Chronic Myelomonocytic Leukemia

Common Name(s)

Chronic Myelomonocytic Leukemia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Myelomonocytic Leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Myelomonocytic Leukemia" returned 136 free, full-text research articles on human participants. First 3 results:

Transformation from atypical chronic myeloid leukemia to chronic myelomonocytic leukemia as progression of myeloid neoplasm with platelet-derived growth factor ß rearrangement.
 

Author(s): Xue Shi, Zhan Su, Chunting Zhao, Xianqi Feng

Journal: J Cancer Res Ther. ;11(4):914-6.

 

Myeloid neoplasms associated with platelet-derived growth factor b (PDGFRB) rearrangement usually keep only one morphologic type unless blast crisis. We describe a unique case of hematological features transformation from atypical chronic myeloid leukemia to chronic myelomonocytic ...

Last Updated: 17 Feb 2016

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Whole genome sequencing identified new somatic mutations for chronic myelomonocytic leukemia.
 

Author(s): Y Ying, J-J Xie, H-P Wang, P Mao, W Zhou, Z Yang, X-Y Chen

Journal: Eur Rev Med Pharmacol Sci. 2016 ;20(2):278-84.

 

We aimed to gain new insight into the molecular alterations of Chronic Myelomonocytic Leukemia (CMML).

Last Updated: 15 Feb 2016

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Prognostic interaction between ASXL1 and TET2 mutations in chronic myelomonocytic leukemia.
 

Author(s): M M Patnaik, T L Lasho, P Vijayvargiya, C M Finke, C A Hanson, R P Ketterling, N Gangat, A Tefferi

Journal:

 

Mutations involving epigenetic regulators (TET2~60% and ASXL1~40%) and splicing components (SRSF2~50%) are frequent in chronic myelomonocytic leukemia (CMML). On a 27-gene targeted capture panel performed on 175 CMML patients (66% males, median age 70 years), common mutations included: ...

Last Updated: 16 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Myelomonocytic Leukemia" returned 9 free, full-text review articles on human participants. First 3 results:

Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemia.
 

Author(s): M M Patnaik, A Tefferi

Journal:

 

Chronic myelomonocytic leukemia (CMML) is a clonal stem cell disorder associated with peripheral blood monocytosis and an inherent tendency to transform to acute myeloid leukemia. CMML has overlapping features of myelodysplastic syndromes and myeloproliferative neoplasms. Clonal cytogenetic ...

Last Updated: 6 Feb 2016

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Chronic myelomonocytic leukemia: Forefront of the field in 2015.
 

Author(s): Christopher B Benton, Aziz Nazha, Naveen Pemmaraju, Guillermo Garcia-Manero

Journal: Crit. Rev. Oncol. Hematol.. 2015 Aug;95(2):222-42.

 

Chronic myelomonocytic leukemia (CMML) includes components of both myelodysplastic syndrome and myeloproliferative neoplasms and is associated with a characteristic peripheral monocytosis. CMML is caused by the proliferation of an abnormal hematopoietic stem cell clone and may be ...

Last Updated: 18 Jul 2015

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Molecular genetics of chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia.
 

Author(s): Bing Li, Robert Peter Gale, Zhijian Xiao

Journal:

 

According to the 2008 World Health Organization classification, chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia are rare diseases. The remarkable progress in our understanding of the molecular genetics of myeloproliferative neoplasms ...

Last Updated: 18 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Expression of PTEN Protein and mRNA in Malignant Cells of Chronic Myelomonocytic Leukemia
 

Status: Recruiting

Condition Summary: Chronic Myelomonocytic Leukemia

 

Last Updated: 26 Aug 2016

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Study of Lenzilumab (KB003) in Previously Treated Patients With Chronic Myelomonocytic Leukemia (CMML)
 

Status: Recruiting

Condition Summary: Chronic Myelomonocytic Leukemia (CMML)

 

Last Updated: 25 Jul 2016

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Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia
 

Status: Recruiting

Condition Summary: Leukemia, Myelomonocytic, Chronic

 

Last Updated: 20 Oct 2016

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