Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1628 free, full-text research articles on human participants. First 3 results:

Notice to Readers: The Effect of Falsified Clostridium difficile Infections Surveillance Data on Results Reported in MMWR.
 

Author(s):

Journal:

 

In 2012, MMWR published the report, "Vital Signs: Preventing Clostridium difficile Infections," which examined Clostridium difficile infection (CDI) surveillance data. This report contained several errors pertaining to Emerging Infections Program (EIP) data. These errors occurred ...

Last Updated: 11 Sep 2015

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Medical Devices; Immunology and Microbiology Devices; Classification of Clostridium Difficile Toxin Gene Amplification Assay. Final order.
 

Author(s):

Journal: Fed Regist. 2015 Aug;80(166):51938-9.

 

The Food and Drug Administration (FDA) is classifying Clostridium difficile (C. difficile) toxin gene amplification assay into class II (special controls). The Agency is classifying the device into class II (special controls) in order to provide a reasonable assurance of safety and ...

Last Updated: 27 Aug 2015

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Recommendations for the management of symptomatic Clostridium difficile infection (CDI).
 

Author(s): Anna Piekarska,

Journal: Przegl Epidemiol. 2015 ;69(2):289-90, 401-2.

 

Last Updated: 3 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 201 free, full-text review articles on human participants. First 3 results:

Fecal Microbiota Transplantation for Clostridium difficile-Associated Diarrhea.
 

Author(s): Nathaniel A Cohen, Ronen Ben Ami, Hanan Guzner-Gur, Moshe E Santo, Zamir Halpern, Nitsan Maharshak

Journal: Isr. Med. Assoc. J.. 2015 Aug;17(8):510-4.

 

Clostridium difficile-associated diarrhea is a problem most hospital-based physicians will face in their career. This review aims to refresh current knowledge with regard to Clostridium difficile infection and bring physicians up to date with the latest developments in the growing ...

Last Updated: 23 Sep 2015

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Clostridium difficile infection seasonality: patterns across hemispheres and continents - a systematic review.
 

Author(s): Luis Furuya-Kanamori, Samantha J McKenzie, Laith Yakob, Justin Clark, David L Paterson, Thomas V Riley, Archie C Clements

Journal:

 

Studies have demonstrated seasonal variability in rates of Clostridium difficile infection (CDI). Synthesising all available information on seasonality is a necessary step in identifying large-scale epidemiological patterns and elucidating underlying causes.

Last Updated: 17 Mar 2015

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Clostridium difficile drug pipeline: challenges in discovery and development of new agents.
 

Author(s): Angie M Jarrad, Tomislav Karoli, Mark A T Blaskovich, Dena Lyras, Matthew A Cooper

Journal: J. Med. Chem.. 2015 Jul;58(13):5164-85.

 

In the past decade Clostridium difficile has become a bacterial pathogen of global significance. Epidemic strains have spread throughout hospitals, while community acquired infections and other sources ensure a constant inoculation of spores into hospitals. In response to the increasing ...

Last Updated: 9 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of a Candidate Clostridium Difficile Toxoid Vaccine (Cdiffense) in Subjects at Risk for C. Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 11 Dec 2015

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The Risk for Clostridium Difficile Colitis During Hospitalization in Asymptomatic Carriers
 

Status: Not yet recruiting

Condition Summary: Clostridium Difficile; Colitis

 

Last Updated: 13 Feb 2014

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Vancomycin Prophylaxis in Recurrent Clostridium Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 10 Sep 2014

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