Cholera

Common Name(s)

Cholera

Cholera is caused by an infection of the intestine by the bacterium Vibrio cholerae. The illness is often mild or without symptoms, but can sometimes be severe, with symptoms typically appearing in 2-3 days. Severe symptoms are characterized by vomiting, profuse diarrhea, and leg cramps. Rapid loss of body fluids in severe cases can lead to dehydration, shock, and death within hours if left untreated. Cholera can be contracted from drinking or eating contaminated food or water. Cholera can spread quickly in areas that have poor treatment of sewage and drinking water, poor sanitation, and poor hygiene. Medical attention should be found immediately for those who think they may have cholera.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholera" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholera" returned 1227 free, full-text research articles on human participants. First 3 results:

Cholera outbreak following a marriage ceremony in Medinya, Western Ghana.
 

Author(s): Helena Acquah, Keziah Malm, Joyce Der, Gideon Kye-Duodu, Ebenezer Kofi Mensah, Samuel Oko Sackey, Kofi Mensah Nyarko, Edwin Afari

Journal:

 

Cholera is a diarrhoea disease caused by the bacterium e. On 13th June 2011, there was a reported outbreak of acute watery diarrhoea at Medinya among people who eat at a mass traditional wedding ceremony in the Western Region of Ghana. We investigated to characterize the outbreak, ...

Last Updated: 17 Feb 2017

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Notes from the Field: Ongoing Cholera Epidemic - Tanzania, 2015-2016.
 

Author(s): Rupa Narra, Justin M Maeda, Herilinda Temba, Janneth Mghamba, Ali Nyanga, Ashley L Greiner, Muhammad Bakari, Karlyn D Beer, Sae-Rom Chae, Kathryn G Curran, Rachel B Eidex, James J Gibson, Thomas Handzel, Stephen J Kiberiti, Rogath S Kishimba, Haji Lukupulo, Theophil Malibiche, Khalid Massa, Amani E Massay, Lindsey S McCrickard, Geofrey J Mchau, Vida Mmbaga, Ahmed A Mohamed, Elibariki R Mwakapeje, Emmanuel Nestory, Anna E Newton, Elvis Oyugi, Anu Rajasingham, Michelle E Roland, Neema Rusibamayila, Senga Sembuche, Loveness J Urio, Tiffany A Walker, Alice Wang, Robert E Quick

Journal:

 

Last Updated: 16 Feb 2017

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Evolution of the Immune Response against Recombinant Proteins (TcpA, TcpB, and FlaA) as a Candidate Subunit Cholera Vaccine.
 

Author(s): Neda Molaee, Ghasem Mosayebi, Alireza Amozande-Nobaveh, Mohammad Reza Soleyman, Hamid Abtahi

Journal: J Immunol Res. 2017 ;2017():2412747.

 

Vibrio cholerae is the causative agent of cholera and annually leads to death of thousands of people around the globe. Two factors in the pathogenesis of this bacterium are its pili and flagella. The main subunits of pili TcpA, TcpB, and FlaA are the constituent subunit of flagella. ...

Last Updated: 13 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholera" returned 70 free, full-text review articles on human participants. First 3 results:

Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming.
 

Author(s): Fazle Rabbi Chowdhury, Zannatun Nur, Nazia Hassan, Lorenz von Seidlein, Susanna Dunachie

Journal:

 

Vibrio cholerae, a Gram-negative, non-spore forming curved rod is found in diverse aquatic ecosystems around the planet. It is classified according to its major surface antigen into around 206 serogroups, of which O1 and O139 cause epidemic cholera. A recent spatial modelling technique ...

Last Updated: 8 Mar 2017

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Vibrio cholerae Biofilms and Cholera Pathogenesis.
 

Author(s): Anisia J Silva, Jorge A Benitez

Journal:

 

Vibrio cholerae can switch between motile and biofilm lifestyles. The last decades have been marked by a remarkable increase in our knowledge of the structure, regulation, and function of biofilms formed under laboratory conditions. Evidence has grown suggesting that V. cholerae can ...

Last Updated: 5 Feb 2016

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Mechanisms of Cholera Toxin in the Modulation of TH17 Responses.
 

Author(s): Hsing-Chuan Tsai, Reen Wu

Journal: Crit. Rev. Immunol.. 2015 ;35(2):135-52.

 

Numerous studies have shown that TH17 cells and their signature cytokine IL-17A are critical to host defense against various bacterial and fungal infections. The protective responses mediated by TH17 cells and IL-17A include the recruitment of neutrophils, release of antimicrobial ...

Last Updated: 9 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cholera Vaccine Investment Strategy in Bangladesh
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 30 Mar 2016

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Safety and Immunogenicity of Locally Manufactured Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 6 Oct 2016

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Single Dose Oral Cholera Vaccine Study in Dhaka, Bangladesh
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 26 Jul 2015

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