Chronic Myeloid Leukemia

Common Name(s)

Chronic Myeloid Leukemia

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Myeloid Leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Myeloid Leukemia" returned 1352 free, full-text research articles on human participants. First 3 results:

Major progress in understanding progression in chronic myeloid leukemia.
 

Author(s): Jerry Radich

Journal: J. Exp. Med.. 2015 Sep;212(10):1482.

 

Last Updated: 22 Sep 2015

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Inclusion body myositis in a patient with chronic myeloid leukemia treated with dasatinib: a case report.
 

Author(s): Naif I AlJohani, Simon Carette, Jeffrey H Lipton

Journal:

 

Chronic myelogenous leukemia is often treated using tyrosine kinase inhibitors such as dasatinib. Here we describe a rare case of inflammatory myopathy in a patient with chronic myelogenous leukemia treated with the tyrosine kinase inhibitor dasatinib.

Last Updated: 17 Sep 2015

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A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.
 

Author(s): George Giotopoulos, Louise van der Weyden, Hikari Osaki, Alistair G Rust, Paolo Gallipoli, Eshwar Meduri, Sarah J Horton, Wai-In Chan, Donna Foster, Rab K Prinjha, John E Pimanda, Daniel G Tenen, George S Vassiliou, Steffen Koschmieder, David J Adams, Brian J P Huntly

Journal: J. Exp. Med.. 2015 Sep;212(10):1551-69.

 

The introduction of highly selective ABL-tyrosine kinase inhibitors (TKIs) has revolutionized therapy for chronic myeloid leukemia (CML). However, TKIs are only efficacious in the chronic phase of the disease and effective therapies for TKI-refractory CML, or after progression to ...

Last Updated: 22 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Myeloid Leukemia" returned 141 free, full-text review articles on human participants. First 3 results:

Evaluation of a father and son with atypical chronic myeloid leukemia with SETBP1 mutations and a review of the literature.
 

Author(s): L Wang, F Du, H-M Zhang, H-X Wang

Journal: Braz. J. Med. Biol. Res.. 2015 Jul;48(7):583-7.

 

We report the case of a father and son diagnosed with atypical chronic myeloid leukemia (aCML). Both patients harbored SETBP1 mutations, which are present in 24.3% of aCML patients. Moreover, both shared the variant encoding p.Pro737His, but the aCML severity was greater in the son ...

Last Updated: 9 Jul 2015

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Diagnosing and managing advanced chronic myeloid leukemia.
 

Author(s): Michael W Deininger

Journal: Am Soc Clin Oncol Educ Book. 2015 ;():e381-8.

 

Clinical staging of chronic myeloid leukemia (CML) distinguishes between chronic phase (CP-CML), accelerated phase (AP-CML), and blastic phase (BP-CML), reflecting its natural history in the absence of effective therapy. Morphologically, transformation from CP-CML to AP/BP-CML is ...

Last Updated: 21 May 2015

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Hematopoietic cell transplantation in chronic myeloid leukemia in the age of tyrosine kinase inhibitors.
 

Author(s): Edward A Copelan, Michael R Grunwald, Nilanjan Ghosh, Dragos Plesca, Jigar Trivedi, Belinda R Avalos

Journal: Discov Med. 2015 Mar;19(104):213-8.

 

The development and widespread use of tyrosine kinase inhibitors (TKIs) has relegated the use of hematopoietic cell transplant (HCT), in most countries, to chronic myeloid leukemia (CML) patients who fail or are intolerant to TKIs. Its long-term cost effectiveness compared to TKIs, ...

Last Updated: 1 Apr 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Front-line Nilotinib Treatment of BCR-ABL+ Chronic Myeloid Leukaemia in Chronic Phase
 

Status: Recruiting

Condition Summary: Chronic Phase Philadelphia Positive; BCR-ABL Positive; Chronic Myeloid Leukaemia

 

Last Updated: 22 Feb 2015

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Front-line Treatment of BCR-ABL+ Chronic Myeloid Leukemia (CML) With Dasatinib
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia

 

Last Updated: 26 May 2015

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TyrosIne Kinase Inhibitors in Chronic Myeloid Leukemia: Efficacy and Tolerability. The TIKlet Study
 

Status: Recruiting

Condition Summary: Chronic Myeloid Leukemia

 

Last Updated: 18 May 2013

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