Clear Cell Renal Cell Carcinoma

Common Name(s)

Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma is a cancer of the kidney.  The name "clear cell" refers to the appearance of the cancer cells when viewed with a microscope.   Clear cell renal cell carcinoma occurs when cells in the kidney quickly increase in number, creating a lump (mass).  Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.  Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy, chemotherapy, biological therapy, or targeted therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clear Cell Renal Cell Carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clear Cell Renal Cell Carcinoma" returned 670 free, full-text research articles on human participants. First 3 results:

Rare ectopic metastasis from clear cell renal cell carcinoma to the chest wall after 10 years: A case report.
 

Author(s): Chunyang Jiang, Shan Zhao, Bingjun Yang, Tao Tang, Ruipeng Hou, Xiaoqin Liu, Hui Zhao

Journal: Medicine (Baltimore). 2018 May;97(19):e0687.

 

Clear cell renal cell carcinoma (CCRCC) is an aggressive tumor associated with a high risk of metastasis and very low survival rate. In addition, it can cause extensive blood metastasis to the lungs, bones, and other organs. Chest wall metastatic tumors from primary CCRCC are rare.

Last Updated: 31 Dec 1969

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Metabolomic study of human tissue and urine in clear cell renal carcinoma by LC-HRMS and PLS-DA.
 

Author(s): Joanna Nizioł, Vincent Bonifay, Krzysztof Ossoliński, Tadeusz Ossoliński, Anna Ossolińska, Jan Sunner, Iwona Beech, Adrian Arendowski, Tomasz Ruman

Journal: Anal Bioanal Chem. 2018 Jun;410(16):3859-3869.

 

Renal cell carcinoma (RCC) is the most prevalent and lethal malignancy of the kidney. Despite all the efforts made, no tissue biomarker is currently used in the clinical management of patients with kidney cancer. A search for possible biomarkers in urine for clear cell renal cell ...

Last Updated: 31 Dec 1969

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The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma.
 

Author(s): Damien Ambrosetti, Maeva Dufies, Bérengère Dadone, Matthieu Durand, Delphine Borchiellini, Jean Amiel, Jacques Pouyssegur, Nathalie Rioux-Leclercq, Gilles Pages, Fanny Burel-Vandenbos, Nathalie M Mazure

Journal:

 

Clear-cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer. Although ccRCC is characterized by common recurrent genetic abnormalities, including inactivation of the von Hippel-Lindau (vhl) tumor suppressor gene resulting in stabilization of hypoxia-inducible ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clear Cell Renal Cell Carcinoma" returned 29 free, full-text review articles on human participants. First 3 results:

Multiple metastases of clear-cell renal cell carcinoma to different region of the nasal cavity and paranasal sinus 3 times successively: A case report and literature review.
 

Author(s): Na Zhang, Bing Zhou, Qian Huang, Xiaohong Chen, Shunjiu Cui, Zhenxiao Huang, Yan Sun

Journal: Medicine (Baltimore). 2018 Apr;97(14):e0286.

 

Distant metastasis of clear-cell renal cell carcinoma (ccRCC) to the nasal cavity and paranasal sinus is rare. Endoscopic biopsy used to be performed for diagnosis when it is difficult for complete resection due to intense bleeding during surgery. According to previous literature, ...

Last Updated: 31 Dec 1969

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Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma.
 

Author(s): Ali Mehdi, Yasser Riazalhosseini

Journal:

 

Clear cell renal cell carcinoma (ccRCC), the most common form of Kidney cancer, is characterized by frequent mutations of the von Hippel-Lindau () tumor suppressor gene in ~85% of sporadic cases. Loss of pVHL function affects multiple cellular processes, among which the activation ...

Last Updated: 31 Dec 1969

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[Diagnosis and treatment of isolated pancreatic metastases from renal clear cell carcinoma: Report of a case and review of literature].
 

Author(s): Ricardo Lucas García-Mayor Fernández, María Fernández-González

Journal: Cir Cir. ;85(5):436-439.

 

The development of pancreatic metastases in renal carcinoma is very uncommon. The aim of the paper is to present a clinical case of this disease and review the clinical presentation, diagnosis, and treatment.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnostic Imaging for Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 26 Sep 2017

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Study of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 6 Jul 2017

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Nivolumab and Stereotactic Ablative Radiation Therapy (SAbR) for Metastatic Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Metastatic Clear Cell Renal Cell Carcinoma

 

Last Updated: 20 Feb 2018

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