Cholera

Common Name(s)

Cholera

Cholera is caused by an infection of the intestine by the bacterium Vibrio cholerae. The illness is often mild or without symptoms, but can sometimes be severe, with symptoms typically appearing in 2-3 days. Severe symptoms are characterized by vomiting, profuse diarrhea, and leg cramps. Rapid loss of body fluids in severe cases can lead to dehydration, shock, and death within hours if left untreated. Cholera can be contracted from drinking or eating contaminated food or water. Cholera can spread quickly in areas that have poor treatment of sewage and drinking water, poor sanitation, and poor hygiene. Medical attention should be found immediately for those who think they may have cholera.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cholera" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cholera" returned 1249 free, full-text research articles on human participants. First 3 results:

High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.
 

Author(s): Julie Elisabeth Heggelund, Daniel Burschowsky, Victoria Ariel Bjørnestad, Vesna Hodnik, Gregor Anderluh, Ute Krengel

Journal:

 

Cholera is the prime example of blood-group-dependent diseases, with individuals of blood group O experiencing the most severe symptoms. The cholera toxin is the main suspect to cause this relationship. We report the high-resolution crystal structures (1.1-1.6 Å) of the native cholera ...

Last Updated: 16 Apr 2016

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Chemoproteomic profiling of host and pathogen enzymes active in cholera.
 

Author(s): Stavroula K Hatzios, Sören Abel, Julianne Martell, Troy Hubbard, Jumpei Sasabe, Diana Munera, Lars Clark, Daniel A Bachovchin, Firdausi Qadri, Edward T Ryan, Brigid M Davis, Eranthie Weerapana, Matthew K Waldor

Journal: Nat. Chem. Biol.. 2016 Apr;12(4):268-74.

 

Activity-based protein profiling (ABPP) is a chemoproteomic tool for detecting active enzymes in complex biological systems. We used ABPP to identify secreted bacterial and host serine hydrolases that are active in animals infected with the cholera pathogen Vibrio cholerae. Four V. ...

Last Updated: 19 Mar 2016

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Micro-scale Spatial Clustering of Cholera Risk Factors in Urban Bangladesh.
 

Author(s): Qifang Bi, Andrew S Azman, Syed Moinuddin Satter, Azharul Islam Khan, Dilruba Ahmed, Altaf Ahmed Riaj, Emily S Gurley, Justin Lessler

Journal:

 

Close interpersonal contact likely drives spatial clustering of cases of cholera and diarrhea, but spatial clustering of risk factors may also drive this pattern. Few studies have focused specifically on how exposures for disease cluster at small spatial scales. Improving our understanding ...

Last Updated: 12 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cholera" returned 79 free, full-text review articles on human participants. First 3 results:

Vibrio cholerae Biofilms and Cholera Pathogenesis.
 

Author(s): Anisia J Silva, Jorge A Benitez

Journal:

 

Vibrio cholerae can switch between motile and biofilm lifestyles. The last decades have been marked by a remarkable increase in our knowledge of the structure, regulation, and function of biofilms formed under laboratory conditions. Evidence has grown suggesting that V. cholerae can ...

Last Updated: 5 Feb 2016

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The Impact of Water, Sanitation and Hygiene Interventions to Control Cholera: A Systematic Review.
 

Author(s): Dawn L Taylor, Tanya M Kahawita, Sandy Cairncross, Jeroen H J Ensink

Journal:

 

Cholera remains a significant threat to global public health with an estimated 100,000 deaths per year. Water, sanitation and hygiene (WASH) interventions are frequently employed to control outbreaks though evidence regarding their effectiveness is often missing. This paper presents ...

Last Updated: 19 Aug 2015

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Cholera in Pregnancy: A Systematic Review and Meta-Analysis of Fetal, Neonatal, and Maternal Mortality.
 

Author(s): Nguyen-Toan Tran, Richard Taylor, Annick Antierens, Nelly Staderini

Journal:

 

Maternal infection with cholera may negatively affect pregnancy outcomes. The objective of this research is to systematically review the literature and determine the risk of fetal, neonatal and maternal death associated with cholera during pregnancy.

Last Updated: 16 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Introduction of Cholera Vaccine in Bangladesh
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 26 Jul 2015

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Single Dose Oral Cholera Vaccine Study in Dhaka, Bangladesh
 

Status: Recruiting

Condition Summary: Cholera

 

Last Updated: 26 Jul 2015

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Last Updated: 10 Aug 2016

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