Cloaca

Common Name(s)

Cloaca

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cloaca" for support, advocacy or research.

Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

Last Updated: 8 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cloaca" for support, advocacy or research.

Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

http://www.PullthruNetwork.org

Last Updated: 8 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cloaca" returned 10 free, full-text research articles on human participants. First 3 results:

Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations.
 

Author(s): R C-L Ng, D Matsumaru, A S-H Ho, M-M Garcia-Barceló, Z-W Yuan, D Smith, L Kodjabachian, P K-H Tam, G Yamada, V C-H Lui

Journal: Cell Death Differ.. 2014 Jun;21(6):978-89.

 

In mammalian urorectal development, the urorectal septum (urs) descends from the ventral body wall to the cloaca membrane (cm) to partition the cloaca into urogenital sinus and rectum. Defective urs growth results in human congenital anorectal malformations (ARMs), and their pathogenic ...

Last Updated: 6 May 2014

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Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations.
 

Author(s): S Miyagawa, M Harada, D Matsumaru, K Tanaka, C Inoue, C Nakahara, R Haraguchi, S Matsushita, K Suzuki, N Nakagata, R C-L Ng, K Akita, V C-H Lui, G Yamada

Journal: Cell Death Differ.. 2014 Jun;21(6):990-7.

 

The cloaca is temporally formed and eventually divided by the urorectal septum (URS) during urogenital and anorectal organ development. Although congenital malformations, such as anorectal malformations (ARMs), are frequently observed during this process, the underlying pathogenic ...

Last Updated: 6 May 2014

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Defining the molecular pathologies in cloaca malformation: similarities between mouse and human.
 

Author(s): Laura A Runck, Anna Method, Andrea Bischoff, Marc Levitt, Alberto Peña, Margaret H Collins, Anita Gupta, Shiva Shanmukhappa, James M Wells, Géraldine Guasch

Journal: Dis Model Mech. 2014 Apr;7(4):483-93.

 

Anorectal malformations are congenital anomalies that form a spectrum of disorders, from the most benign type with excellent functional prognosis, to very complex, such as cloaca malformation in females in which the rectum, vagina and urethra fail to develop separately and instead ...

Last Updated: 10 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cloaca" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response
 

Status: Recruiting

Condition Summary: Bloodstream Infections

 

Last Updated: 4 May 2015

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