Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1909 free, full-text research articles on human participants. First 3 results:

Hospital readmission with Clostridium difficile infection as a secondary diagnosis is associated with worsened outcomes and greater revenue loss relative to principal diagnosis: A retrospective cohort study.
 

Author(s): Marya D Zilberberg, Brian H Nathanson, Stephen Marcella, John Jay Hawkshead, Andrew F Shorr

Journal: Medicine (Baltimore). 2018 Sep;97(36):e12212.

 

Recurrent Clostridium difficile infection (rCDI) requiring rehospitalization contributes to poor outcomes, which may differ between patients hospitalized with versus for it.We performed a multicenter retrospective cohort study of rehospitalized adults surviving initial CDI hospitalization. ...

Last Updated: 31 Dec 1969

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Case series of successful treatment with fecal microbiota transplant (FMT) oral capsules mixed from multiple donors even in patients previously treated with FMT enemas for recurrent Clostridium difficile infection.
 

Author(s): Mahtab Chehri, Alice Højer Christensen, Sofie Ingdam Halkjær, Stig Günther, Andreas Munk Petersen, Morten Helms

Journal: Medicine (Baltimore). 2018 Aug;97(31):e11706.

 

Studies have shown that fecal microbiota transplantation (FMT) is a safe and highly efficient treatment for recurrent Clostridium difficile infection (rCDI). However, it is still unknown if one versus multiple donors or enemas versus capsule FMT are most efficient.

Last Updated: 31 Dec 1969

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Molecular epidemiology and antimicrobial susceptibility of human Clostridium difficile isolates from a single institution in Northern China.
 

Author(s): Baoya Wang, Zhi Lv, Pingping Zhang, Jianrong Su

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11219.

 

Because the epidemiology of Clostridium difficile infection (CDI) is region-specific, the present study was undertaken to examine the epidemiology of C difficile outbreaks in Beijing, China.Eighty nonduplicate isolates were collected from March, 2016 to December, 2016. The molecular ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 258 free, full-text review articles on human participants. First 3 results:

Infections: A Global Overview of Drug Sensitivity and Resistance Mechanisms.
 

Author(s): Saeed S Banawas

Journal:

 

is the most prevalent causative pathogen of healthcare-associated diarrhea. Notably, over the past 10 years, the number of outbreaks has increased with the rate of morbidity and mortality. The occurrence and spread of strains that are resistant to multiple antimicrobial drugs complicate ...

Last Updated: 31 Dec 1969

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Faecal Microbiota Transplantation for Clostridium Difficile - a local perspective.
 

Author(s): C Diamond, T McNeilly

Journal: Ulster Med J. 2017 May;86(2):108-110.

 

Clostridium Difficile represents one of the major challenges of the antimicrobial era with associated significant morbidity. Treatment options are limited to a number of specific antibiotics with significant failure rates. Faecal Microbiota Transplantation has been recognised as a ...

Last Updated: 31 Dec 1969

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Advances in the diagnosis and treatment of Clostridium difficile infections.
 

Author(s): Zhong Peng, Lifen Ling, Charles W Stratton, Chunhui Li, Christopher R Polage, Bin Wu, Yi-Wei Tang

Journal:

 

Clostridium difficile is a leading cause of antibiotic-associated diarrhea worldwide. The diagnosis of C. difficile infection (CDI) requires both clinical manifestations and a positive laboratory test for C. difficile and/or its toxins. While antibiotic therapy is the treatment of ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain
 

Status: Not yet recruiting

Condition Summary: Clostridium Difficile

 

Last Updated: 8 Dec 2017

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Last Updated: 7 Aug 2018

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Last Updated: 22 Feb 2017

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