Cholesteatoma

Common Name(s)

Cholesteatoma

Cholesteatoma is a type of skin cyst located in the middle ear. It can be congenital (present from birth), but it more commonly occurs as a complication of chronic ear infection. The hallmark symptom is a painless discharge from the ear. Hearing loss, dizziness, and facial muscle paralysis are rare but can result from continued cholesteatoma growth.  Surgery can stop infections and prevent complications.   
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholesteatoma" for support, advocacy or research.

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Vestibular Disorders Association

VEDA's mission is to serve people with vestibular (inner ear balance) disorders by providing access to information, offering a support network, and elevating awareness of the challenges associated with these conditions.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholesteatoma" for support, advocacy or research.

Logo
Vestibular Disorders Association

VEDA's mission is to serve people with vestibular (inner ear balance) disorders by providing access to information, offering a support network, and elevating awareness of the challenges associated with these conditions.

https://vestibular.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholesteatoma" returned 119 free, full-text research articles on human participants. First 3 results:

Fibrous Dysplasia of the Temporal Bone with External Auditory Canal Stenosis and Secondary Cholesteatoma.
 

Author(s): Yu-Hsi Liu, Kuo-Ping Chang

Journal: J Int Adv Otol. 2016 Apr;12(1):125-8.

 

Fibrous dysplasia is a slowly progressive benign fibro-osseous disease, rarely occurring in temporal bones. In these cases, most bony lesions developed from the bony part of the external auditory canals, causing otalgia, hearing impairment, otorrhea, and ear hygiene blockade and probably ...

Last Updated: 25 Jun 2016

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Post-radiotherapy bilateral external auditory canal cholesteatoma.
 

Author(s): Emrah Sapmaz, Battal Tahsin Somuk, Harun Soyalıç, Can Koçak, Erkan Gökçe

Journal: Kulak Burun Bogaz Ihtis Derg. 2016 ;26(1):60-3.

 

In this article, we report a 55-year-old female case was treated with radiotherapy due to nasopharynx carcinoma and diagnosed with bilateral external auditory canal cholesteatoma four years after radiotherapy. Persistent otorrhea was present in the patient and the diagnosis was established ...

Last Updated: 22 Jan 2016

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Identification of altered protein abundances in cholesteatoma matrix via mass spectrometry-based proteomic analysis.
 

Author(s): Derrick R Randall, Phillip S Park, Justin K Chau

Journal:

 

Cholesteatoma are cyst-like structures lined with a matrix of differentiated squamous epithelium overlying connective tissue. Although epithelium normally exhibits self-limited growth, cholesteatoma matrix erodes mucosa and bone suggesting changes in matrix protein constituents that ...

Last Updated: 26 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholesteatoma" returned 19 free, full-text review articles on human participants. First 3 results:

Congenital Intratympanic Cholesteatoma in an Adult Patient: A Case Report and Review of the Literature.
 

Author(s): Barbara Pedruzzi, Marta Mion, Francesco Comacchio

Journal: J Int Adv Otol. 2016 Apr;12(1):119-24.

 

Congenital cholesteatoma within the tympanic membrane is an uncommon entity, with only few cases being documented. The aetiopathogenesis of this lesion is still unknown; however, when cholesteatoma develops in subjects without any history of previous ear inflammation, as in the case ...

Last Updated: 25 Jun 2016

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Consensus-Based Recommendations on the Definition and Classification of Cholesteatoma.
 

Author(s): Ewa Olszewska, Justyna Rutkowska, Nuri Özgirgin

Journal: J Int Adv Otol. 2015 Apr;11(1):81-7.

 

Development of a consensus on the definitions and classification of cholesteatoma is essential for scientific community to exchange information on clinical studies and compare their outcomes. The aim of the study is to reach a consensus among members of the European Academy of Otology ...

Last Updated: 30 Jul 2015

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Updates and knowledge gaps in cholesteatoma research.
 

Author(s): Chin-Lung Kuo, An-Suey Shiao, Matthew Yung, Masafumi Sakagami, Holger Sudhoff, Chih-Hung Wang, Chyong-Hsin Hsu, Chiang-Feng Lien

Journal: Biomed Res Int. 2015 ;2015():854024.

 

The existence of acquired cholesteatoma has been recognized for more than three centuries; however, the nature of the disorder has yet to be determined. Without timely detection and intervention, cholesteatomas can become dangerously large and invade intratemporal structures, resulting ...

Last Updated: 13 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Sep 2016

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