Churg-Strauss Syndrome

Common Name(s)

Churg-Strauss Syndrome, Allergic granulomatosis

Churg Strauss syndrome is a rare autoimmune condition characterized by asthma, high levels of eosinophils (a type of white blood cell that helps fight infection) in the blood and tissues, and inflammation of small to medium sized blood vessels (vasculitis). The inflamed vessels can affect various organ systems including the lungs, gastrointestinal tract, skin, heart and nervous system. The cause of Churg Strauss syndrome is unknown. While there is no cure, the condition can be successfully managed with early diagnosis and treatment.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Churg-Strauss Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Churg-Strauss Syndrome" returned 208 free, full-text research articles on human participants. First 3 results:

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) presenting as diffuse myositis.
 

Author(s): Marc-Etienne Parent, Sandrine Larue, Benjamin Ellezam

Journal:

 

Eosinophilic granulomatosis with polyangiitis is a complex multisystemic syndrome with heterogeneous presentation. Most often, there is a clinical history of asthma or other atopic conditions, and current presentation generally includes signs of cutaneous or pulmonary involvement. ...

Last Updated: 27 Nov 2014

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Spinal cord involvement of Churg-Strauss syndrome with multi-organ disorders.
 

Author(s): Chenlong Yang, Liang Wu, Tao Yang, Xiaofeng Deng, Yulun Xu

Journal: Neurol India. ;62(3):314-5.

 

Last Updated: 18 Jul 2014

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Acute coronary syndrome caused by coronary vasospasms associated with Churg-Strauss syndrome: effects of betamethasone therapy.
 

Author(s): Yuji Suzuki, Osamu Nishiyama, Toshiaki Sakai, Masanobu Niiyama, Tomonori Itoh, Motoyuki Nakamura

Journal: Intern. Med.. 2014 ;53(7):717-20.

 

A 42-year-old woman with a history of aspirin-induced asthma was admitted with severe chest pain. Emergency coronary angiography revealed coronary artery spasms. The administration of vasodilators did not suppress the anginal symptoms, and the differential white blood cell count continued ...

Last Updated: 3 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Churg-Strauss Syndrome" returned 14 free, full-text review articles on human participants. First 3 results:

Multiple cerebral and cerebellar infarcts as the first clinical manifestation in a patient with Churg-Strauss syndrome: case report and literature review.
 

Author(s): Meng-Ju Cheng, Pai-Hao Huang, Pin-Wen Liao, Jen-Tse Chen, Tsuey-Ru Chiang

Journal: Acta Neurol Taiwan. 2012 Dec;21(4):169-75.

 

Churg-Strauss syndrome (CSS) is a rare autoimmune disease with small-vessel vasculitis. Neurological manifestation of CSS is common. Central nervous system is less frequently involved than that of peripheral nervous system.

Last Updated: 18 Jan 2013

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Churg-Strauss syndrome presenting with acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis.
 

Author(s): Daigoro Hirohama, Junichi Hoshino, Keiichi Sumida, Eiko Hasegawa, Rikako Hiramatsu, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Naoki Sawa, Fumi Takemoto, Yoshifumi Ubara, Shigeko Hara, Kenichi Ohashi, Kenmei Takaichi

Journal: Intern. Med.. 2012 ;51(12):1555-60.

 

We encountered an unusual and rare case of 59-year-old woman with Churg-Strauss syndrome (CSS) showing myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-related acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis. To date, reports in English ...

Last Updated: 25 Jun 2012

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Churg-Strauss syndrome complicated by chronic periaortitis: a case report and review of the literature.
 

Author(s): Kenji Fujii, Yuji Hidaka

Journal: Intern. Med.. 2012 ;51(1):109-12.

 

We present a case of Churg-Strauss syndrome complicated by chronic periaortitis. A 68-year-old man presented with wheezing, dyspnea, purpurae, and numbness of the extremities. Antineutrophil cytoplasmic antibodies were absent; however, eosinophilia, a pulmonary infiltrative shadow ...

Last Updated: 4 Jan 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Investigate Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis
 

Status: Recruiting

Condition Summary: Churg-Strauss Syndrome

 

Last Updated: 23 Jul 2015

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Determining Disease Activity Biomarkers in Individuals With Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)
 

Status: Recruiting

Condition Summary: Eosinophilic Granulomatosis With Polyangiitis; Churg-Strauss Syndrome

 

Last Updated: 13 Feb 2015

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The ANCA Vasculitis Questionnaire (AAV-PRO©)
 

Status: Recruiting

Condition Summary: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA); Churg-Strauss Syndrome (CSS); Granulomatosis With Polyangiitis (Wegener's) (GPA); Wegener Granulomatosis (WG); Microscopic Polyangiitis (MPA); ANCA-Associated Vasculitis (AAV); Vasculitis

 

Last Updated: 28 Jul 2015

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