Heart Disease

Common Name(s)

Heart Disease

Heart disease, also known as cardiovascular disease, is a term that describes a range of conditions that affect the heart. Diseases that affect the heart’s muscle (cardiomyopathy), rhythm (arrhythmia), structure (congenital heart defect), or blood vessels (coronary artery disease) are all forms of heart disease. Symptoms of heart disease depend on the specific condition. A weak heart muscle may cause fatigue, dizziness, and swelling of the legs, ankles and feet. Symptoms of an abnormal heart rhythm may include chest pain, dizziness, shortness of breath, or a racing or slow heartbeat. Individuals who were born with an abnormality in the structure of the heart may experience swelling in the legs or abdomen, pale or blue skin color, or shortness of breath. Chest pain, shortness of breath, and pain in the legs, arms, neck, jaw, or throat may be a result of heart disease in the blood vessels.

There are many causes of heart disease, depending on the specific form. There are also a few factors that can increase the risk for heart problems. These factors include older age, poor diet, high blood pressure, smoking, a family history of heart disease, stress, obesity, diabetes, high cholesterol levels, and poor hygiene. Doctors use a combination of tests and exams to diagnose heart disease. These tests may include a medical history, a family history, a physical exam, blood tests, an assessment of heart rhythm using electrical signals (electrocardiogram or ECG), and an ultrasound image of your heart (echocardiogram). Lifestyle changes, such as exercising more, eating a healthy diet, or quitting smoking may decrease the risk for heart disease. Some forms of heart disease require treatment with medication, surgery or other medical procedures. Emergency medical attention is recommended for symptoms of chest pain, fatigue or fainting in association with heart disease. Talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

Last Updated: 11 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

http://www.mendedhearts.org

Last Updated: 11 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heart Disease" returned 7608 free, full-text research articles on human participants. First 3 results:

Acute rheumatic fever and rheumatic heart disease among children--American Samoa, 2011-2012.
 

Author(s): Amanda Beaudoin, Laura Edison, Camille E Introcaso, Lucy Goh, James Marrone, Amelita Mejia, Chris Van Beneden,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 May;64(20):555-8.

 

Acute rheumatic fever is a nonsuppurative, immune-mediated consequence of group A streptococcal pharyngitis (strep throat). Recurrent or severe acute rheumatic fever can cause permanent cardiac valve damage and rheumatic heart disease, which increases the risk for cardiac conditions ...

Last Updated: 29 May 2015

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Systolic and diastolic dysfunction of the right heart ventricle in patients with chronic obstructive pulmonary disease in extremely cold climate.
 

Author(s): Anna Innokentievna Sivtseva, Andrew Vladislavovich Strutynsky, Vadim Grigorievich Krivoshapkin, Elena Nikolaevna Sivtseva, Marianna Adolfovna Ivanova, Leonid Fedorovich Timofeev

Journal:

 

The paper describes echocardiographic values of systolic and diastolic dysfunction the right heart ventricle in 229 patients with chronic obstructive pulmonary disease. In our patients the values AvPAP (?25 mmHg while resting), FDDrv and FSDrv (>26 and 20 mm respectively), the thickness ...

Last Updated: 7 May 2015

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c.620C>T mutation in GATA4 is associated with congenital heart disease in South India.
 

Author(s): Saidulu Mattapally, Sheikh Nizamuddin, Kona Samba Murthy, Kumarasamy Thangaraj, Sanjay K Banerjee

Journal:

 

Congenital heart diseases (CHDs) usually refer to abnormalities in the structure and/or function of the heart that arise before birth. GATA4 plays an important role in embryonic heart development, hence the aim of this study was to find the association of GATA4 mutations with CHD ...

Last Updated: 1 May 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heart Disease" returned 1119 free, full-text review articles on human participants. First 3 results:

2014 ACC/AHA/AATS/PCNA/SCAI/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons.
 

Author(s): Stephan D Fihn, James C Blankenship, Karen P Alexander, John A Bittl, John G Byrne, Barbara J Fletcher, Gregg C Fonarow, Richard A Lange, Glenn N Levine, Thomas M Maddox, Srihari S Naidu, E Magnus Ohman, Peter K Smith, Jeffrey L Anderson, Jonathan L Halperin, Nancy M Albert, Biykem Bozkurt, Ralph G Brindis, Lesley H Curtis, David DeMets, Robert A Guyton, Judith S Hochman, Richard J Kovacs, E Magnus Ohman, Susan J Pressler, Frank W Sellke, Win-Kuang Shen, , , , ,

Journal: J. Thorac. Cardiovasc. Surg.. 2015 Mar;149(3):e5-23.

 

Last Updated: 1 Apr 2015

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Pulmonary arterial hypertension associated with bronchopulmonary dysplasia and congenital heart disease in preterm infants. A case report of a preterm infant with recurrent pulmonary hypertension after corrective cardiac surgery and review of the literature.
 

Author(s): Jun Muneuchi, Ayako Kuraoka, Mamie Watanabe, Yoshie Ochiai, Kunitaka Joo

Journal: Int Heart J. 2015 ;56 Suppl():S22-5.

 

In preterm infants with congenital heart disease, concomitant bronchopulmonary dysplasia (BPD) is associated with relatively poor clinical outcomes because of the increased pulmonary vascular resistance and adverse effects of inflammation on the damaged lungs, even after surgery. ...

Last Updated: 19 Mar 2015

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Can pulmonary vasodilator therapy expand the operative indications for congenital heart disease?
 

Author(s): Kei Inai

Journal: Int Heart J. 2015 ;56 Suppl():S12-6.

 

The operability of congenital heart disease with left to right shunt depends on the severity of the pulmonary vascular disease induced by the increased pulmonary blood flow. Although some recommendations exist regarding operative indications according to pathological, hemodynamic, ...

Last Updated: 19 Mar 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Genetic Basis of Acquired Heart Disease in Africa
 

Status: Recruiting

Condition Summary: Rheumatic Heart Disease; Rheumatic Fever; Endomyocardial Fibrosis; Acquired Heart Disease

 

Last Updated: 14 Feb 2015

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The Genetic Basis of Congenital Heart Disease in Africa
 

Status: Recruiting

Condition Summary: Congenital Heart Disease; Heart Disease

 

Last Updated: 27 Jun 2015

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Active With Heart Disease
 

Status: Not yet recruiting

Condition Summary: Heart Disease

 

Last Updated: 20 Jun 2012

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