Early onset schizophrenia

Common Name(s)

Early onset schizophrenia, Childhood schizophrenia, Adolescent schizophrenia

Early onset schizophrenia is a rare form of schizophrenia that develops before a child is 17 years old. Schizophrenia is a severe brain disorder that involves problems with thinking, behavior and emotions. Schizophrenia symptoms generally start in the late teens to the mid-30s. Early-onset schizophrenia begins in children younger than age 17. Very early-onset schizophrenia in children younger than age 13 is very rare. Early onset schizophrenia has a significant impact on a child’s behavior and development. Symptoms may build up gradually and may be hard to identify. The earliest signs of schizophrenia in children under 13 may include language delays, late crawling, late walking or abnormal movements. These symptoms may also suggest other conditions including pervasive developmental disorders such as autism spectrum disorders. Symptoms of schizophrenia developing between ages 13-17 may include withdrawal from friends and family, trouble sleeping, depression, lack of motivation and strange behavior. Unfortunately many of these symptoms may also be present during typical teenage development. As children and teens age, later symptoms become more typical of adult schizophrenia and may include hallucinations, delusions, disorganized thinking, and abnormal motor behavior. Teenagers are more likely to experience visual hallucinations and less likely to have delusions than adults.

Schizophrenia is believed to be caused by both genetics and environment. To diagnose schizophrenia, a physician will ask about medical, psychiatric and school performance history and may use imaging tests, such as MRIs, to look for abnormalities of the brain. Schizophrenia requires lifelong treatment by a psychiatrist and therapist. Treatment for childhood schizophrenia may include medications, individual and family therapy, social and academic skills training. Support groups are also a good resource for information and connecting to other families.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Early onset schizophrenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Early onset schizophrenia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Early onset schizophrenia" returned 38 free, full-text research articles on human participants. First 3 results:

Brain network informed subject community detection in early-onset schizophrenia.
 

Author(s): Zhi Yang, Yong Xu, Ting Xu, Colin W Hoy, Daniel A Handwerker, Gang Chen, Georg Northoff, Xi-Nian Zuo, Peter A Bandettini

Journal:

 

Early-onset schizophrenia (EOS) offers a unique opportunity to study pathophysiological mechanisms and development of schizophrenia. Using 26 drug-naïve, first-episode EOS patients and 25 age- and gender-matched control subjects, we examined intrinsic connectivity network (ICN) deficits ...

Last Updated: 3 Jul 2014

Go To URL
White matter abnormalities and cognitive impairment in early-onset schizophrenia-spectrum disorders.
 

Author(s): Katherine A Epstein, Kathryn R Cullen, Bryon A Mueller, Paul Robinson, Susanne Lee, Sanjiv Kumra

Journal: J Am Acad Child Adolesc Psychiatry. 2014 Mar;53(3):362-72.e1-2.

 

To characterize white matter abnormalities in adolescents with early-onset schizophrenia (EOS) relative to 3 comparison groups (adolescents at clinical high risk for developing schizophrenia [CHR], adolescents with cannabis use disorder [CUD], and healthy controls [HC]), and to identify ...

Last Updated: 25 Feb 2014

Go To URL
Childhood onset schizophrenia and early onset schizophrenia spectrum disorders.
 

Author(s): David I Driver, Nitin Gogtay, Judith L Rapoport

Journal: Child Adolesc Psychiatr Clin N Am. 2013 Oct;22(4):539-55.

 

The clinical severity, impact on development, and poor prognosis of childhood onset schizophrenia may represent a more homogeneous group. Positive symptoms in children are necessary for the diagnosis and hallucinations are more often multimodal. In healthy children and children with ...

Last Updated: 9 Sep 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Early onset schizophrenia" returned 2 free, full-text review articles on human participants. First 3 results:

Gray matter alterations in schizophrenia high-risk youth and early-onset schizophrenia: a review of structural MRI findings.
 

Author(s): Benjamin K Brent, Heidi W Thermenos, Matcheri S Keshavan, Larry J Seidman

Journal: Child Adolesc Psychiatr Clin N Am. 2013 Oct;22(4):689-714.

 

This article reviews the literature on structural magnetic resonance imaging findings in pediatric and young adult populations at clinical or genetic high-risk for schizophrenia and early-onset schizophrenia. The implications of this research are discussed for understanding the pathophysiology ...

Last Updated: 9 Sep 2013

Go To URL
A systematic review of the long-term outcome of early onset schizophrenia.
 

Author(s): Lars Clemmensen, Ditte Lammers Vernal, Hans-Christoph Steinhausen

Journal:

 

The current review analyzes the long-term outcome and prognosis of early onset schizophrenia based on previously published studies in 1980.

Last Updated: 14 Dec 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

5-HTR2A, DRD2,and COMT Genes Polymorphisms and Olanzapine Plasma Concentration in Treatment of Early-onset Schizophrenia
 

Status: Not yet recruiting

Condition Summary: Early-onset Schizophrenia

 

Last Updated: 5 May 2015

Go to URL
3D High Resolution Anorectal Manometry in Children After Surgery for Anorectal Disorders
 

Status: Recruiting

Condition Summary: Children; Anorectal Disorder; Anorectal Atresia; Hirschsprung Disease

 

Last Updated: 1 Jul 2015

Go to URL
Development and Pilot Evaluation of Modified Cognitive Behavioural Therapy for Adolescents With Early Onset Psychosis
 

Status: Recruiting

Condition Summary: Psychotic Disorders; Schizophrenia; Schizoaffective Disorder; Delusional Disorder; Schizophreniform Disorder

 

Last Updated: 19 Feb 2009

Go to URL