Chikungunya

Common Name(s)

Chikungunya

Chikungunya is a viral disease spread to people through the bites of infected female mosquitoes. The onset of this disease usually presents itself between four and eight days after being bitten by an infected mosquito. The first sign of infection is a fever, typically with debilitating joint pain. Other symptoms include muscle pain, headache, nausea, fatigue, and rash. Generally most people make a complete recovery, but in some cases, there may be persistent joint pain that can last for several months or even years. Additional complications may occur, including eye, neurological, and heart complications. Those with only mild symptoms may go undiagnosed, or may be misdiagnosed, especially in areas where dengue fever or other mosquito borne illnesses occur, as the same mosquito species transmit these diseases. Currently, there is no cure for the disease, and the main focus in on treatment and alleviation of symptoms. Chikungunya has been identified in about 40 countries, primarily in sub-Saharan Africa, South Asia, and Southeast Asia.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chikungunya" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chikungunya" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chikungunya" returned 615 free, full-text research articles on human participants. First 3 results:

Chikungunya and Zika Virus Cases Detected against a Backdrop of Endemic Dengue Transmission in Vietnam.
 

Author(s): Nguyen Than Ha Quyen, Duong Thi Hue Kien, Maia Rabaa, Nguyen Minh Tuan, Tran Thuy Vi, Le Van Tan, Nguyen Thanh Hung, Ha Manh Tuan, Ta Van Tram, Nguyen Le Da Ha, Han Khoi Quang, Nguyen Quoc Doanh, Nguyen Van Vinh Chau, Bridget Wills, Cameron P Simmons

Journal: Am. J. Trop. Med. Hyg.. 2017 Jul;97(1):146-150.

 

Between 2010 and 2014, four chikungunya and two Zika virus infections were identified among 8,105 febrile children in southern Vietnam. Zika viruses were linked to French Polynesian strains, chikungunya to Cambodian strains. Against a backdrop of endemic dengue transmission, chikungunya ...

Last Updated: 18 Jul 2017

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Encephalitis associated with inappropriate antidiuretic hormone secretion due to chikungunya infection in Recife, State of Pernambuco, Brazil.
 

Author(s): Norma Lucena-Silva, Maria Elisa Lucena Sales de Melo Assunção, Frederico Antônio Pereira Ramos, Fernanda Azevedo, Ronaldo Lessa, Marli Tenório Cordeiro, Carlos Alexandre Antunes de Brito

Journal: Rev. Soc. Bras. Med. Trop.. ;50(3):417-422.

 

The symptoms of chikungunya virus (CHIKV) infection include fever, headache, muscle aches, skin rash, and polyarthralgia, characterized by intense pain, edema, and temporary functional impairment. This is the first report of encephalitis caused by CHIKV infection associated with an ...

Last Updated: 12 Jul 2017

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Encephalitis associated with the chikungunya epidemic outbreak in Brazil: report of 2 cases with neuroimaging findings.
 

Author(s): Licia Pacheco Pereira, Rafaela Villas-Bôas, Stephanie Suzanne de Oliveira Scott, Paulo Ribeiro Nóbrega, Manoel Alves Sobreira-Neto, José Daniel Vieira de Castro, Bruno Cavalcante, Pedro Braga-Neto

Journal: Rev. Soc. Bras. Med. Trop.. ;50(3):413-416.

 

Chikungunya, an alphavirus infection presenting with fever, rash, and polyarthritis, is most often an acute febrile illness. Neurologic complications of chikungunya infection have been reported. Here we report the clinical and neuroimaging data of 2 patients with chikungunya-associated ...

Last Updated: 12 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chikungunya" returned 48 free, full-text review articles on human participants. First 3 results:

Urban Chikungunya in the Middle East and North Africa: A systematic review.
 

Author(s): John M Humphrey, Natalie B Cleton, Chantal B E M Reusken, Marshall J Glesby, Marion P G Koopmans, Laith J Abu-Raddad

Journal:

 

The epidemiology of Chikungunya virus (CHIKV) in the Middle East and North Africa (MENA) is not well characterized despite increasing recognition of its expanding infection and disease burden in recent years.

Last Updated: 26 Jun 2017

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Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies.
 

Author(s): Laurie A Silva, Terence S Dermody

Journal: J. Clin. Invest.. 2017 Mar;127(3):737-749.

 

Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and headache. CHIKV is transmitted by Aedes species of mosquitoes and is capable of an epidemic, urban transmission ...

Last Updated: 1 Mar 2017

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Dengue infection in the nervous system: lessons learned for Zika and Chikungunya.
 

Author(s): Marzia Puccioni-Sohler, Natalia Roveroni, Carolina Rosadas, Fernando Ferry, Jose Mauro Peralta, Amilcar Tanuri

Journal: Arq Neuropsiquiatr. 2017 Feb;75(2):123-126.

 

Dengue, Zika and Chikungunya are emerging arboviruses and important causes of acute febrile disease in tropical areas. Although dengue does not represent a new condition, a geographic expansion over time has occurred with the appearance of severe neurological complications. Neglect ...

Last Updated: 22 Feb 2017

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of a Live Attenuated Chikungunya Vaccine in a Previously Epidemic Area
 

Status: Recruiting

Condition Summary: Chikungunya

 

Last Updated: 17 Aug 2017

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Phase II Study to Evaluate Safety and Immunogenicity of a Chikungunya Vaccine
 

Status: Recruiting

Condition Summary: Chikungunya Virus Infection

 

Last Updated: 21 Dec 2016

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The Pilot Study of Chikungunya Virus Infections in Southern Taiwan
 

Status: Recruiting

Condition Summary: Chikungunya Fever

 

Last Updated: 7 May 2017

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