Chronic Myelomonocytic Leukemia

Common Name(s)

Chronic Myelomonocytic Leukemia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Myelomonocytic Leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Myelomonocytic Leukemia" returned 146 free, full-text research articles on human participants. First 3 results:

Successful eltrombopag treatment of severe refractory thrombocytopenia in chronic myelomonocytic leukemia: Two cases reports: A CARE-compliant article.
 

Author(s): Yayue Gao, Ming Gong, Chunxia Zhang, Xudong Kong, Yigai Ma

Journal: Medicine (Baltimore). 2017 Oct;96(43):e8337.

 

Thrombocytopenia in chronic myelomonocytic leukemia (CMML) is usually attributed to impaired marrow production resulting from cytotoxic drug use or CMML itself ("CMML-induced thrombocytopenia"). In very rare cases, immune thrombocytopenia (ITP) can be a complication of CMML ("CMML-associated ...

Last Updated: 25 Oct 2017

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Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia.
 

Author(s): Yuan Ouyang, Chun Qiao, Yu Chen, Su-Jiang Zhang

Journal: Oncotarget. 2017 Mar;8(13):20834-20841.

 

Chronic neutrophilic leukemia (CNL) and chronic myelomonocytic leukemia (CMML) are rare hematologic neoplasms. We performed CSF3R, SRSF2 and SETBP1 mutational analyses in 10 CNL and 56 CMML patients. In this sample cohort, 80% of CNL patients harbored CSF3R mutations, of which the ...

Last Updated: 17 Feb 2017

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Prognostic significance of SETBP1 mutations in myelodysplastic syndromes, chronic myelomonocytic leukemia, and chronic neutrophilic leukemia: A meta-analysis.
 

Author(s): Li-Hong Shou, Dan Cao, Xiao-Hui Dong, Qiu Fang, Ying Wu, Yan Zhang, Ju-Ping Fei, Bao-Lian Xu

Journal:

 

This meta-analysis investigates the prognostic effect of SET binding protein 1 (SETBP1) mutations in patients with myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), or chronic neutrophilic leukemia (CNL).

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Myelomonocytic Leukemia" returned 12 free, full-text review articles on human participants. First 3 results:

When clinical heterogeneity exceeds genetic heterogeneity: thinking outside the genomic box in chronic myelomonocytic leukemia.
 

Author(s): Markus Ball, Alan F List, Eric Padron

Journal: Blood. 2016 Nov;128(20):2381-2387.

 

Exome sequencing studies in chronic myelomonocytic leukemia (CMML) illustrate a mutational landscape characterized by few somatic mutations involving a subset of recurrent gene mutations in ASXL1, SRSF2, and TET2, each approaching 40% in incidence. This has led to the clinical implementation ...

Last Updated: 6 Oct 2016

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Chronic myelomonocytic leukemia: 2016 update on diagnosis, risk stratification, and management.
 

Author(s): Mrinal M Patnaik, Ayalew Tefferi

Journal: Am. J. Hematol.. 2016 Jun;91(6):631-42.

 

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder characterized by overlapping features of myelodysplastic syndromes and myeloproliferative neoplasms. Diagnosis is based on the presence of persistent (>3 months) peripheral blood monocytosis (>1 × 10(9) ...

Last Updated: 17 May 2016

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Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemia.
 

Author(s): M M Patnaik, A Tefferi

Journal:

 

Chronic myelomonocytic leukemia (CMML) is a clonal stem cell disorder associated with peripheral blood monocytosis and an inherent tendency to transform to acute myeloid leukemia. CMML has overlapping features of myelodysplastic syndromes and myeloproliferative neoplasms. Clonal cytogenetic ...

Last Updated: 6 Feb 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Expression of PTEN Protein and mRNA in Malignant Cells of Chronic Myelomonocytic Leukemia
 

Status: Recruiting

Condition Summary: Chronic Myelomonocytic Leukemia

 

Last Updated: 30 Aug 2017

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Relevance of Peripheral Cells in the Pathophysiology of Chronic Myelomonocytic Leukemia (CMML)
 

Status: Recruiting

Condition Summary: Chronic Myelomonocytic Leukemia

 

Last Updated: 12 Sep 2017

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Study of Lenzilumab (KB003) in Previously Treated Patients With Chronic Myelomonocytic Leukemia (CMML)
 

Status: Recruiting

Condition Summary: Chronic Myelomonocytic Leukemia (CMML)

 

Last Updated: 13 Mar 2017

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