Acromegaly

Common Name(s)

Acromegaly

Acromegaly is a hormonal disorder that results from the pituitary gland producing too much growth hormone (GH). It is most often diagnosed in middle-aged adults, although symptoms can appear at any age. Signs and symptoms include abnormal growth and swelling of the hands and feet; bone changes that alter various facial features; arthritis; carpal tunnel syndrome; enlargement of body organs; and various other symptoms. The condition is usually caused by benign tumors on the pituitary called adenomas. Rarely, it is caused by tumors of the pancreas, lungs, and other parts of the brain. Acromegaly is usually treatable but when left untreated, it can result in serious illness and premature death. When GH-producing tumors occur in childhood, the disease that results is called gigantism rather than acromegaly.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acromegaly" for support, advocacy or research.

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Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acromegaly" for support, advocacy or research.

Logo
Pituitary Network Association

To support, pursue, encourage, promote, and, where possible, fund research on pituitary disorders in a sustained and full-time effort to find a cure for these illnesses. The PNA will disseminate information helpful to the medical community, the public, and to pituitary patients and their families on matters regarding early detection, symptoms, treatments and resources available to patients with pituitary disease.

http://www.pituitary.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acromegaly" returned 655 free, full-text research articles on human participants. First 3 results:

A Case of Acromegaly in which a Pituitary Gland Tumor was Reduced Significantly by Administering Octreotide Long Acting Release (LAR) and Could Be Removed Surgically.
 

Author(s): Tadashi Arao, Yosuke Okada, Fumi Uemura, Shigeru Nishizawa, Yoshiya Tanaka

Journal: J. UOEH. ;39(3):241-245.

 

A 54-year-old woman was admitted to our hospital for detailed examination of acromegaly because she noticed bilateral hand and finger swelling at the age of 43 and plantar thickening, facial changes and unclear articulation at the age of 49. She had prominent brow ridges, mandibular ...

Last Updated: 31 Dec 1969

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Prevalence of acromegaly in patients with symptoms of sleep apnea.
 

Author(s): Gemma Sesmilo, Eugenia Resmini, Marcel Sambo, Concepción Blanco, Fernando Calvo, Fernando Pazos, Pablo Fernández-Catalina, Purificación Martínez de Icaya, Concepción Páramo, Carmen Fajardo, Mónica Marazuela, Cristina Álvarez-Escolá, Juan Jose Díez, Verónica Perea,

Journal:

 

Acromegaly is a rare disease with nonspecific symptoms with acral enlargement being almost universally present at diagnosis. The estimated prevalence is 40-125 cases/million but targeted universal screening studies have found a higher prevalence (about 10 fold). The aim of the ACROSAHS ...

Last Updated: 31 Dec 1969

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Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report.
 

Author(s): Maria de Fátima Borges, Beatriz Hallal Jorge Lara, Janaíne Machado Tomé, Leopoldo Prezia de Araújo, Flávio Cesar Lucas Bugiga, Júlio Cláudio Sousa, Jacqueline Mendes Fonseca Soares, Roberto Alexandre Dezena, Beatriz Pires Ferreira

Journal: Clinics (Sao Paulo). 2017 Apr;72(4):218-223.

 

To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acromegaly" returned 87 free, full-text review articles on human participants. First 3 results:

[Acromegaly features in the aging population].
 

Author(s): Nadia Anoun, Hanan El Ouahabi

Journal:

 

Somatotroph adenomas are rare in the aging population. Diagnosis of somatotroph adenomas is often long delayed and they are characterized by atypical clinical picture. Their diagnostic criteria are similar to those used for younger patients. Surgery, if possible, is the treatment ...

Last Updated: 31 Dec 1969

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Cardiovascular Disease in Acromegaly.
 

Author(s): Morali D Sharma, Anh V Nguyen, Spandana Brown, Richard J Robbins

Journal: Methodist Debakey Cardiovasc J. ;13(2):64-67.

 

In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and ...

Last Updated: 31 Dec 1969

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MANAGEMENT OF ENDOCRINE DISEASE: Acromegaly and pregnancy: a contemporary review.
 

Author(s): Julio Abucham, Marcello D Bronstein, Monike L Dias

Journal: Eur. J. Endocrinol.. 2017 Jul;177(1):R1-R12.

 

Although fertility is frequently impaired in women with acromegaly, pregnancy is apparently becoming more common due to improvement in acromegaly treatment as well as in fertility therapy. As a result, several studies on pregnancy in patients with acromegaly have been published in ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 22 May 2017

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Treatment Patterns and Treatment Outcomes for Acromegaly
 

Status: Recruiting

Condition Summary: Acromegaly

 

Last Updated: 2 Feb 2017

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A Prospective Study of Outcome After Therapy for Acromegaly
 

Status: Recruiting

Condition Summary: Acromegaly

 

Last Updated: 2 Feb 2017

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