Cleft Palate

Common Name(s)

Cleft Palate, Cleft palate, isolated

Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see {119530}). Dominantly inherited cleft soft palate in 4 generations has been reported ({6:Jenkins and Stady, 1980}); see {119570}.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cleft Palate" returned 677 free, full-text research articles on human participants. First 3 results:

[Transpalatal modified Le Fort I osteotomy for correction of maxillary hypoplasia in cleft lip and palate patients: a preliminary clinical application].
 

Author(s): Y Wu, Z L Li, X Wang, B Yi, L Ma

Journal: Beijing Da Xue Xue Bao. 2016 Jun;48(3):550-4.

 

To evaluate the surgical corrective results of maxillary hypoplasia in patients with cleft lip and palate withtranspalatal modified Le Fort I osteotomy.

Last Updated: 20 Jun 2016

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[Association study between candidate genes involved in cell-cell adhesion and non-syndromic cleft lip with or without cleft palate in Chinese population].
 

Author(s): Y Yuan, P Wang, Y H Wu-Chou, X Q Ye, S Z Huang, B Shi, K Wang, Z Q Wang, D J Liu, Z F Wang, T Wu, H Wang

Journal: Beijing Da Xue Xue Bao. 2016 Jun;48(3):403-8.

 

To explore the association and gene-environment interaction between single nucleotide polymorphisms (SNPs) involved in cell-cell adhesion and non-syndromic cleft lip with or without cleft palate (NSCL/P) among Chinese population.

Last Updated: 20 Jun 2016

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[Audiological and Otological Status of 45 Infants with Cleft Palate].
 

Author(s): Dian-yin Shi, Lian Zhou, Ying-ying Shang

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Apr;38(2):136-9.

 

To study the audiological and otological status of cleft palate infants with the application of distortion product otoacoustic emission (DPOAE), auditory brainstem response (ABR), tympanometry with 1000 Hz and 226 Hz probe tones.

Last Updated: 16 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cleft Palate" returned 35 free, full-text review articles on human participants. First 3 results:

20p12.3 deletion is rare cause of syndromic cleft palate: case report and review of literature.
 

Author(s): Saadia Amasdl, Abdelhafid Natiq, Aziza Sbiti, Maria Zerkaoui, Jaber Lyahyai, Saaid Amzazi, Thomas Liehr, Abdelaziz Sefiani

Journal:

 

Orofacial cleft (OFC) is one of the most common congenital malformations with a global incidence of approximately 1/700 live births. Clinically, OFCs can be syndromic or non-syndromic.

Last Updated: 4 Jan 2016

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Flap Necrosis after Palatoplasty in Patients with Cleft Palate.
 

Author(s): Percy Rossell-Perry

Journal: Biomed Res Int. 2015 ;2015():516375.

 

Palatal necrosis after palatoplasty in patients with cleft palate is a rare but significant problem encountered by any cleft surgeon. Few studies have addressed this disastrous complication and the prevalence of this problem remains unknown. Failure of a palatal flap may be attributed ...

Last Updated: 14 Aug 2015

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Current Controversies in Diagnosis and Management of Cleft Palate and Velopharyngeal Insufficiency.
 

Author(s): Pablo Antonio Ysunza, Gabriela M Repetto, Maria Carmen Pamplona, Juan F Calderon, Kenneth Shaheen, Konkgrit Chaiyasate, Matthew Rontal

Journal: Biomed Res Int. 2015 ;2015():196240.

 

One of the most controversial topics concerning cleft palate is the diagnosis and treatment of velopharyngeal insufficiency (VPI).

Last Updated: 14 Aug 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Timing of Primary Surgery for Cleft Palate
 

Status: Recruiting

Condition Summary: Cleft Palate

 

Last Updated: 26 May 2015

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Last Updated: 1 Sep 2016

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Improving Outcomes in Cleft Palate Surgery
 

Status: Recruiting

Condition Summary: Cleft Palate

 

Last Updated: 20 Oct 2015

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