Chronic Myeloid Leukemia

Common Name(s)

Chronic Myeloid Leukemia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Myeloid Leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Myeloid Leukemia" returned 1106 free, full-text research articles on human participants. First 3 results:

Characterization of miRNomes in acute and chronic myeloid leukemia cell lines.
 

Author(s): Qian Xiong, Yadong Yang, Hai Wang, Jie Li, Shaobin Wang, Yanming Li, Yaran Yang, Kan Cai, Xiuyan Ruan, Jiangwei Yan, Songnian Hu, Xiangdong Fang

Journal: Genomics Proteomics Bioinformatics. 2014 Apr;12(2):79-91.

 

Myeloid leukemias are highly diverse diseases and have been shown to be associated with microRNA (miRNA) expression aberrations. The present study involved an in-depth miRNome analysis of two human acute myeloid leukemia (AML) cell lines, HL-60 and THP-1, and one human chronic myeloid ...

Last Updated: 20 May 2014

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Older patients with chronic myeloid leukemia (≥65 years) profit more from higher imatinib doses than younger patients: a subanalysis of the randomized CML-Study IV.
 

Author(s): Ulrike Proetel, Nadine Pletsch, Michael Lauseker, Martin C Müller, Benjamin Hanfstein, Stefan W Krause, Lida Kalmanti, Annette Schreiber, Dominik Heim, Gabriela M Baerlocher, Wolf-Karsten Hofmann, Elisabeth Lange, Hermann Einsele, Martin Wernli, Stephan Kremers, Rudolf Schlag, Lothar Müller, Mathias Hänel, Hartmut Link, Bernd Hertenstein, Markus Pfirrman, Andreas Hochhaus, Joerg Hasford, Rüdiger Hehlmann, Susanne Saußele, ,

Journal: Ann. Hematol.. 2014 Jul;93(7):1167-76.

 

The impact of imatinib dose on response rates and survival in older patients with chronic myeloid leukemia in chronic phase has not been studied well. We analyzed data from the German CML-Study IV, a randomized five-arm treatment optimization study in newly diagnosed BCR-ABL-positive ...

Last Updated: 17 Jul 2014

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The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia.
 

Author(s): Adam L MacLean, Sarah Filippi, Michael P H Stumpf

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Mar;111(10):3883-8.

 

Chronic myeloid leukemia (CML) is a blood disease that disrupts normal function of the hematopoietic system. Despite the great progress made in terms of molecular therapies for CML, there remain large gaps in our understanding. By comparing mathematical models that describe CML progression ...

Last Updated: 12 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Myeloid Leukemia" returned 126 free, full-text review articles on human participants. First 3 results:

Moving towards patient-centered decision-making in chronic myeloid leukemia: assessment of quality of life and symptom burden.
 

Author(s): Michele Baccarani, Fabio Efficace, Gianantonio Rosti

Journal: Haematologica. 2014 Feb;99(2):205-8.

 

Last Updated: 5 Feb 2014

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Dasatinib-responsive chronic lymphocytic leukemia in a patient treated for coexisting chronic myeloid leukemia.
 

Author(s): Takayo Nagao, Naoto Takahashi, Yoshihiro Kameoka, Shinsuke Noguchi, Yoshinori Shinohara, Hideaki Ohyagi, Masaaki Kume, Kenichi Sawada

Journal: Intern. Med.. 2013 ;52(22):2567-71.

 

We herein present a case of concurrent chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL). Two different clones, a Philadelphia (Ph) clone and a CLL clone with a 13q deletion, were identified using fluorescent in situ hybridization. Dasatinib was administered to ...

Last Updated: 18 Nov 2013

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Implications of BCR-ABL1 kinase domain-mediated resistance in chronic myeloid leukemia.
 

Author(s): Simona Soverini, Susan Branford, Franck E Nicolini, Moshe Talpaz, Michael W N Deininger, Giovanni Martinelli, Martin C Müller, Jerald P Radich, Neil P Shah

Journal: Leuk. Res.. 2014 Jan;38(1):10-20.

 

Patients with chronic myeloid leukemia develop resistance to both first-generation and second-generation tyrosine kinase inhibitors (TKIs) as a result of mutations in the kinase domain (KD) of BCR-ABL1. A wide range of BCR-ABL1 KD mutations that confer resistance to TKIs have been ...

Last Updated: 23 Dec 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Front-line Nilotinib Treatment of BCR-ABL+ Chronic Myeloid Leukaemia in Chronic Phase
 

Status: Recruiting

Condition Summary: Chronic Phase Philadelphia Positive; BCR-ABL Positive; Chronic Myeloid Leukaemia

 

Last Updated: 12 May 2014

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Pulmonary Vasculopathy Under Second-line Therapy of Chronic Myeloid Leukemia
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia

 

Last Updated: 18 Feb 2014

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Front-line Treatment of BCR-ABL+ Chronic Myeloid Leukemia (CML) With Dasatinib
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia

 

Last Updated: 30 Jan 2014

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