Cleft Palate

Common Name(s)

Cleft Palate, Cleft palate, isolated

Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see {119530}). Dominantly inherited cleft soft palate in 4 generations has been reported ({6:Jenkins and Stady, 1980}); see {119570}.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cleft Palate" returned 675 free, full-text research articles on human participants. First 3 results:

3D analysis of effects of primary surgeries in cleft lip/palate children during the first two years of life.
 

Author(s): Karine Laskos Sakoda, Paula Karine Jorge, Cleide Felício Carvalho Carrara, Maria Aparecida de Andrade Moreira Machado, Fabrício Pinelli Valarelli, Arnaldo Pinzan, Thais Marchini Oliveira

Journal:

 

This study aimed at monitoring the maxillary growth of children with cleft lip/palate in the first two years of life, and to evaluate the effects of primary surgeries on dental arch dimensions. The sample consisted of the three-dimensional digital models of 25 subjects with unilateral ...

Last Updated: 7 Jun 2017

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A Comparative Study of Oral Microbiota in Infants with Complete Cleft Lip and Palate or Cleft Soft Palate.
 

Author(s): Agnieszka Machorowska-Pieniążek, Anna Mertas, Małgorzata Skucha-Nowak, Marta Tanasiewicz, Tadeusz Morawiec

Journal: Biomed Res Int. 2017 ;2017():1460243.

 

Few reports have been published on the early microbiota in infants with various types of cleft palate. We assessed the formation of the oral microbiota in infants with complete cleft lip and palate (CLP n = 30) or cleft soft palate (CSP n = 25) in the neonatal period (T1 time) and ...

Last Updated: 10 Apr 2017

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Polymorphic variants in VAX1 and the risk of nonsyndromic cleft lip with or without cleft palate in a population from northern China.
 

Author(s): Dongmei Li, Tingting Liu, Xiangbiao Meng, Qiang Guo, Jinna Shi, Yanru Hao, Xiaohui Jiao, Kewen Lv, Tao Song

Journal: Medicine (Baltimore). 2017 Apr;96(14):e6550.

 

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common craniofacial birth defects, and the etiology of NSCL/P involves both genetic and environmental factors. Genome-wide association study (GWAS) identified a novel susceptibility locus of ventral anterior ...

Last Updated: 6 Apr 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cleft Palate" returned 34 free, full-text review articles on human participants. First 3 results:

Feeding methods for children with cleft lip and/or palate: a systematic review.
 

Author(s): Giesse Albeche Duarte, Ramon Bossardi Ramos, Maria Cristina de Almeida Freitas Cardoso

Journal: Braz J Otorhinolaryngol. ;82(5):602-9.

 

Feeding difficulties in children with cleft lip and palate (CLP) are frequent and appear at birth due to impairment of sucking and swallowing functions. The use of appropriate feeding methods for the different types of cleft and the period of the child's life is of utmost importance ...

Last Updated: 27 Sep 2016

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20p12.3 deletion is rare cause of syndromic cleft palate: case report and review of literature.
 

Author(s): Saadia Amasdl, Abdelhafid Natiq, Aziza Sbiti, Maria Zerkaoui, Jaber Lyahyai, Saaid Amzazi, Thomas Liehr, Abdelaziz Sefiani

Journal:

 

Orofacial cleft (OFC) is one of the most common congenital malformations with a global incidence of approximately 1/700 live births. Clinically, OFCs can be syndromic or non-syndromic.

Last Updated: 4 Jan 2016

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A review of cleft lip and palate management: Experience of a Nigerian Teaching Hospital.
 

Author(s): Akinwale Adeyemi Efunkoya, Kelvin Uchenna Omeje, Ibiyinka Olushola Amole, Otasowie Daniel Osunde, Izegboya Olohitae Akpasa

Journal: Afr J Paediatr Surg. ;12(4):257-60.

 

Cleft lip (CL) and palate (CLP) management is multidisciplinary. A cleft team was formed in a Nigerian Tertiary Hospital to address the health needs of cleft patients in the centre.

Last Updated: 29 Dec 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 14 Dec 2016

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Improving Outcomes in Cleft Palate Surgery
 

Status: Recruiting

Condition Summary: Cleft Palate

 

Last Updated: 20 Oct 2015

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Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair
 

Status: Not yet recruiting

Condition Summary: Cleft Palate

 

Last Updated: 30 Jan 2017

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