Chronic Myeloid Leukemia

Common Name(s)

Chronic Myeloid Leukemia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Myeloid Leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Myeloid Leukemia" returned 1198 free, full-text research articles on human participants. First 3 results:

Intracerebral Granulocytic Sarcoma in recurrence of Chronic Myeloid Leukemia.
 

Author(s): Angelo Borsarelli Carvalho Brito, Fabiano Reis, Ana Laura Gatti Palma, Carmen Silvia Passos Lima

Journal: Arq Neuropsiquiatr. 2015 Jan;73(1):68.

 

Last Updated: 22 Jan 2015

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Molecular response to nilotinib in a patient with imatinib-intolerant e19a2-positive chronic myeloid leukemia.
 

Author(s): Tomohiro Kajiguchi, Shingo Okuno, Toshihito Ohno, Akihiro Abe

Journal: Intern. Med.. 2014 ;53(24):2801-4.

 

The BCR-ABL1 fusion gene is the molecular marker of chronic myeloid leukemia (CML). The e19a2 transcript is a rare variant associated with various clinical presentations and courses of CML. We herein present a case of e19a2-positive CML who was intolerant to initial treatment with ...

Last Updated: 16 Dec 2014

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CAT, GPX1, MnSOD, GSTM1, GSTT1, and GSTP1 genetic polymorphisms in chronic myeloid leukemia: a case-control study.
 

Author(s): Claudia Bănescu, Adrian P Trifa, Septimiu Voidăzan, Valeriu G Moldovan, Ioan Macarie, Erzsebeth Benedek Lazar, Delia Dima, Carmen Duicu, Minodora Dobreanu

Journal: Oxid Med Cell Longev. 2014 ;2014():875861.

 

Oxidative damage at the DNA level may be promoted by high levels of reactive oxygen species (ROS), leading to genomic instability and increased neoplastic risk. Superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) enzymes are implicated in the prevention of ...

Last Updated: 1 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Myeloid Leukemia" returned 141 free, full-text review articles on human participants. First 3 results:

Molecular genetics of chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia.
 

Author(s): Bing Li, Robert Peter Gale, Zhijian Xiao

Journal:

 

According to the 2008 World Health Organization classification, chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia are rare diseases. The remarkable progress in our understanding of the molecular genetics of myeloproliferative neoplasms ...

Last Updated: 18 Dec 2014

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[Bone marrow microenvironment in chronic myeloid leukemia: implications for disease physiopathology and response to treatment].
 

Author(s): José Alejandro Aristizábal, Mauricio Chandia, María Consuelo Del Cañizo, Fermín Sánchez-Guijo

Journal: Rev Med Chil. 2014 May;142(5):599-605.

 

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm related to the presence of the BCR-ABL1 fusion gene, linked to t (9;22) (q34;q11). It is originated from an abnormal hematopoietic stem cell, which is characterized as its normal counterparts by long-term self-renewal ...

Last Updated: 27 Nov 2014

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[Chronic myeloid leukemia stem cells: cross-talk with the niche].
 

Author(s): Jean-Claude Chomel, Djamel Aggoune, Nathalie Sorel, Ali G Turhan

Journal: Med Sci (Paris). 2014 Apr;30(4):452-61.

 

The physiological hematopoietic niche located in bone marrow is a pluricellular structure whose components are now well identified. Within this microenvironment, hematopoietic stem cells are in direct contact with mesenchymal stromal cells, osteoblasts and sinusoidal endothelial cells. ...

Last Updated: 7 May 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Front-line Nilotinib Treatment of BCR-ABL+ Chronic Myeloid Leukaemia in Chronic Phase
 

Status: Recruiting

Condition Summary: Chronic Phase Philadelphia Positive; BCR-ABL Positive; Chronic Myeloid Leukaemia

 

Last Updated: 22 Feb 2015

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Pulmonary Vasculopathy Under Second-line Therapy of Chronic Myeloid Leukemia
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia

 

Last Updated: 23 Nov 2014

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Front-line Treatment of BCR-ABL+ Chronic Myeloid Leukemia (CML) With Dasatinib
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia

 

Last Updated: 26 May 2015

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