Chromosome 22

Common Name(s)

Chromosome 22

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chromosome 22" for support, advocacy or research.

Chromosome 22 Central

Our mission is to provide support and information to families or individuals affected by disorders of chromosome 22.

Last Updated: 11 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chromosome 22" for support, advocacy or research.

Chromosome 22 Central

Our mission is to provide support and information to families or individuals affected by disorders of chromosome 22.

http://www.c22c.org

Last Updated: 11 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chromosome 22" returned 163 free, full-text research articles on human participants. First 3 results:

Functional annotation of proteome encoded by human chromosome 22.
 

Author(s): Sneha M Pinto, Srikanth S Manda, Min-Sik Kim, KyOnese Taylor, Lakshmi Dhevi Nagarajha Selvan, Lavanya Balakrishnan, Tejaswini Subbannayya, Fangfei Yan, T S Keshava Prasad, Harsha Gowda, Charles Lee, William S Hancock, Akhilesh Pandey

Journal: J. Proteome Res.. 2014 Jun;13(6):2749-60.

 

As part of the chromosome-centric human proteome project (C-HPP) initiative, we report our progress on the annotation of chromosome 22. Chromosome 22, spanning 51 million base pairs, was the first chromosome to be sequenced. Gene dosage alterations on this chromosome have been shown ...

Last Updated: 6 Jun 2014

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The emerging role of genomics in the diagnosis and workup of congenital urinary tract defects: a novel deletion syndrome on chromosome 3q13.31-22.1.
 

Author(s): Anna Materna-Kiryluk, Krzysztof Kiryluk, Katelyn E Burgess, Arkadiusz Bieleninik, Simone Sanna-Cherchi, Ali G Gharavi, Anna Latos-Bielenska

Journal: Pediatr. Nephrol.. 2014 Feb;29(2):257-67.

 

Copy number variants (CNVs) are increasingly recognized as an important cause of congenital malformations and likely explain over 16% of cases of congenital anomalies of the kidney and urinary tract (CAKUT). Here, we illustrate how a molecular diagnosis of CNV can be beneficial to ...

Last Updated: 3 Jan 2014

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The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22.
 

Author(s): Massimo Pancione, Andrea Remo, Caterina Zanella, Lina Sabatino, Arturo Di Blasi, Carmelo Laudanna, Laura Astati, Michele Rocco, Delfina Bifano, Paolo Piacentini, Laura Pavan, Alberto Purgato, Filippo Greco, Alberto Talamini, Andrea Bonetti, Michele Ceccarelli, Roberto Vendraminelli, Erminia Manfrin, Vittorio Colantuoni

Journal:

 

INI1 (Integrase interactor 1), also known as SMARCB1, is the most studied subunit of chromatin remodelling complexes. Its role in colorectal tumorigenesis is not known.

Last Updated: 11 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chromosome 22" returned 3 free, full-text review articles on human participants. First 3 results:

Constitutional rearrangements of chromosome 22 as a cause of neurofibromatosis 2.
 

Author(s): T Tsilchorozidou, F H Menko, F Lalloo, A Kidd, R De Silva, H Thomas, P Smith, A Malcolmson, J Dore, K Madan, A Brown, J G Yovos, M Tsaligopoulos, N Vogiatzis, M E Baser, A J Wallace, D G R Evans

Journal: J. Med. Genet.. 2004 Jul;41(7):529-34.

 

Last Updated: 5 Jul 2004

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Partial trisomy of chromosome 22 resulting from an interstitial duplication of 22q11.2 in a child with typical cat eye syndrome.
 

Author(s): M Meins, P Burfeind, S Motsch, R Trappe, D Bartmus, S Langer, M R Speicher, H Mühlendyck, I Bartels, B Zoll

Journal: J. Med. Genet.. 2003 May;40(5):e62.

 

Last Updated: 14 May 2003

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Human chromosome 22.
 

Author(s): J C Kaplan, A Aurias, C Julier, M Prieur, M F Szajnert

Journal: J. Med. Genet.. 1987 Feb;24(2):65-78.

 

The acrocentric chromosome 22, one of the shortest human chromosomes, carries about 52 000 kb of DNA. The short arm is made up essentially of heterochromatin and, as in other acrocentric chromosomes, it contains ribosomal RNA genes. Ten identified genes have been assigned to the long ...

Last Updated: 20 May 1987

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetics and Psychopathology in the 22q11 Deletion Syndrome
 

Status: Recruiting

Condition Summary: Chromosome 22q11.2 Deletion Syndrome

 

Last Updated: 12 Oct 2006

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SNP-based Microdeletion and Aneuploidy RegisTry (SMART)
 

Status: Not yet recruiting

Condition Summary: 22q11 Deletion Syndrome; DiGeorge Syndrome; Trisomy 21; Trisomy 18; Trisomy 13; Monosomy X; Sex Chromosome Abnormalities; Cri-du-Chat Syndrome; Angelman Syndrome; Prader-Willi Syndrome; 1p36 Deletion Syndrome

 

Last Updated: 2 Mar 2015

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