Chromosome 16

Common Name(s)

Chromosome 16

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chromosome 16" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chromosome 16" returned 152 free, full-text research articles on human participants. First 3 results:

Overlapping trisomies for human chromosome 21 orthologs produce similar effects on skull and brain morphology of Dp(16)1Yey and Ts65Dn mice.
 

Author(s): John M Starbuck, Tara Dutka, Tabetha S Ratliff, Roger H Reeves, Joan T Richtsmeier

Journal: Am. J. Med. Genet. A. 2014 Aug;164A(8):1981-90.

 

Trisomy 21 results in gene-dosage imbalance during embryogenesis and throughout life, ultimately causing multiple anomalies that contribute to the clinical manifestations of Down syndrome. Down syndrome is associated with manifestations of variable severity (e.g., heart anomalies, ...

Last Updated: 21 Jul 2014

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Positive selection in the chromosome 16 VKORC1 genomic region has contributed to the variability of anticoagulant response in humans.
 

Author(s): Blandine Patillon, Pierre Luisi, Hélène Blanché, Etienne Patin, Howard M Cann, Emmanuelle Génin, Audrey Sabbagh

Journal: PLoS ONE. 2012 ;7(12):e53049.

 

VKORC1 (vitamin K epoxide reductase complex subunit 1, 16p11.2) is the main genetic determinant of human response to oral anticoagulants of antivitamin K type (AVK). This gene was recently suggested to be a putative target of positive selection in East Asian populations. In this study, ...

Last Updated: 3 Jan 2013

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Novel Y chromosome breakpoint in an infertile male with a de novo translocation t(Y;16): a case report.
 

Author(s): Yu-Ting Jiang, Hong-Guo Zhang, Rui-Xue Wang, Yang Yu, Zhi-Hong Zhang, Rui-Zhi Liu

Journal: J. Assist. Reprod. Genet.. 2012 Dec;29(12):1427-30.

 

Last Updated: 24 Dec 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chromosome 16" returned 3 free, full-text review articles on human participants. First 3 results:

E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer?
 

Author(s): Anne-Marie Cleton-Jansen

Journal: Breast Cancer Res.. 2002 ;4(1):5-8.

 

Loss of heterozygosity at the long arm of chromosome 16 is one of the most frequent genetic events in breast cancer. In the search for tumour suppressor genes that are the target of loss of heterozygosity at 16q, the E-cadherin gene CDH1 was unveiled by the identification of truncating ...

Last Updated: 6 Mar 2002

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Chromosome 16 inversion in acute myelogenous leukemias with bone marrow eosinophilia.
 

Author(s): R Ueda

Journal: Intern. Med.. 1996 Apr;35(4):241-2.

 

Last Updated: 12 Nov 1996

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Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia.
 

Author(s): P P Liu, A Hajra, C Wijmenga, F S Collins

Journal: Blood. 1995 May;85(9):2289-302.

 

Last Updated: 31 May 1995

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Online Study of Individuals With Genetic Changes and Features of Autism: Simons Variation in Individuals Project (Simons VIP)
 

Status: Recruiting

Condition Summary: 16p11.2 Deletions; 16p11.2 Duplications; 1q21.1 Deletions; 1q21.1 Duplications; ADNP (ADNP1, KIAA0784); ANKRD1 (ANCO1, T13, LZ16); ARID1B (BAF250B); ASXL3 (KIAA1713); BAF105; BAF180 (PBRM1, PB1); BAF190 (SMARCA4/SMARCA2); BAF35 (BCL7B); BAF35b (ACTL6B); BCL11A (CTIP1, EVI9, KIAA1809, FLJ10173); CHD2; CHD8 (KIAA1564, DUPLIN); CTNNB1 (CTNNB); CUL3 (Cullin 3, PHA2E, KIAA0617); DST (BPAG1, BP240); DYRK1A; FOXP1 (QRF1); GRIN2B (NMDAR2B, NR2B); KDM6B (JMJD3, KIAA0346); KMT2E (MLL5); MBD5 (KIAA1461); MED13L (THRAP2, PROSIT240, TRAP240L, KIAA1025); PTEN (PTEN1, MMAC1); REST (NRSF); SCN2A; SMARCC1 (BAF155); SMARCC2 (BAF170); SYNGAP1; Additional Genetic Changes Associated With Autism May be Added as Identified

 

Last Updated: 16 Nov 2015

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Down Syndrome Memantine Follow-up Study
 

Status: Recruiting

Condition Summary: Down Syndrome; Intellectual Disability

 

Last Updated: 25 Nov 2014

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