Cholesteatoma

Common Name(s)

Cholesteatoma

Cholesteatoma is a type of skin cyst located in the middle ear. It can be congenital (present from birth), but it more commonly occurs as a complication of chronic ear infection. The hallmark symptom is a painless discharge from the ear. Hearing loss, dizziness, and facial muscle paralysis are rare but can result from continued cholesteatoma growth.  Surgery can stop infections and prevent complications.   
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholesteatoma" for support, advocacy or research.

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Vestibular Disorders Association

VEDA's mission is to serve people with vestibular (inner ear balance) disorders by providing access to information, offering a support network, and elevating awareness of the challenges associated with these conditions.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholesteatoma" for support, advocacy or research.

Logo
Vestibular Disorders Association

VEDA's mission is to serve people with vestibular (inner ear balance) disorders by providing access to information, offering a support network, and elevating awareness of the challenges associated with these conditions.

https://vestibular.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholesteatoma" returned 88 free, full-text research articles on human participants. First 3 results:

Surgical management of middle ear cholesteatoma and reconstruction at the same time.
 

Author(s): Pedro Blanco, Francisco González, Jorge Holguín, Claudia Guerra

Journal:

 

In the surgical management of cholesteatoma, one can opt for a closed technique (simple mastoidectomy) or open surgery (radical mastoidectomy). Open mastoidectomy with reconstruction of the posterior wall and the middle ear in a single surgery combines the advantages of both techniques, ...

Last Updated: 11 Nov 2014

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[One case, two lessons: an aberrant internal carotid artery causing acquired cholesteatoma].
 

Author(s): Sady Selaimen da Costa, Maurício Noschang Lopes da Silva, Letícia Petersen Schmitt Rosito, Fábio André Selaimen

Journal: Braz J Otorhinolaryngol. ;80(5):453-4.

 

Last Updated: 11 Oct 2014

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[Cholesteatoma of the middle ear - retrospective study about 145 cases].
 

Author(s): Brahim Bouaity, Mehdi Chihani, Karim Nadour, Mountassir Moujahid, Mliha Touati, Youssef Darouassi, Haddou Ammar

Journal:

 

Last Updated: 14 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholesteatoma" returned 12 free, full-text review articles on human participants. First 3 results:

Molecular biology of cholesteatoma.
 

Author(s): Alma Maniu, Oana Harabagiu, Maria Perde Schrepler, Andreea Cătană, Bogdan Fănuţă, Carmen Aurelia Mogoantă

Journal: Rom J Morphol Embryol. 2014 ;55(1):7-13.

 

Cholesteatoma is a non-neoplastic, keratinizing lesion, characterized by the proliferation of epithelium with aberrant micro-architecture into the middle ear and mastoid cavity. The exact pathogenic molecular mechanisms behind the formation and propagation of cholesteatoma remain ...

Last Updated: 9 Apr 2014

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Imaging of non-operated cholesteatoma: clinical practice guidelines.
 

Author(s): D Ayache, V Darrouzet, F Dubrulle, C Vincent, S Bobin, M Williams, C Martin,

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Jun;129(3):148-52.

 

Middle ear cholesteatoma is an aggressive form of chronic otitis media requiring surgical therapy. The surgical strategy depends on the location of the lesion, its extensions to the middle ear and mastoid, the anatomical conformation of the tympanomastoid cavities and the health status ...

Last Updated: 5 Jun 2012

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TNF-R2 expression in acquired middle ear cholesteatoma.
 

Author(s): Rodrigo Faller Vitale, Celina Siqueira Barbosa Pereira, Adriana Leal Alves, Jose Humberto Tavares Guerreiro Fregnani, Fernando Quintanilha Ribeiro

Journal: Braz J Otorhinolaryngol. ;77(4):531-6.

 

Acquired middle ear cholesteatoma is a disease which promotes bone erosion resulting in potentially serious complications. The tumor necrosis factor alpha (TNF-α) is present in cholesteatoma and it is related to bone erosion, as shown by different authors. To understand the aggressiveness ...

Last Updated: 23 Aug 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.