Clostridium Difficile

Common Name(s)

Clostridium Difficile

Clostridium difficile colitis, also known as c. diff, is a type of bacterial infection that may affect the colon. The colon is the last portion of the gastrointestinal tract, which helps digest food and form stool. Clostridium difficile colitis can cause bloating, severe diarrhea, and abdominal pain. It is commonly related to overuse of antibiotics in older or hospitalized people. Physicians can diagnose clostridium difficile colitis by testing the stool for the bacteria or the toxins that it creates. Clostridium difficile colitis is treated with specific antibiotics to kill the bacteria, and other antibiotics are often stopped. Other newer treatments include probiotics and fecal transplants.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clostridium Difficile" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clostridium Difficile" returned 1859 free, full-text research articles on human participants. First 3 results:

Heat shock increases conjugation efficiency in Clostridium difficile.
 

Author(s): Joseph A Kirk, Robert P Fagan

Journal: Anaerobe. 2016 Dec;42():1-5.

 

Clostridium difficile infection has increased in incidence and severity over the past decade, and poses a unique threat to human health. However, genetic manipulation of C. difficile remains in its infancy and the bacterium remains relatively poorly characterised. Low-efficiency conjugation ...

Last Updated: 24 Sep 2016

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Henoch Schonlein purpura and Clostridium difficile infection: a hematologist's point of view.
 

Author(s): Delia Dima, Ciprian Tomuleasa, Mihnea Zdrenghea

Journal: J Gastrointestin Liver Dis. 2016 Sep;25(3):411.

 

Last Updated: 30 Sep 2016

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Analysis of risk factors and clinical manifestations associated with Clostridium difficile disease in Serbian hospitalized patients.
 

Author(s): Stojanović Predrag

Journal: Braz. J. Microbiol.. ;47(4):902-910.

 

Clostridium difficile is the leading cause of infectious diarrhoea in hospitalized patients. The aim of this study was to determine the risk factors important for the development of hospital-acquired Clostridium difficile-associated disease and clinical manifestations of Clostridium ...

Last Updated: 16 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clostridium Difficile" returned 236 free, full-text review articles on human participants. First 3 results:

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract.
 

Author(s): Jenessa A Winston, Casey M Theriot

Journal: Anaerobe. 2016 Oct;41():44-50.

 

Clostridium difficile is an anaerobic, Gram positive, spore-forming bacillus that is the leading cause of nosocomial gastroenteritis. Clostridium difficile infection (CDI) is associated with increasing morbidity and mortality, consequently posing an urgent threat to public health. ...

Last Updated: 22 May 2016

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Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections.
 

Author(s): Lynne Vernice McFarland, Metehan Ozen, Ener Cagri Dinleyici, Shan Goh

Journal: World J. Gastroenterol.. 2016 Mar;22(11):3078-104.

 

Antibiotic-associated diarrhea (AAD) and Clostridium difficile infections (CDI) have been well studied for adult cases, but not as well in the pediatric population. Whether the disease process or response to treatments differs between pediatric and adult patients is an important clinical ...

Last Updated: 23 Mar 2016

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Reactive Oxygen Species as Additional Determinants for Cytotoxicity of Clostridium difficile Toxins A and B.
 

Author(s): Claudia Frädrich, Lara-Antonia Beer, Ralf Gerhard

Journal:

 

Clostridium difficile infections can induce mild to severe diarrhoea and the often associated characteristic pseudomembranous colitis. Two protein toxins, the large glucosyltransferases TcdA and TcdB, are the main pathogenicity factors that can induce all clinical symptoms in animal ...

Last Updated: 22 Jan 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 5 Sep 2015

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IMT for Primary Clostridium Difficile Infection
 

Status: Recruiting

Condition Summary: Clostridium Difficile Infection

 

Last Updated: 4 Feb 2015

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Last Updated: 2 Aug 2016

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