Chronic Inflammatory Demyelinating Polyneuropathy

Common Name(s)

Chronic Inflammatory Demyelinating Polyneuropathy

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a neurological disorder characterized by progressive weakness and impaired sensory function in the legs and arms. The disorder is caused by damage to the myelin sheath (the fatty covering that wraps around and protects nerve fibers) of the peripheral nerves. It often presents with symptoms that include tingling or numbness (beginning in the toes and fingers), weakness of the arms and legs, loss of deep tendon reflexes, fatigue, and abnormal sensations. CIDP is closely related to Guillain-Barre syndrome and it is considered the chronic counterpart of that acute disease. Treatment may include corticosteroids, immunosuppressant drugs, plasma exchange, physiotherapy, and/or intravenous immunoglobulin (IVIg) therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Inflammatory Demyelinating Polyneuropathy" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

Last Updated: 19 Feb 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

Last Updated: 5 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Inflammatory Demyelinating Polyneuropathy" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
GBS/CIDP Foundation International

To improve the quality of life for individuals and families worldwide affected by GBS, CIDP and variants by: Providing a network for all patients, their caregivers and families so that GBS or CIDP patients can depend on the Foundation for support, and reliable up-to-date information. Providing public and professional educational programs worldwide designed to heighten awareness and improve the understanding and treatment of GBS, CIDP and variants. Expanding the Foundation’s role in sponsoring research and engaging in patient advocacy.

http://www.gbs-cidp.org

Last Updated: 19 Feb 2013

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stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Inflammatory Demyelinating Polyneuropathy" returned 85 free, full-text research articles on human participants. First 3 results:

Chronic inflammatory demyelinating polyneuropathy (CIDP): change of serum IgG dimer levels during treatment with intravenous immunoglobulins.
 

Author(s): Christian Ritter, Ilja Bobylev, Helmar C Lehmann

Journal:

 

Intravenous immunoglobulin (IVIg) is an effective treatment in chronic inflammatory demyelinating polyneuropathy (CIDP). In most patients, the optimal IVIg dose and regime is unknown. Polyvalent immunoglobulin (Ig) G form idiotypic/anti-idiotypic antibody pairs in serum and IVIg preparations. ...

Last Updated: 13 Aug 2015

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Trigeminal nerve thickening in chronic inflammatory demyelinating polyneuropathy.
 

Author(s): Bruno Fukelmann Guedes, Rubens Gisbert Cury

Journal: Arq Neuropsiquiatr. 2015 Jul;73(7):634-5.

 

Last Updated: 23 Jul 2015

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Chronic inflammatory demyelinating polyneuropathy-like neuropathy as an initial presentation of Crohn's disease.
 

Author(s): Suji Kim, Seok-Jae Kang, Ki-Wook Oh, Byung Kyu Ahn, Hang Lak Lee, Dong Soo Han, Kiseok Jang, Young Seo Kim

Journal:

 

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare complication of Crohn's disease (CD), and it is uncertain whether it is associated with CD itself or with its treatment. We describe a case of CIDP-like neuropathy as an initial symptom of CD. The neurologic symptoms ...

Last Updated: 18 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Inflammatory Demyelinating Polyneuropathy" returned 3 free, full-text review articles on human participants. First 3 results:

Office immunotherapy in chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy.
 

Author(s): Peter J Dyck, Bruce V Taylor, Jenny L Davies, Michelle L Mauermann, William J Litchy, Christopher J Klein, P James B Dyck

Journal: Muscle Nerve. 2015 Oct;52(4):488-97.

 

Intravenous immunoglobulin [IVIg], plasma exchange [PE], and corticosteroids are efficacious treatment in chronic inflammatory demyelinating polyneuropathy [CIDP]. IVIg is effective in multifocal motor neuropathy [MMN]. NIS, NIS-weakness, sum scores of raw amplitudes of motor fiber ...

Last Updated: 23 Sep 2015

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[Recent aspects of acute and chronic inflammatory polyneuropathies: Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy].
 

Author(s): S I Pascual-Pascual

Journal: Rev Neurol. ;35(3):269-76.

 

In last decade many advances have occurred in knowledge of pathogenic, in the different types of clinic expression and in the therapy of both acute and chronic polyneuritis.

Last Updated: 17 Sep 2002

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Intravenous immunoglobulin treatment in patients with chronic inflammatory demyelinating polyneuropathy.
 

Author(s): P A van Doorn

Journal: J. Neurol. Neurosurg. Psychiatr.. 1994 Nov;57 Suppl():38-42.

 

Intravenous immunoglobulin (IVIg) treatment is shown to be effective in a selected group of patients with a chronic inflammatory demyelinating polyneuropathy (CIDP). The proportion of patients that improve after IVIg treatment varies between studies. Because 40% of a group of IVIg ...

Last Updated: 21 Dec 1994

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Subcutaneous Immunoglobulin for CIDP
 

Status: Recruiting

Condition Summary: Chronic Inflammatory Demyelinating Polyneuropathy

 

Last Updated: 29 Jul 2016

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IVIg Treatment-Related Fluctuations in CIDP Patients Using Daily Grip Strength Measurements
 

Status: Recruiting

Condition Summary: Chronic Inflammatory Demyelinating Polyneuropathy

 

Last Updated: 23 Jun 2016

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Last Updated: 7 Sep 2016

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