Chikungunya

Common Name(s)

Chikungunya

Chikungunya is a viral disease spread to people through the bites of infected female mosquitoes. The onset of this disease usually presents itself between four and eight days after being bitten by an infected mosquito. The first sign of infection is a fever, typically with debilitating joint pain. Other symptoms include muscle pain, headache, nausea, fatigue, and rash. Generally most people make a complete recovery, but in some cases, there may be persistent joint pain that can last for several months or even years. Additional complications may occur, including eye, neurological, and heart complications. Those with only mild symptoms may go undiagnosed, or may be misdiagnosed, especially in areas where dengue fever or other mosquito borne illnesses occur, as the same mosquito species transmit these diseases. Currently, there is no cure for the disease, and the main focus in on treatment and alleviation of symptoms. Chikungunya has been identified in about 40 countries, primarily in sub-Saharan Africa, South Asia, and Southeast Asia.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chikungunya" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chikungunya" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chikungunya" returned 494 free, full-text research articles on human participants. First 3 results:

Long-Lasting Immune Protection and Other Epidemiological Findings after Chikungunya Emergence in a Cambodian Rural Community, April 2012.
 

Author(s): Beatriz Galatas, Sowath Ly, Veasna Duong, Kathy Baisley, Kunthy Nguon, Siam Chan, Rekol Huy, Sovann Ly, Sopheak Sorn, Leakhann Som, Philippe Buchy, Arnaud Tarantola

Journal:

 

The East/Central/South African genotype of Chikungunya virus with the E1-A226V mutation emerged in 2011 in Cambodia and spread in 2012. An outbreak of 190 cases was documented in Trapeang Roka, a rural village. We surveyed 425 village residents within 3-4 weeks after the outbreak, ...

Last Updated: 12 Jan 2016

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Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases.
 

Author(s): Nikita Sahadeo, Hamish Mohammed, Orchid M Allicock, Albert J Auguste, Steven G Widen, Kimberly Badal, Krishna Pulchan, Jerome E Foster, Scott C Weaver, Christine V F Carrington

Journal:

 

Local transmission of Chikungunya virus (CHIKV) was first documented in Trinidad and Tobago (T&T) in July 2014 preceding a large epidemic. At initial presentation, it is difficult to distinguish chikungunya fever (CHIKF) from other acute undifferentiated febrile illnesses (AUFIs), ...

Last Updated: 20 Nov 2015

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Structural Studies of Chikungunya Virus-Like Particles Complexed with Human Antibodies: Neutralization and Cell-to-Cell Transmission.
 

Author(s): Jason Porta, Vidya Mangala Prasad, Cheng-I Wang, Wataru Akahata, Lisa F P Ng, Michael G Rossmann

Journal:

 

Chikungunya virus is a positive-stranded RNA alphavirus. Structures of chikungunya virus-like particles in complex with strongly neutralizing antibody Fab fragments (8B10 and 5F10) were determined using cryo-electron microscopy and X-ray crystallography. By fitting the crystallographically ...

Last Updated: 16 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chikungunya" returned 31 free, full-text review articles on human participants. First 3 results:

A Re-Examination of the History of Etiologic Confusion between Dengue and Chikungunya.
 

Author(s): Goro Kuno

Journal:

 

Contrary to the perception of many researchers that the recent invasion of chikungunya (CHIK) in the Western Hemisphere marked the first episode in history, a recent publication reminded them that CHIK had prevailed in the West Indies and southern regions of the United States from ...

Last Updated: 13 Nov 2015

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Chikungunya disease: gaps and opportunities in public health and research in the Americas.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Oct;90(42):571-6.

 

Last Updated: 16 Oct 2015

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Symptoms, Diagnosis, and Treatment

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There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Pilot Study of Chikungunya Virus Infections in Southern Taiwan
 

Status: Recruiting

Condition Summary: Chikungunya Fever

 

Last Updated: 31 Mar 2015

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RT-PCR on Urine Samples: Added Value for the Diagnosis of Chikungunya Virus Infection
 

Status: Recruiting

Condition Summary: Chikungunya Fever

 

Last Updated: 16 Mar 2016

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Trial for Safety and Immunogenicity of a Chikungunya Vaccine, VRC-CHKVLP059-00-VP, in Healthy Adults
 

Status: Recruiting

Condition Summary: Chikungunya Virus Infection

 

Last Updated: 16 Dec 2015

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