Clear Cell Renal Cell Carcinoma

Common Name(s)

Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma is a cancer of the kidney.  The name "clear cell" refers to the appearance of the cancer cells when viewed with a microscope.   Clear cell renal cell carcinoma occurs when cells in the kidney quickly increase in number, creating a lump (mass).  Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.  Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy, chemotherapy, biological therapy, or targeted therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clear Cell Renal Cell Carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clear Cell Renal Cell Carcinoma" returned 508 free, full-text research articles on human participants. First 3 results:

Metastatic renal clear cell carcinoma to the rectum, lungs, ilium, and lymph nodes: A case report.
 

Author(s): Guoyang Zheng, Hanzhong Li, Ji Li, Xuebin Zhang, Yushi Zhang, Xingcheng Wu

Journal: Medicine (Baltimore). 2017 Jan;96(1):e5720.

 

Renal cell carcinoma metastasizing to rectum is very rare, and the unusual metastatic sites should be paid attention to during the follow-up of renal cell carcinoma.

Last Updated: 10 Jan 2017

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Low level of PDZ domain containing 1 (PDZK1) predicts poor clinical outcome in patients with clear cell renal cell carcinoma.
 

Author(s): Junfang Zheng, Lei Wang, Zhiqiang Peng, Ying Yang, Duiping Feng, Junqi He

Journal: EBioMedicine. 2017 Feb;15():62-72.

 

Clear cell renal cell carcinoma (ccRCC) is the most lethal neoplasm of the urologic system. Clinical therapeutic effect varies greatly between individual ccRCC patients, so there is an urgent need to develop prognostic molecular biomarkers to help clinicians identify patients in need ...

Last Updated: 20 Dec 2016

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Comparative proteomic profiling identifies potential prognostic factors for human clear cell renal cell carcinoma.
 

Author(s): Xiang Sun, Hongwei Zhang, Longhua Luo, Kezhao Zhong, Yushui Ma, Linlin Fan, Da Fu, Lijuan Wan

Journal: Oncol. Rep.. 2016 Dec;36(6):3131-3138.

 

The identification of markers for disease diagnostic, prognostic, or predictive purposes will have a great effect in improving patient management. Proteomic‑based approaches for biomarker discovery are promising strategies used in cancer research. In this study, we performed quantitative ...

Last Updated: 17 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clear Cell Renal Cell Carcinoma" returned 22 free, full-text review articles on human participants. First 3 results:

Coexistence of multiple myeloma and clear cell renal cell carcinoma: a case report and review of literature.
 

Author(s): Gaixiang Xu, Min Yang, Jian Huang, Jie Jin

Journal:

 

Coexistence of multiple myeloma (MM) and renal cell carcinoma (RCC) is an extremely rare condition. Nevertheless, there is a higher than expected incidence of co-occurrence of these two malignancies. Several case series, in the recent past, have postulated an association between MM ...

Last Updated: 11 Aug 2015

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Association of primary hyperparathyroidism and humoral hypercalcemia of malignancy in a patient with clear cell renal carcinoma.
 

Author(s): Letícia da Silva Gomes, Carolina A M Kulak, Tatiana Munhoz da Rocha Lemos Costa, Evandro Cezar Guerreiro Vasconcelos, Maurício de Carvalho, Victoria Zeghbi Cochenski Borba

Journal: Arch Endocrinol Metab. 2015 Feb;59(1):84-8.

 

Hypercalcemia is found frequently in patients with cancer. Besides the etiology related to the malignancy, other causes should be considered in the differential diagnostic, as primary hyperparathyroidism, granulomatous diseases and the use of thiazide diuretics. We present a case ...

Last Updated: 30 Apr 2015

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Frontiers in clinical and molecular diagnostics and staging of metastatic clear cell renal cell carcinoma.
 

Author(s): Anna M Czarnecka, Anna Kornakiewicz, Wojciech Kukwa, Cezary Szczylik

Journal: Future Oncol. 2014 May;10(6):1095-111.

 

The last few years have brought advances in the understanding of the molecular biology of metastatic clear cell renal cell carcinoma (RCC). Both preclinical research and clinical trials brought together results from the latest advancements in RCC diagnostic and staging. Understanding ...

Last Updated: 19 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 1 Dec 2016

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Nivolumab and Stereotactic Ablative Radiation Therapy (SAbR) for Metastatic Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Metastatic Clear Cell Renal Cell Carcinoma

 

Last Updated: 18 Nov 2016

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Addition of X4P-001 to Nivolumab Treatment in Patients With Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 8 Feb 2017

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