Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1708 free, full-text research articles on human participants. First 3 results:

Clinical features and characteristics of Clostridium difficile PCR-ribotype 176 infection: results from a 1-year university hospital internal ward study.
 

Author(s): Jiri Drabek, Otakar Nyc, Marcela Krutova, Jan Stovicek, Jana Matejkova, Radan Keil

Journal:

 

Clostridium difficile infection (CDI) is a major cause of antibiotic-associated diarrhoea. Given an increasing CDI incidence and global spread of epidemic ribotypes, a 1-year study was performed to analyse the molecular characteristics of C. difficile isolates and associated clinical ...

Last Updated: 24 Dec 2015

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A bedside test for Clostridium Difficile infection: an Emergency Department use. Preliminary results.
 

Author(s): D Marsiliani, G De Marco, C Petruzziello, G Merra, F Franceschi, V Ojetti

Journal: Eur Rev Med Pharmacol Sci. 2015 Sep;19(17):3169-72.

 

Clostridium Difficile (CD) infection is a severe cause of diarrhea in patients with prolonged hospitalization and/or previously treated with antibiotics. CD's A and B toxins are responsible for either diarrhea or septical status as well as other complications including toxic megacolon. ...

Last Updated: 24 Sep 2015

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Notice to Readers: The Effect of Falsified Clostridium difficile Infections Surveillance Data on Results Reported in MMWR.
 

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In 2012, MMWR published the report, "Vital Signs: Preventing Clostridium difficile Infections," which examined Clostridium difficile infection (CDI) surveillance data. This report contained several errors pertaining to Emerging Infections Program (EIP) data. These errors occurred ...

Last Updated: 11 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 213 free, full-text review articles on human participants. First 3 results:

From the hospital to the home--the rise and rise of Clostridium difficile infection.
 

Author(s): Lauren Tracey, Andrew Kirke, Paul Armstrong, Thomas V Riley

Journal: Aust Fam Physician. 2015 Oct;44(10):712-7.

 

Clostridium difficile infection (CDI) has emerged as a serious worldwide public health threat. Although C. difficile has always been a cause of diarrhoeal disease in patients presenting to general practice, the rates of community-associated CDI (CA CDI) have increased.

Last Updated: 21 Oct 2015

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Fecal Microbiota Transplantation for Clostridium difficile-Associated Diarrhea.
 

Author(s): Nathaniel A Cohen, Ronen Ben Ami, Hanan Guzner-Gur, Moshe E Santo, Zamir Halpern, Nitsan Maharshak

Journal: Isr. Med. Assoc. J.. 2015 Aug;17(8):510-4.

 

Clostridium difficile-associated diarrhea is a problem most hospital-based physicians will face in their career. This review aims to refresh current knowledge with regard to Clostridium difficile infection and bring physicians up to date with the latest developments in the growing ...

Last Updated: 23 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of a Candidate Clostridium Difficile Toxoid Vaccine (Cdiffense) in Subjects at Risk for C. Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 11 Dec 2015

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Vancomycin Prophylaxis in Recurrent Clostridium Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 10 Sep 2014

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Fecal Microbiota Transplantation in Recurrent or Refractory Clostridium Difficile Colitis
 

Status: Not yet recruiting

Condition Summary: Clostridium Difficile; Clostridium Difficile Infection

 

Last Updated: 10 Oct 2013

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