Churg-Strauss Syndrome

Common Name(s)

Churg-Strauss Syndrome

Churg Strauss syndrome is a rare autoimmune condition characterized by asthma, high levels of eosinophils (a type of white blood cell that helps fight infection) in the blood and tissues, and inflammation of small to medium sized blood vessels (vasculitis). The inflamed vessels can affect various organ systems including the lungs, gastrointestinal tract, skin, heart and nervous system. The cause of Churg Strauss syndrome is unknown. While there is no cure, the condition can be successfully managed with early diagnosis and treatment.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Churg-Strauss Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Churg-Strauss Syndrome" returned 216 free, full-text research articles on human participants. First 3 results:

Crescentic glomerulonephritis in non-asthmatic Churg-Strauss syndrome.
 

Author(s): Anupma Kaul, Raj Kumar Sharma, Krishna Swamy Jaisuresh, Vinita Agrawal

Journal: Saudi J Kidney Dis Transpl. 2014 Mar;25(2):402-7.

 

A 58-year-old male presented with sensory motor polyneuropathy and rapidly progressive renal failure. Investigations revealed marked peripheral eosinophilia and elevated perinuclear antineutrophil cytoplasmic antibody titers. Renal biopsy showed pauci-immune cre-scentic glomerulonephritis ...

Last Updated: 14 Mar 2014

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A case of Churg-Strauss syndrome and central retinal artery occlusion with good visual recovery.
 

Author(s): Yuki Kamata, Kouhei Hashizume, Muneyoshi Kaneko, Daijiro Kurosaka

Journal: Indian J Ophthalmol. 2013 Apr;61(4):178-9.

 

Here we report a case of Churg-Strauss syndrome (CSS) and central retinal artery occlusion (CRAO), with good visual recovery. A 58-year-old Japanese man with CSS experienced acute painless loss of vision in his right eye. CRAO was diagnosed by fundoscopic findings (retinal whitening ...

Last Updated: 20 May 2013

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Eosinophilic myocarditis due to Churg-Strauss syndrome with markedly elevated eosinophil cationic protein.
 

Author(s): Tomoya Hara, Koji Yamaguchi, Takashi Iwase, Muneyuki Kadota, Mika Bando, Kozue Ogasawara, Sachiko Bando, Takayuki Ise, Toshiyuki Niki, Yuka Ueda, Noriko Tomita, Yoshio Taketani, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata

Journal: Int Heart J. 2013 ;54(1):51-3.

 

A 67-year-old woman with asthma visited our hospital with increasing dyspnea and new-onset paresthesia and purpura in her legs. Physical examination showed a wheeze, pretibial edema, and surrounding purpura. Chest X-rays showed cardiac decompensation and an electrocardiogram revealed ...

Last Updated: 22 Feb 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Churg-Strauss Syndrome" returned 16 free, full-text review articles on human participants. First 3 results:

Multiple cerebral and cerebellar infarcts as the first clinical manifestation in a patient with Churg-Strauss syndrome: case report and literature review.
 

Author(s): Meng-Ju Cheng, Pai-Hao Huang, Pin-Wen Liao, Jen-Tse Chen, Tsuey-Ru Chiang

Journal: Acta Neurol Taiwan. 2012 Dec;21(4):169-75.

 

Churg-Strauss syndrome (CSS) is a rare autoimmune disease with small-vessel vasculitis. Neurological manifestation of CSS is common. Central nervous system is less frequently involved than that of peripheral nervous system.

Last Updated: 18 Jan 2013

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Churg-Strauss syndrome presenting with acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis.
 

Author(s): Daigoro Hirohama, Junichi Hoshino, Keiichi Sumida, Eiko Hasegawa, Rikako Hiramatsu, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Naoki Sawa, Fumi Takemoto, Yoshifumi Ubara, Shigeko Hara, Kenichi Ohashi, Kenmei Takaichi

Journal: Intern. Med.. 2012 ;51(12):1555-60.

 

We encountered an unusual and rare case of 59-year-old woman with Churg-Strauss syndrome (CSS) showing myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-related acute renal insufficiency accompanied by eosinophilic tubulointerstitial nephritis. To date, reports in English ...

Last Updated: 25 Jun 2012

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Churg-Strauss syndrome complicated by chronic periaortitis: a case report and review of the literature.
 

Author(s): Kenji Fujii, Yuji Hidaka

Journal: Intern. Med.. 2012 ;51(1):109-12.

 

We present a case of Churg-Strauss syndrome complicated by chronic periaortitis. A 68-year-old man presented with wheezing, dyspnea, purpurae, and numbness of the extremities. Antineutrophil cytoplasmic antibodies were absent; however, eosinophilia, a pulmonary infiltrative shadow ...

Last Updated: 4 Jan 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Determining Disease Activity Biomarkers in Individuals With Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)
 

Status: Recruiting

Condition Summary: Eosinophilic Granulomatosis With Polyangiitis; Churg-Strauss Syndrome

 

Last Updated: 22 Nov 2013

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PRO Development for ANCA Associated Vasculitis
 

Status: Recruiting

Condition Summary: Wegener Granulomatosis; Microscopic Polyangiitis; Churg-Strauss Syndrome

 

Last Updated: 14 Nov 2012

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A Study to Investigate Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis
 

Status: Recruiting

Condition Summary: Churg-Strauss Syndrome

 

Last Updated: 24 Jul 2014

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