Chromosome 8p

Common Name(s)

Chromosome 8p

Description for this condition is not yet available.
 

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Condition Specific Organizations

Following organizations serve the condition "Chromosome 8p" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chromosome 8p" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chromosome 8p" returned 45 free, full-text research articles on human participants. First 3 results:

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma.
 

Author(s): Carolin Ploeger, Nina Waldburger, Angelika Fraas, Benjamin Goeppert, Stefan Pusch, Kai Breuhahn, Xin Wei Wang, Peter Schirmacher, Stephanie Roessler

Journal: Hepatology. 2016 Sep;64(3):828-42.

 

Several chronic inflammatory liver diseases, e.g., chronic hepatitis B or C viral infection and steatohepatitis, have been shown to predispose to the development of hepatocellular carcinoma (HCC). In patients with chronic liver disease, interleukin-6 (IL-6) serum levels are elevated ...

Last Updated: 20 Aug 2016

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Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism.
 

Author(s): Yanyan Cai, Jonathan Crowther, Tibor Pastor, Layka Abbasi Asbagh, Maria Francesca Baietti, Magdalena De Troyer, Iria Vazquez, Ali Talebi, Fabrizio Renzi, Jonas Dehairs, Johannes V Swinnen, Anna A Sablina

Journal: Cancer Cell. 2016 05;29(5):751-766.

 

Large-scale heterozygous deletions are a hallmark of cancer genomes. The concomitant loss of multiple genes creates vulnerabilities that are impossible to reveal through the study of individual genes. To delineate the functional outcome of chromosome 8p loss of heterozygosity (LOH), ...

Last Updated: 11 May 2016

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Coordinated Tumor Suppression by Chromosome 8p.
 

Author(s): Darjus F Tschaharganeh, Benedikt Bosbach, Scott W Lowe

Journal: Cancer Cell. 2016 05;29(5):617-619.

 

In this issue of Cancer Cell, Cai et al. use genome editing to study 8p deletions in a mammary epithelial cell model and show that 8p loss of heterozygosity (LOH) attenuates the action of several genes that collectively promote cell invasion and enhance cellular sensitivity to autophagy ...

Last Updated: 11 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chromosome 8p" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.