Clear Cell Renal Cell Carcinoma

Common Name(s)

Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma is a cancer of the kidney.  The name "clear cell" refers to the appearance of the cancer cells when viewed with a microscope.   Clear cell renal cell carcinoma occurs when cells in the kidney quickly increase in number, creating a lump (mass).  Though the exact cause of clear cell renal cell carcinoma is unknown, smoking, the excessive use of certain medications, and several genetic predisposition conditions (such as von Hippel Lindau syndrome) may contribute to the development of this type of cancer.  Treatment often begins with surgery to remove as much of the cancer as possible, and may be followed by radiation therapy, chemotherapy, biological therapy, or targeted therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Clear Cell Renal Cell Carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Clear Cell Renal Cell Carcinoma" returned 514 free, full-text research articles on human participants. First 3 results:

Identification of prognostic genes in kidney renal clear cell carcinoma by RNA‑seq data analysis.
 

Author(s): Yanqin Gu, Linfeng Lu, Lingfeng Wu, Hao Chen, Wei Zhu, Yi He

Journal: Mol Med Rep. 2017 Apr;15(4):1661-1667.

 

The present study aimed to analyze RNA-seq data of kidney renal clear cell carcinoma (KIRC) to identify prognostic genes. RNA‑seq data were downloaded from The Cancer Genome Atlas. Feature genes with a coefficient of variation (CV) >0.5 were selected using the genefilter package ...

Last Updated: 5 Mar 2017

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Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis.
 

Author(s): Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li

Journal: Mol Med Rep. 2017 Mar;15(3):1103-1108.

 

Tumor cells resistant to anoikis are considered to be candidates for metastasis. In the present study, the role of Tim‑3 in anoikis and its influence on the invasion of clear cell renal cell carcinoma (ccRCC) was investigated. Here, polyhydroxylethylmethacrylate (poly‑HEMA) was ...

Last Updated: 23 Jan 2017

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Metastatic renal clear cell carcinoma to the rectum, lungs, ilium, and lymph nodes: A case report.
 

Author(s): Guoyang Zheng, Hanzhong Li, Ji Li, Xuebin Zhang, Yushi Zhang, Xingcheng Wu

Journal: Medicine (Baltimore). 2017 Jan;96(1):e5720.

 

Renal cell carcinoma metastasizing to rectum is very rare, and the unusual metastatic sites should be paid attention to during the follow-up of renal cell carcinoma.

Last Updated: 10 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Clear Cell Renal Cell Carcinoma" returned 24 free, full-text review articles on human participants. First 3 results:

Clear cell papillary renal cell carcinoma, renal angiomyoadenomatous tumor, and renal cell carcinoma with leiomyomatous stroma relationship of 3 types of renal tumors: a review.
 

Author(s): Ondrej Hes, Eva Maria Compérat, Nathalie Rioux-Leclercq

Journal: Ann Diagn Pathol. 2016 Apr;21():59-64.

 

Renal angiomyoadenomatous tumor has been described in 2000, followed by description of clear cell papillary renal cell carcinoma in 2006. Discussions about possible relationship of both tumors were published since their description. The main differential diagnostic feature was considered ...

Last Updated: 4 Apr 2016

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Coexistence of multiple myeloma and clear cell renal cell carcinoma: a case report and review of literature.
 

Author(s): Gaixiang Xu, Min Yang, Jian Huang, Jie Jin

Journal:

 

Coexistence of multiple myeloma (MM) and renal cell carcinoma (RCC) is an extremely rare condition. Nevertheless, there is a higher than expected incidence of co-occurrence of these two malignancies. Several case series, in the recent past, have postulated an association between MM ...

Last Updated: 11 Aug 2015

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Association of primary hyperparathyroidism and humoral hypercalcemia of malignancy in a patient with clear cell renal carcinoma.
 

Author(s): Letícia da Silva Gomes, Carolina A M Kulak, Tatiana Munhoz da Rocha Lemos Costa, Evandro Cezar Guerreiro Vasconcelos, Maurício de Carvalho, Victoria Zeghbi Cochenski Borba

Journal: Arch Endocrinol Metab. 2015 Feb;59(1):84-8.

 

Hypercalcemia is found frequently in patients with cancer. Besides the etiology related to the malignancy, other causes should be considered in the differential diagnostic, as primary hyperparathyroidism, granulomatous diseases and the use of thiazide diuretics. We present a case ...

Last Updated: 30 Apr 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 2 May 2017

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Nivolumab and Stereotactic Ablative Radiation Therapy (SAbR) for Metastatic Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Metastatic Clear Cell Renal Cell Carcinoma

 

Last Updated: 18 Nov 2016

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Addition of X4P-001 to Nivolumab Treatment in Patients With Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Clear Cell Renal Cell Carcinoma

 

Last Updated: 8 Feb 2017

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