Acquired Hemophilia

Common Name(s)

Acquired Hemophilia

Acquired hemophilia is a rare form of hemophilia in which the body makes specialized proteins called autoantibodies that attack and disable coagulation factors (proteins in the blood that assist with the clotting process).  The most common coagulation factor attacked is coagulation factor VIII, though other coagulation factors, including factor V and factor IX have been associated with the condition. The production of autoantibodies is sometimes associated with pregnancy, immune system disorders (e.g., systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome), viral infections cancer, or allergic reactions to certain drugs. In about half of cases, the cause of acquired hemophilia is unknown. Treatment may vary from person to person.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acquired Hemophilia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acquired Hemophilia" returned 46 free, full-text research articles on human participants. First 3 results:

[Acquired hemophilia presenting as gross hematuria and perineal subcutaneous hemorrhage after prostate biopsy: a case report].
 

Author(s): Hiroko Kimura, Masayuki Uegaki, Teruyoshi Aoyama, Takashi Miyoshi, Kenichi Nagai, Takayuki Hashimura

Journal: Hinyokika Kiyo. 2013 May;59(5):305-8.

 

Acquired hemophilia is a rare disease that can result in life threatening bleeding associated with coagulation factor VIII inhibitors. A 61-year-old man presented gross hematuria and urinary retention. A retrograde pyelography, cystoscopy, abdominal computed tomography and prostate ...

Last Updated: 30 May 2013

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Acquired hemophilia A associated with IgG4-related lung disease in a patient with autoimmune pancreatitis.
 

Author(s): Keishi Sugino, Kyoko Gocho, Fumiaki Ishida, Naoshi Kikuchi, Nao Hirota, Keita Sato, Go Sano, Kazutoshi Isobe, Susumu Sakamoto, Yujiro Takai, Yoshinobu Hata, Kazutoshi Shibuya, Toshimasa Uekusa, Atsuko Kurosaki, Sakae Homma

Journal: Intern. Med.. 2012 ;51(22):3151-4.

 

Immunoglobulin G4 (IgG4)-related lung diseases can occur in patients with autoimmune pancreatitis (AIP). However, the causal relationship between AIP and acquired hemophilia A (AH) is unknown. We herein report the first case of AH associated with IgG4-related lung disease that developed ...

Last Updated: 16 Nov 2012

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[A case of myasthenia gravis combined with acquired hemophilia A].
 

Author(s): Jin-chun Jing, Zhe Piao, Fu-shun Wu

Journal: Zhonghua Xue Ye Xue Za Zhi. 2012 Jun;33(6):443.

 

Last Updated: 12 Sep 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acquired Hemophilia" returned 2 free, full-text review articles on human participants. First 3 results:

Acquired hemophilia associated with autoimmune bullous diseases: a report of two cases and a review of the literature.
 

Author(s): Shinichi Makita, Takumi Aoki, Akira Watarai, Azusa Aida, Takuji Katayama, Mikio Danbara, Masaaki Higashihara, Koji Miyazaki

Journal: Intern. Med.. 2013 ;52(7):807-10.

 

Acquired hemophilia (AHA) is a relatively rare and life-threatening disease caused by autoantibodies against factor VIII. Autoimmune bullous diseases (ABD) are also caused by autoantibodies against specific skin proteins. We herein report two cases of AHA associated with ABD. These ...

Last Updated: 2 Apr 2013

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Acquired hemophilia.
 

Author(s): P Bouvry, P Recloux

Journal: Haematologica. ;79(6):550-6.

 

Acquired hemophilia is a very rare disease characterized by the presence of an autoantibody (mainly IgG) to factor VIII, with a clinical presentation resembling hemophilia A. It is associated with various autoimmune or dermatologic diseases, pregnancy, cancer, or drug ingestion, but ...

Last Updated: 25 Apr 1995

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Turkish Acquired Haemophilia Registry
 

Status: Not yet recruiting

Condition Summary: Acquired Haemophilia

 

Last Updated: 26 Jul 2011

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Last Updated: 18 Jun 2014

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Use of a TGA and TEM in the Assessment of the Efficacy of Treatment With APCC or rFVIIa
 

Status: Recruiting

Condition Summary: Haemophilia

 

Last Updated: 24 Jun 2014

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