Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1861 free, full-text research articles on human participants. First 3 results:

Coinfection with 2 Clostridium difficile ribotypes in China: A case report.
 

Author(s): Liqian Wang, Yun Luo, Chen Huang, Shenghai Wu, Julian Ye, Xiaojun Song, Dazhi Jin, Xianjun Wang

Journal: Medicine (Baltimore). 2018 Mar;97(13):e9946.

 

Clostridium difficile infections (CDIs) have been reported in China, but detailed clinical symptoms of coinfection by 2 C difficile ribotypes have not been documented.

Last Updated: 31 Dec 1969

Go To URL
The zoonotic potential of Clostridium difficile from small companion animals and their owners.
 

Author(s): Denise Rabold, Werner Espelage, Muna Abu Sin, Tim Eckmanns, Alexander Schneeberg, Heinrich Neubauer, Nadine Möbius, Katja Hille, Lothar H Wieler, Christian Seyboldt, Antina Lübke-Becker

Journal:

 

Clostridium difficile infections (CDI) in humans range from asymptomatic carriage to life-threatening intestinal disease. Findings on C. difficile in various animal species and an overlap in ribotypes (RTs) suggest potential zoonotic transmission. However, the impact of animals for ...

Last Updated: 31 Dec 1969

Go To URL
In silico analysis of antibiotic-induced Clostridium difficile infection: Remediation techniques and biological adaptations.
 

Author(s): Eric W Jones, Jean M Carlson

Journal:

 

In this paper we study antibiotic-induced C. difficile infection (CDI), caused by the toxin-producing C. difficile (CD), and implement clinically-inspired simulated treatments in a computational framework that synthesizes a generalized Lotka-Volterra (gLV) model with SIR modeling ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 246 free, full-text review articles on human participants. First 3 results:

infection in the elderly: an update on management.
 

Author(s): Tomefa E Asempa, David P Nicolau

Journal:

 

The burden of infection (CDI) is profound and growing. CDI now represents a common cause of health care-associated diarrhea, and is associated with significant morbidity, mortality, and health care costs. CDI disproportionally affects the elderly, possibly explained by the following ...

Last Updated: 31 Dec 1969

Go To URL
Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis.
 

Author(s): Anca Trifan, Carol Stanciu, Irina Girleanu, Oana Cristina Stoica, Ana Maria Singeap, Roxana Maxim, Stefan Andrei Chiriac, Alin Ciobica, Lucian Boiculese

Journal: World J. Gastroenterol.. 2017 Sep;23(35):6500-6515.

 

To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated ...

Last Updated: 31 Dec 1969

Go To URL
Control of Infection by Defined Microbial Communities.
 

Author(s): James Collins, Jennifer M Auchtung

Journal: Microbiol Spectr. 2017 Sep;5(5):.

 

Each year in the United States, billions of dollars are spent combating almost half a million infections (CDIs) and trying to reduce the ∼29,000 patient deaths in which has an attributed role. In Europe, disease prevalence varies by country and level of surveillance, though yearly ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain
 

Status: Not yet recruiting

Condition Summary: Clostridium Difficile

 

Last Updated: 8 Dec 2017

Go to URL

Last Updated: 2 Aug 2016

Go to URL

Last Updated: 22 Feb 2017

Go to URL