Heart Disease

Common Name(s)

Heart Disease

Heart disease, also known as cardiovascular disease, is a term that describes a range of conditions that affect the heart. Diseases that affect the heart’s muscle (cardiomyopathy), rhythm (arrhythmia), structure (congenital heart defect), or blood vessels (coronary artery disease) are all forms of heart disease. Symptoms of heart disease depend on the specific condition. A weak heart muscle may cause fatigue, dizziness, and swelling of the legs, ankles and feet. Symptoms of an abnormal heart rhythm may include chest pain, dizziness, shortness of breath, or a racing or slow heartbeat. Individuals who were born with an abnormality in the structure of the heart may experience swelling in the legs or abdomen, pale or blue skin color, or shortness of breath. Chest pain, shortness of breath, and pain in the legs, arms, neck, jaw, or throat may be a result of heart disease in the blood vessels.

There are many causes of heart disease, depending on the specific form. There are also a few factors that can increase the risk for heart problems. These factors include older age, poor diet, high blood pressure, smoking, a family history of heart disease, stress, obesity, diabetes, high cholesterol levels, and poor hygiene. Doctors use a combination of tests and exams to diagnose heart disease. These tests may include a medical history, a family history, a physical exam, blood tests, an assessment of heart rhythm using electrical signals (electrocardiogram or ECG), and an ultrasound image of your heart (echocardiogram). Lifestyle changes, such as exercising more, eating a healthy diet, or quitting smoking may decrease the risk for heart disease. Some forms of heart disease require treatment with medication, surgery or other medical procedures. Emergency medical attention is recommended for symptoms of chest pain, fatigue or fainting in association with heart disease. Talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

Last Updated: 11 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

http://www.mendedhearts.org

Last Updated: 11 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heart Disease" returned 9274 free, full-text research articles on human participants. First 3 results:

Gender differences in the prevalence of congenital heart disease in Down's syndrome: a brief meta-analysis.
 

Author(s): Tereza Cristina Pinheiro Diogenes, Felipe Alves Mourato, José Luiz de Lima Filho, Sandra da Silva Mattos

Journal:

 

Down's syndrome (DS) affects one per 700 live births and congenital heart disease (CHD) occurs in 40-60% of these patients. Contributing factors to the association between DS and CHD are being unraveled. Gender could be one of them.

Last Updated: 7 Oct 2017

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Carotid atherosclerosis and its relationship to coronary heart disease and stroke risk in patients with type 2 diabetes mellitus.
 

Author(s): Yan Wu, Jie He, Xue Sun, Yi-Ming Zhao, Han-Yu Lou, Xiao-Li Ji, Xiao-Hong Pang, Li-Zhen Shan, Ying-Xiu Kang, Jun Xu, Song-Zhao Zhang, Yong-Jian Wang, Yue-Zhong Ren, Peng-Fei Shan

Journal: Medicine (Baltimore). 2017 Sep;96(39):e8151.

 

Carotid atherosclerosis (CA) and carotid plaque (CP) are highly correlated with cardiovascular disease. We aimed to determine the prevalence of CA and CP and their relationship with 10-year risks of stroke and coronary heart disease (CHD) in type 2 diabetes mellitus (T2DM).We studied ...

Last Updated: 27 Sep 2017

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Cognitive function in patients with stable coronary heart disease: Related cerebrovascular and cardiovascular responses.
 

Author(s): Mathieu Gayda, Vincent Gremeaux, Louis Bherer, Martin Juneau, Joffrey Drigny, Olivier Dupuy, Gabriel Lapierre, Véronique Labelle, Annik Fortier, Anil Nigam

Journal:

 

Chronic exercise has been shown to prevent or slow age-related decline in cognitive functions in otherwise healthy, asymptomatic individuals. We sought to assess cognitive function in a stable coronary heart disease (CHD) sample and its relationship to cerebral oxygenation-perfusion, ...

Last Updated: 22 Sep 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heart Disease" returned 1361 free, full-text review articles on human participants. First 3 results:

Genetic polymorphism of methylenetetrahydrofolate reductase as a potential risk factor for congenital heart disease: A meta-analysis in Chinese pediatric population.
 

Author(s): Ye Yuan, Xia Yu, Fenglan Niu, Na Lu

Journal: Medicine (Baltimore). 2017 Jun;96(23):e7057.

 

A meta-analysis of polymorphism C677T (rs1801133) of the methylene tetrahydrofolate reductase (MTHFR) gene as a potential risk factor for congenital heart disease (CHD) in Chinese paediatric population was studied in view of the previously reported controversial results.

Last Updated: 7 Jun 2017

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Associations of GATA4 genetic mutations with the risk of congenital heart disease: A meta-analysis.
 

Author(s): Yanwei Zhang, Feng Ai, Jiayong Zheng, Bangtian Peng

Journal: Medicine (Baltimore). 2017 May;96(18):e6857.

 

GATA4 gene is a cardiac transcriptional factor playing important role in cardiac formation and development. Three GATA4 gene mutations, 99 G>T, 487 C>T, and 354 A>C, have been reported in congenital heart disease (CHD). Therefore, a meta-analysis was performed to explore the associations ...

Last Updated: 4 May 2017

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Role of the fatty acid-binding protein 4 in heart failure and cardiovascular disease.
 

Author(s): Ricardo Rodríguez-Calvo, Josefa Girona, Josep M Alegret, Alba Bosquet, Daiana Ibarretxe, Lluís Masana

Journal: J. Endocrinol.. 2017 Jun;233(3):R173-R184.

 

Obesity and ectopic fat accumulation in non-adipose tissues are major contributors to heart failure (HF) and cardiovascular disease (CVD). Adipocytes act as endocrine organs by releasing a large number of bioactive molecules into the bloodstream, which participate in a communication ...

Last Updated: 19 Apr 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Rheumatic Heart Disease School Project
 

Status: Recruiting

Condition Summary: Rheumatic Heart Disease

 

Last Updated: 20 Sep 2017

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Last Updated: 24 Jan 2017

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Exercise Training in Grown-up Congenital Heart Disease
 

Status: Recruiting

Condition Summary: Congenital Heart Disease

 

Last Updated: 6 Jul 2016

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