Chondrosarcoma

Common Name(s)

Chondrosarcoma

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chondrosarcoma" for support, advocacy or research.

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Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chondrosarcoma" for support, advocacy or research.

Logo
Sarcoma Alliance

The Sarcoma Alliance strives to improve the lives of people affected by sarcoma through accurate diagnosis, improved access to care, guidance, education and support.

http://sarcomaalliance.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chondrosarcoma" returned 446 free, full-text research articles on human participants. First 3 results:

MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β-Catenin Signaling Pathway.
 

Author(s): Peng Zhang, Jifeng Li, Yuze Song, Xiao Wang

Journal: Cell. Physiol. Biochem.. 2017 ;42(1):242-253.

 

Recently, microRNAs (miRNA) have been identified as novel regulators in Chondrosarcoma (CHS). This study was aimed to identify the roles of miR-129-5p-5p in regulation of SOX4 and Wnt/β-catenin signaling pathway, as well as cell proliferation and apoptosis in chondrosarcomas.

Last Updated: 23 May 2017

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Celastrol inhibits chondrosarcoma proliferation, migration and invasion through suppression CIP2A/c-MYC signaling pathway.
 

Author(s): Jinhui Wu, Muchen Ding, Ningfang Mao, Yungang Wu, Chao Wang, Jiabin Yuan, Xiong Miao, Jingfeng Li, Zhicai Shi

Journal: J. Pharmacol. Sci.. 2017 May;134(1):22-28.

 

Chondrosarcomas (CS) is the second most frequent tumors of cartilage origin. A small compound extracted from Thunder God Vine (Tripterygium wilfordii Hook. F.) called celastrol can directly bound CIP2A protein and effectively inhibit cell proliferation and induce apoptosis in several ...

Last Updated: 19 May 2017

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The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy.
 

Author(s): Birgit Lohberger, Bibiane Steinecker-Frohnwieser, Nicole Stuendl, Heike Kaltenegger, Andreas Leithner, Beate Rinner

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High grade chondrosarcoma is characterized by its lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing with ...

Last Updated: 15 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chondrosarcoma" returned 54 free, full-text review articles on human participants. First 3 results:

What Is New in the miRNA World Regarding Osteosarcoma and Chondrosarcoma?
 

Author(s): Gaia Palmini, Francesca Marini, Maria Luisa Brandi

Journal:

 

Despite the availability of multimodal and aggressive therapies, currently patients with skeletal sarcomas, including osteosarcoma and chondrosarcoma, often have a poor prognosis. In recent decades, advances in sequencing technology have revealed the presence of RNAs without coding ...

Last Updated: 8 Mar 2017

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Novel therapeutic approaches in chondrosarcoma.
 

Author(s): Genovefa Polychronidou, Vasilios Karavasilis, Seth M Pollack, Paul H Huang, Alex Lee, Robin L Jones

Journal: Future Oncol. 2017 Mar;13(7):637-648.

 

Chondrosarcoma is a malignant tumor of bones, characterized by the production of cartilage matrix. Due to lack of effective treatment for advanced disease, the clinical management of chondrosarcomas is exceptionally challenging. Current research focuses on elucidating the molecular ...

Last Updated: 30 Jan 2017

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Bladder chondrosarcoma plus urothelial carcinoma in recurred transitional cell carcinoma of the upper urinary tract: a case report and literature review.
 

Author(s): Min Hyun Cho, Sung Han Kim, Weon Seo Park, Jae Young Joung, Ho Kyung Seo, Jinsoo Chung, Kang Hyun Lee

Journal:

 

Sarcomatoid urothelial carcinoma (SUC) is a rare malignant neoplasm of the urinary bladder comprising 0.2-0.6 % of all histological bladder tumor subtypes. It presents as a high-stage malignancy and exhibits aggressive biological behavior, regardless of the treatment employed. It ...

Last Updated: 21 Oct 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial
 

Status: Recruiting

Condition Summary: Chondrosarcoma

 

Last Updated: 18 Jul 2017

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Proton Radiation for Chordomas and Chondrosarcomas
 

Status: Recruiting

Condition Summary: Chordomas; Chondrosarcomas

 

Last Updated: 7 Dec 2015

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