Cholera

Common Name(s)

Cholera

Cholera is caused by an infection of the intestine by the bacterium Vibrio cholerae. The illness is often mild or without symptoms, but can sometimes be severe, with symptoms typically appearing in 2-3 days. Severe symptoms are characterized by vomiting, profuse diarrhea, and leg cramps. Rapid loss of body fluids in severe cases can lead to dehydration, shock, and death within hours if left untreated. Cholera can be contracted from drinking or eating contaminated food or water. Cholera can spread quickly in areas that have poor treatment of sewage and drinking water, poor sanitation, and poor hygiene. Medical attention should be found immediately for those who think they may have cholera.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholera" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholera" returned 1336 free, full-text research articles on human participants. First 3 results:

Molecular characterization of Vibrio cholerae responsible for cholera epidemics in Uganda by PCR, MLVA and WGS.
 

Author(s): Godfrey Bwire, David A Sack, Mathieu Almeida, Shan Li, Joseph B Voeglein, Amanda Kay Debes, Atek Kagirita, Ambrose Wabwire Buyinza, Christopher Garimoi Orach, O Colin Stine

Journal:

 

For almost 50 years sub-Saharan Africa, including Uganda, has experienced several outbreaks due to Vibrio cholerae. Our aim was to determine the genetic relatedness and spread of strains responsible for cholera outbreaks in Uganda.

Last Updated: 31 Dec 1969

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Cholera Epidemic - Lusaka, Zambia, October 2017-May 2018.
 

Author(s): Nyambe Sinyange, Joan M Brunkard, Nathan Kapata, Mazyanga Lucy Mazaba, Kunda G Musonda, Raymond Hamoonga, Muzala Kapina, Fred Kapaya, Lwito Mutale, Ernest Kateule, Francis Nanzaluka, James Zulu, Chileshe Lukwesa Musyani, Alison V Winstead, William W Davis, Hammad S N'cho, Nelia L Mulambya, Patrick Sakubita, Orbie Chewe, Sulani Nyimbili, Ezinne V C Onwuekwe, Nedghie Adrien, Anna J Blackstock, Travis W Brown, Gordana Derado, Nancy Garrett, Sunkyung Kim, Sydney Hubbard, Amy M Kahler, Warren Malambo, Eric Mintz, Jennifer Murphy, Rupa Narra, Gouthami G Rao, Margaret A Riggs, Nicole Weber, Ellen Yard, Khozya D Zyambo, Nathan Bakyaita, Namani Monze, Kennedy Malama, Jabbin Mulwanda, Victor M Mukonka

Journal:

 

On October 6, 2017, an outbreak of cholera was declared in Zambia after laboratory confirmation of Vibrio cholerae O1, biotype El Tor, serotype Ogawa, from stool specimens from two patients with acute watery diarrhea. The two patients had gone to a clinic in Lusaka, the capital city, ...

Last Updated: 31 Dec 1969

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Near real-time forecasting for cholera decision making in Haiti after Hurricane Matthew.
 

Author(s): Damiano Pasetto, Flavio Finger, Anton Camacho, Francesco Grandesso, Sandra Cohuet, Joseph C Lemaitre, Andrew S Azman, Francisco J Luquero, Enrico Bertuzzo, Andrea Rinaldo

Journal:

 

Computational models of cholera transmission can provide objective insights into the course of an ongoing epidemic and aid decision making on allocation of health care resources. However, models are typically designed, calibrated and interpreted post-hoc. Here, we report the efforts ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholera" returned 71 free, full-text review articles on human participants. First 3 results:

Protection against cholera from killed whole-cell oral cholera vaccines: a systematic review and meta-analysis.
 

Author(s): Qifang Bi, Eva Ferreras, Lorenzo Pezzoli, Dominique Legros, Louise C Ivers, Kashmira Date, Firdausi Qadri, Laura Digilio, David A Sack, Mohammad Ali, Justin Lessler, Francisco J Luquero, Andrew S Azman,

Journal: Lancet Infect Dis. 2017 Oct;17(10):1080-1088.

 

Killed whole-cell oral cholera vaccines (kOCVs) are becoming a standard cholera control and prevention tool. However, vaccine efficacy and direct effectiveness estimates have varied, with differences in study design, location, follow-up duration, and vaccine composition posing challenges ...

Last Updated: 31 Dec 1969

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Pandemics, pathogenicity and changing molecular epidemiology of cholera in the era of global warming.
 

Author(s): Fazle Rabbi Chowdhury, Zannatun Nur, Nazia Hassan, Lorenz von Seidlein, Susanna Dunachie

Journal:

 

Vibrio cholerae, a Gram-negative, non-spore forming curved rod is found in diverse aquatic ecosystems around the planet. It is classified according to its major surface antigen into around 206 serogroups, of which O1 and O139 cause epidemic cholera. A recent spatial modelling technique ...

Last Updated: 31 Dec 1969

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Oral Cholera Vaccination Delivery Cost in Low- and Middle-Income Countries: An Analysis Based on Systematic Review.
 

Author(s): Vittal Mogasale, Enusa Ramani, Hyeseung Wee, Jerome H Kim

Journal:

 

Use of the oral cholera vaccine (OCV) is a vital short-term strategy to control cholera in endemic areas with poor water and sanitation infrastructure. Identifying, estimating, and categorizing the delivery costs of OCV campaigns are useful in analyzing cost-effectiveness, understanding ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccine
 

Status: Recruiting

Condition Summary: Cholera; Vibrio Cholerae Infection

 

Last Updated: 14 Dec 2017

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VAXCHORA Pediatric Study
 

Status: Recruiting

Condition Summary: Cholera Vaccination Reaction

 

Last Updated: 3 Jul 2018

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