Chromosome 9

Common Name(s)

Chromosome 9

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chromosome 9" for support, advocacy or research.

Chromosome 9 Disorder Advocates

Changing the world one chromosome and one hope at a time. We are your voice and your direction if ever you feel speechless or lost.

Last Updated: 15 May 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chromosome 9" for support, advocacy or research.

Chromosome 9 Disorder Advocates

Changing the world one chromosome and one hope at a time. We are your voice and your direction if ever you feel speechless or lost.

http://www.facebook.com/9qdeletion

Last Updated: 15 May 2015

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General Support Organizations

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General Resources

46,XY,del(9)(q31.2q33.1)

Single case chromosome disorder in 9

Updated 27 Nov 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chromosome 9" returned 195 free, full-text research articles on human participants. First 3 results:

Pericentric Inversion of Human Chromosome 9 Epidemiology Study in Czech Males and Females.
 

Author(s): A Šípek, A Panczak, R Mihalová, L Hrčková, E Suttrová, V Sobotka, P Lonský, N Kaspříková, V Gregor

Journal: Folia Biol. (Praha). 2015 ;61(4):140-6.

 

Pericentric inversion of human chromosome 9 [inv(9)] is a relatively common cytogenetic finding. It is largely considered a clinically insignificant variant of the normal human karyotype. However, numerous studies have suggested its possible association with certain pathologies, e.g., ...

Last Updated: 7 Oct 2015

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Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome.
 

Author(s): Nicholas J Brideau, Heather Coker, Anne-Valerie Gendrel, C Alistair Siebert, Karel Bezstarosti, Jeroen Demmers, Raymond A Poot, Tatyana B Nesterova, Neil Brockdorff

Journal: Mol. Cell. Biol.. 2015 Dec;35(23):4053-68.

 

The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted genes, and the facioscapulohumeral muscular dystrophy locus. Although homology with canonical SMC family proteins suggests a role in chromosome ...

Last Updated: 31 Oct 2015

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The functional interplay between the t(9;22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia.
 

Author(s): Anahita Rafiei, Afsar Ali Mian, Claudia Döring, Anna Metodieva, Claudia Oancea, Frederic B Thalheimer, Martin Leo Hansmann, Oliver Gerhard Ottmann, Martin Ruthardt

Journal:

 

The hallmark of Philadelphia chromosome positive (Ph(+)) leukemia is the BCR/ABL kinase, which is successfully targeted by selective ATP competitors. However, inhibition of BCR/ABL alone is unable to eradicate Ph(+) leukemia. The t(9;22) is a reciprocal translocation which encodes ...

Last Updated: 29 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chromosome 9" returned 4 free, full-text review articles on human participants. First 3 results:

Double jeopardy from a single translocation: deletions of the derivative chromosome 9 in chronic myeloid leukemia.
 

Author(s): Brian J P Huntly, Anthony Bench, Anthony R Green

Journal: Blood. 2003 Aug;102(4):1160-8.

 

Chronic myeloid leukemia (CML) is characterized by formation of a BCR-ABL fusion gene, usually as a consequence of the Philadelphia (Ph) translocation between chromosomes 9 and 22. Recently the development of new fluorescence in-situ hybridization (FISH) techniques has allowed identification ...

Last Updated: 5 Aug 2003

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A comparative approach to physical and linkage mapping of genes on canine chromosomes using gene-associated simple sequence repeat polymorphisms illustrated by studies of dog chromosome 9.
 

Author(s): P Werner, M G Raducha, U Prociuk, P S Henthorn, D F Patterson

Journal: J. Hered.. ;90(1):39-42.

 

We describe and illustrate a comparative approach to creating physical and linkage maps of genes on dog chromosomes. The approach is particularly useful in species, like the dog, which have a rudimentary gene map not integrated with microsatellite loci. Human or mouse cDNAs for genes ...

Last Updated: 18 Mar 1999

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALS
 

Status: Recruiting

Condition Summary: C9ORF72 Amyotrophic Lateral Sclerosis (ALS)

 

Last Updated: 8 Mar 2016

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Online Study of Individuals With Genetic Changes and Features of Autism: Simons Variation in Individuals Project (Simons VIP)
 

Status: Recruiting

Condition Summary: 16p11.2 Deletions; 16p11.2 Duplications; 1q21.1 Deletions; 1q21.1 Duplications; ADNP (ADNP1, KIAA0784); ANKRD1 (ANCO1, T13, LZ16); ARID1B (BAF250B); ASXL3 (KIAA1713); BAF105; BAF180 (PBRM1, PB1); BAF190 (SMARCA4/SMARCA2); BAF35 (BCL7B); BAF35b (ACTL6B); BCL11A (CTIP1, EVI9, KIAA1809, FLJ10173); CHD2; CHD8 (KIAA1564, DUPLIN); CTNNB1 (CTNNB); CUL3 (Cullin 3, PHA2E, KIAA0617); DST (BPAG1, BP240); DYRK1A; FOXP1 (QRF1); GRIN2B (NMDAR2B, NR2B); KDM6B (JMJD3, KIAA0346); KMT2E (MLL5); MBD5 (KIAA1461); MED13L (THRAP2, PROSIT240, TRAP240L, KIAA1025); PTEN (PTEN1, MMAC1); REST (NRSF); SCN2A; SMARCC1 (BAF155); SMARCC2 (BAF170); SYNGAP1; Additional Genetic Changes Associated With Autism May be Added as Identified

 

Last Updated: 16 Nov 2015

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Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma
 

Status: Recruiting

Condition Summary: Adult B Lymphoblastic Lymphoma; Childhood B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34;q11.2); BCR-ABL1; Childhood B Lymphoblastic Lymphoma; Down Syndrome; Stage I B Lymphoblastic Lymphoma; Stage II B Lymphoblastic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia

 

Last Updated: 18 Mar 2016

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