Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1720 free, full-text research articles on human participants. First 3 results:

Recurrent bacteremia and liver abscess caused by Clostridium difficile: A case report.
 

Author(s): Hiroshi Morioka, Mitsutaka Iguchi, Teiji Kuzuya, Hiroshige Mikamo, Tetsuya Yagi

Journal: Medicine (Baltimore). 2017 Sep;96(35):e7969.

 

Clostridium difficile bacteremia (CDB) and liver abscess is a quite rare presentation of C. difficile infection.

Last Updated: 31 Aug 2017

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Risk of surgical site infection, acute kidney injury, and Clostridium difficile infection following antibiotic prophylaxis with vancomycin plus a beta-lactam versus either drug alone: A national propensity-score-adjusted retrospective cohort study.
 

Author(s): Westyn Branch-Elliman, John E Ripollone, William J O'Brien, Kamal M F Itani, Marin L Schweizer, Eli Perencevich, Judith Strymish, Kalpana Gupta

Journal:

 

The optimal regimen for perioperative antimicrobial prophylaxis is controversial. Use of combination prophylaxis with a beta-lactam plus vancomycin is increasing; however, the relative risks and benefits associated with this strategy are unknown. Thus, we sought to compare postoperative ...

Last Updated: 10 Jul 2017

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Antibiotic prophylaxis for surgical site infections as a risk factor for infection with Clostridium difficile.
 

Author(s): Aubrey Balch, Aaron M Wendelboe, Sara K Vesely, Dale W Bratzler

Journal:

 

We aimed to measure the association between 2013 guideline concordant prophylactic antibiotic use prior to surgery and infection with Clostridium difficile.

Last Updated: 16 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 215 free, full-text review articles on human participants. First 3 results:

The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact.
 

Author(s): Nienke Z Borren, Shadi Ghadermarzi, Susan Hutfless, Ashwin N Ananthakrishnan

Journal:

 

Clostridium difficile infection (CDI) is the most common healthcare associated infection and is highly prevalent in Europe and North America. Limited data is available on the prevalence of CDI in Asia. However, secular increases in prevalence of risk factors for CDI suggest that it ...

Last Updated: 2 May 2017

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Fecal microbiota transplantation - methods of treatment of recurrent Clostridium difficile infections and other diseases.
 

Author(s): Klaudia Juszczuk, Katarzyna Grudlewska, Agnieszka Mikucka, Eugenia Gospodarek

Journal:

 

Clostridium difficile is a serious epidemiological problem and particularly dangerous microorganism causing hospital infections. Currently, the treatment of C. difficile infections is the use of metronidazole or vancomycin. However, in some patients, recurrent infection difficult ...

Last Updated: 27 Mar 2017

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Infection prevention and control of Clostridium difficile: a global review of guidelines, strategies, and recommendations.
 

Author(s): Evelyn Balsells, Teodora Filipescu, Moe H Kyaw, Camilla Wiuff, Harry Campbell, Harish Nair

Journal: J Glob Health. 2016 Dec;6(2):020410.

 

Clostridium difficile is the leading cause of health care-associated infections. Given the high incidence of C. difficile infection (CDI) and the lack of primary prevention through immunization, health care professionals should be aware of the most current guidance, as well as strengths ...

Last Updated: 28 Dec 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 22 Feb 2017

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IMT for Primary Clostridium Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 4 Feb 2015

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Last Updated: 2 Aug 2016

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