Acquired Hemophilia

Common Name(s)

Acquired Hemophilia

Acquired hemophilia is a rare form of hemophilia in which the body makes specialized proteins called autoantibodies that attack and disable coagulation factors (proteins in the blood that assist with the clotting process).  The most common coagulation factor attacked is coagulation factor VIII, though other coagulation factors, including factor V and factor IX have been associated with the condition. The production of autoantibodies is sometimes associated with pregnancy, immune system disorders (e.g., systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome), viral infections cancer, or allergic reactions to certain drugs. In about half of cases, the cause of acquired hemophilia is unknown. Treatment may vary from person to person.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acquired Hemophilia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Acquired Hemophilia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Acquired Hemophilia" returned 83 free, full-text research articles on human participants. First 3 results:

Hemorrhagic pericardial effusion as the debut of acquired hemophilia in a chronic lymphocytic leukemia patient: A case report, and a review of acquired hemophilia A-related hematological malignancies.
 

Author(s): José María Bastida, María Teresa Cano-Mozo, Felix Lopez-Cadenas, Victor Eduardo Vallejo, Soraya Merchán, Cecilia Santos-Montón, David González-Calle, Javier Carrillo, Ana Africa Martín, Jose Angel Torres-Hernández, Marcos González, Francisco Martín-Herrero, Pedro Pabón, Jose Ramon González-Porras

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8669.

 

Acquired hemophilia A (AHA) is a rare bleeding disease caused by autoantibodies against factor VIII. Spontaneous bleeding symptoms usually affect the skin and muscle, while pericardial effusion is an extremely rare manifestation. In the elderly, anticoagulant treatment is frequent ...

Last Updated: 31 Dec 1969

Go To URL
Acquired Hemophilia A in an advanced age patient of hispanic origin: a case report.
 

Author(s): Nalyssa I Rivera Cora, Freddie Irizarry Delgado, Santa M Merle Ramírez, Jorge Vera Quiñones

Journal:

 

Acquired Hemophilia A (AHA) is a rare hematological disorder that exhibits an incidence of approximately 1.5 cases per million patients a year. It is characterized by the development of autoantibodies against circulating Factor VIII coagulation proteins which, in turn, which in turn ...

Last Updated: 31 Dec 1969

Go To URL
Acquired Hemophilia A in a Patient with Non-Small Cell Lung Carcinoma: A Rare Paraneoplastic Phenomenon.
 

Author(s): Gal Ben Haim, Uri Manor, Sarit Appel, Shadan Lalezari, Reuma Margalit-Yehuda, Shmuel Steinlauf

Journal: Isr. Med. Assoc. J.. 2017 Feb;19(2):128-130.

 

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Acquired Hemophilia" returned 5 free, full-text review articles on human participants. First 3 results:

Acquired hemophilia A: an underdiagnosed, severe bleeding disorder.
 

Author(s): Joanna Zdziarska, Jacek Musiał

Journal: Pol. Arch. Med. Wewn.. 2014 ;124(4):200-6.

 

Acquired hemophilia is a rare bleeding disorder caused by autoantibodies that inhibit coagulation factor VIII. In most cases, it manifests with severe, often life‑threatening bleeds. Acquired hemophilia may be idiopathic or secondary to another condition, most commonly other autoimmune ...

Last Updated: 31 Dec 1969

Go To URL
Acquired hemophilia associated with autoimmune bullous diseases: a report of two cases and a review of the literature.
 

Author(s): Shinichi Makita, Takumi Aoki, Akira Watarai, Azusa Aida, Takuji Katayama, Mikio Danbara, Masaaki Higashihara, Koji Miyazaki

Journal: Intern. Med.. 2013 ;52(7):807-10.

 

Acquired hemophilia (AHA) is a relatively rare and life-threatening disease caused by autoantibodies against factor VIII. Autoimmune bullous diseases (ABD) are also caused by autoantibodies against specific skin proteins. We herein report two cases of AHA associated with ABD. These ...

Last Updated: 31 Dec 1969

Go To URL
Treatment of acquired hemophilia A.
 

Author(s): P W Collins

Journal: J. Thromb. Haemost.. 2007 May;5(5):893-900.

 

Acquired hemophilia A (AH) is an autoimmune disease that leads to potentially severe bleeding. Management relies on rapid and accurate diagnosis, control of bleeding episodes and eradication of the inhibitor by immunosuppression. There is extensive literature about the disease but ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 24 Feb 2018

Go to URL

Last Updated: 18 Nov 2016

Go to URL