24):2369-70.

 

Last Updated: 11 Jun 2015

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Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012.
 

Author(s): D W Eyre, L Tracey, B Elliott, C Slimings, P G Huntington, R L Stuart, T M Korman, G Kotsiou, R McCann, D Griffiths, W N Fawley, P Armstrong, K E Dingle, A S Walker, T E Peto, D W Crook, M H Wilcox, T V Riley

Journal:

 

We describe an Australia-wide Clostridium difficile outbreak in 2011 and 2012 involving the previously uncommon ribotype 244. In Western Australia, 14 of 25 cases were community-associated, 11 were detected in patients younger than 65 years, 14 presented to emergency/outpatient ...

Last Updated: 19 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 178 free, full-text review articles on human participants. First 3 results:

[Clostridium difficile spores and its relevance in the persistence and transmission of the infection].
 

Author(s): Jonathan Barra-Carrasco, Cristian Hernández-Rocha, Patricio Ibáñez, Ana M Guzmán-Durán, Manuel Álvarez-Lobos, Daniel Paredes-Sabja

Journal: Rev Chilena Infectol. 2014 Dec;31(6):694-703.

 

C. difficile is an anaerobic spore former pathogen and the most important etiologic agent of nosocomial and community acquired antibiotics associated diarrheas. C. difficile infections (CDI) are responsible for an elevated rate of morbidity in developed and developing countries. Although ...

Last Updated: 14 Feb 2015

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Enterococci, Clostridium difficile and ESBL-producing bacteria: epidemiology, clinical impact and prevention in ICU patients.
 

Author(s): Jan A Sidler, Manuel Battegay, Sarah Tschudin-Sutter, Andreas F Widmer, Maja Weisser

Journal:

 

Most hospital-acquired infections arise from colonising bacteria. Intensive care patients and immunocompromised individuals are at highest risk for microbial invasion and subsequent infection due to multiple invasive procedures in addition to frequent application of chemotherapeutics ...

Last Updated: 25 Sep 2014

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Molecular epidemiology of Clostridium difficile for clinical practice.
 

Author(s): Sarah Tschudin-Sutter

Journal:

 

During the last decade, the world has witnessed numerous outbreaks of Clostridium difficile infections (CDI) in healthcare settings. Increasing incidence rates of CDI have been mainly attributed to the successful global spread of a more virulent strain of C. difficile - namely PCR-ribotype ...

Last Updated: 11 Sep 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of CB-183,315 in Patients With Clostridium Difficile Associated Diarrhea
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 21 Jul 2015

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Study of a Candidate Clostridium Difficile Toxoid Vaccine in Subjects at Risk for C. Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 14 May 2015

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The Risk for Clostridium Difficile Colitis During Hospitalization in Asymptomatic Carriers
 

Status: Not yet recruiting

Condition Summary: Clostridium Difficile; Colitis

 

Last Updated: 13 Feb 2014

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