Cleft Palate

Common Name(s)

Cleft Palate, Cleft palate, isolated

Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see {119530}). Dominantly inherited cleft soft palate in 4 generations has been reported ({6:Jenkins and Stady, 1980}); see {119570}.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cleft Palate" returned 491 free, full-text research articles on human participants. First 3 results:

A genome-wide study of de novo deletions identifies a candidate locus for non-syndromic isolated cleft lip/palate risk.
 

Author(s): Samuel G Younkin, Robert B Scharpf, Holger Schwender, Margaret M Parker, Alan F Scott, Mary L Marazita, Terri H Beaty, Ingo Ruczinski

Journal:

 

Copy number variants (CNVs) may play an important part in the development of common birth defects such as oral clefts, and individual patients with multiple birth defects (including clefts) have been shown to carry small and large chromosomal deletions. In this paper we investigate ...

Last Updated: 20 Feb 2014

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Last Updated: 29 Jan 2014

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Awareness, knowledge and attitude on cleft lip and palate among antenatal clinic attendees of tertiary hospitals in Nigeria.
 

Author(s): F J Owotade, O K Ogundipe, V I Ugboko, V N Okoje, H O Olasoji, O N Makinde, E O Orji

Journal: Niger J Clin Pract. ;17(1):6-9.

 

Adequate knowledge and awareness of cleft lip and palate (CLP) deformity may help to counter the negative beliefs and attitudes toward the condition. The objective of this study was to assess the level of awareness, knowledge and attitude of women attending antenatal clinics about CLP.

Last Updated: 11 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cleft Palate" returned 27 free, full-text review articles on human participants. First 3 results:

MOMENT--Management of Otitis Media with Effusion in Cleft Palate: protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey.
 

Author(s): Nicola L Harman, Iain A Bruce, Peter Callery, Stephanie Tierney, Mohammad Owaise Sharif, Kevin O'Brien, Paula R Williamson

Journal:

 

Cleft palate (CP) has an incidence of approximately 1 in 700. Children with CP are also susceptible to otitis media with effusion (OME), with approximately 90% experiencing nontrivial OME. There are several approaches to the management of OME in children with CP. The Management of ...

Last Updated: 22 Jul 2013

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[Prenatal diagnosis of cleft lip with or without cleft palate: retrospective study and review].
 

Author(s): A Guyot, V Soupre, M-P Vazquez, A Picard, J Rosenblatt, C Garel, M Gonzales, S Marlin, J-L Benifla, J-M Jouannic

Journal: J Gynecol Obstet Biol Reprod (Paris). 2013 Apr;42(2):151-8.

 

To evaluate the management of prenatally diagnosed cleft lip with or without cleft palate and the immediate postnatal outcome.

Last Updated: 26 Mar 2013

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The evolution of human genetic studies of cleft lip and cleft palate.
 

Author(s): Mary L Marazita

Journal: Annu Rev Genomics Hum Genet. 2012 ;13():263-83.

 

Orofacial clefts (OFCs)--primarily cleft lip and cleft palate--are among the most common birth defects in all populations worldwide, and have notable population, ethnicity, and gender differences in birth prevalence. Interest in these birth defects goes back centuries, as does formal ...

Last Updated: 13 Sep 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Timing of Primary Surgery for Cleft Palate
 

Status: Recruiting

Condition Summary: Cleft Palate

 

Last Updated: 15 Aug 2013

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An Investigation for the Optimal Timing of a Cleft Palate Repair
 

Status: Recruiting

Condition Summary: Cleft Palate

 

Last Updated: 23 Oct 2008

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Preoperative Antibiotics Study
 

Status: Recruiting

Condition Summary: Cleft Palates

 

Last Updated: 29 Jul 2013

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