Heart Disease

Common Name(s)

Heart Disease

Heart disease, also known as cardiovascular disease, is a term that describes a range of conditions that affect the heart. Diseases that affect the heart’s muscle (cardiomyopathy), rhythm (arrhythmia), structure (congenital heart defect), or blood vessels (coronary artery disease) are all forms of heart disease. Symptoms of heart disease depend on the specific condition. A weak heart muscle may cause fatigue, dizziness, and swelling of the legs, ankles and feet. Symptoms of an abnormal heart rhythm may include chest pain, dizziness, shortness of breath, or a racing or slow heartbeat. Individuals who were born with an abnormality in the structure of the heart may experience swelling in the legs or abdomen, pale or blue skin color, or shortness of breath. Chest pain, shortness of breath, and pain in the legs, arms, neck, jaw, or throat may be a result of heart disease in the blood vessels.

There are many causes of heart disease, depending on the specific form. There are also a few factors that can increase the risk for heart problems. These factors include older age, poor diet, high blood pressure, smoking, a family history of heart disease, stress, obesity, diabetes, high cholesterol levels, and poor hygiene. Doctors use a combination of tests and exams to diagnose heart disease. These tests may include a medical history, a family history, a physical exam, blood tests, an assessment of heart rhythm using electrical signals (electrocardiogram or ECG), and an ultrasound image of your heart (echocardiogram). Lifestyle changes, such as exercising more, eating a healthy diet, or quitting smoking may decrease the risk for heart disease. Some forms of heart disease require treatment with medication, surgery or other medical procedures. Emergency medical attention is recommended for symptoms of chest pain, fatigue or fainting in association with heart disease. Talk with your doctor to decide which treatment option is best for you.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

Last Updated: 11 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Disease" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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Mended Hearts, Inc.

Our mission is dedicated to “Inspiring hope and improving the quality of life for heart patients and their families through ongoing peer-to-peer support”.

http://www.mendedhearts.org

Last Updated: 11 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heart Disease" returned 8789 free, full-text research articles on human participants. First 3 results:

Troponin in Stable Ischemic Heart Disease and Diabetes.
 

Author(s): Brendan M Everett, Maria Mori Brooks, Deepak L Bhatt

Journal: N. Engl. J. Med.. 2015 Nov;373(20):1978-9.

 

Last Updated: 12 Nov 2015

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Effect of PCI on Long-Term Survival in Patients with Stable Ischemic Heart Disease.
 

Author(s): Steven P Sedlis, Pamela M Hartigan, Koon K Teo, David J Maron, John A Spertus, G B John Mancini, William Kostuk, Bernard R Chaitman, Daniel Berman, Jeffrey D Lorin, Marcin Dada, William S Weintraub, William E Boden,

Journal: N. Engl. J. Med.. 2015 Nov;373(20):1937-46.

 

Percutaneous coronary intervention (PCI) relieves angina in patients with stable ischemic heart disease, but clinical trials have not shown that it improves survival. Between June 1999 and January 2004, we randomly assigned 2287 patients with stable ischemic heart disease to an initial ...

Last Updated: 12 Nov 2015

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Heart rate turbulence in patients with stable coronary artery disease and its relationship with the severity of the disease.
 

Author(s): Onur Baydar, Veysel Oktay, Ümit Yaşar Sinan, Uğur Coşkun, Ahmet Yıldız, Okay Abacı, Tevfik Gürmen, İnci Fıratlı

Journal: Turk Kardiyol Dern Ars. 2015 Oct;43(7):594-8.

 

Heart rate turbulence (HRT) indicates the impairment of cardiac autonomic function. With the literature containing insufficient information on HRT in stable coronary artery disease (CAD), this study aimed to investigate the role of HRT in patients with stable CAD.

Last Updated: 5 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heart Disease" returned 1261 free, full-text review articles on human participants. First 3 results:

[The Stem-Cell Application in Ischemic Heart Disease: Basic Principles, Specifics and Practical Experience from Clinical Studies].
 

Author(s): Marko Banović, Slobodan Obradović, Branko Beleslin

Journal: Srp Arh Celok Lek. ;143(7-8):487-93.

 

Longer life duration, different clinical presentations of coronary disease, as well as high incidence of comorbidity in patients with ischemic heart disease have led to an increase in the incidence of ischemic heart failure. Despite numerous and new treatment methods that act on different ...

Last Updated: 28 Oct 2015

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Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603,838 individuals.
 

Author(s): Mika Kivimäki, Markus Jokela, Solja T Nyberg, Archana Singh-Manoux, Eleonor I Fransson, Lars Alfredsson, Jakob B Bjorner, Marianne Borritz, Hermann Burr, Annalisa Casini, Els Clays, Dirk De Bacquer, Nico Dragano, Raimund Erbel, Goedele A Geuskens, Mark Hamer, Wendela E Hooftman, Irene L Houtman, Karl-Heinz Jöckel, France Kittel, Anders Knutsson, Markku Koskenvuo, Thorsten Lunau, Ida E H Madsen, Martin L Nielsen, Maria Nordin, Tuula Oksanen, Jan H Pejtersen, Jaana Pentti, Reiner Rugulies, Paula Salo, Martin J Shipley, Johannes Siegrist, Andrew Steptoe, Sakari B Suominen, Töres Theorell, Jussi Vahtera, Peter J M Westerholm, Hugo Westerlund, Dermot O'Reilly, Meena Kumari, G David Batty, Jane E Ferrie, Marianna Virtanen,

Journal: Lancet. 2015 Oct;386(10005):1739-46.

 

Long working hours might increase the risk of cardiovascular disease, but prospective evidence is scarce, imprecise, and mostly limited to coronary heart disease. We aimed to assess long working hours as a risk factor for incident coronary heart disease and stroke.

Last Updated: 7 Nov 2015

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Which individuals are at increased risk of pneumococcal disease and why? Impact of COPD, asthma, smoking, diabetes, and/or chronic heart disease on community-acquired pneumonia and invasive pneumococcal disease.
 

Author(s): Antoni Torres, Francesco Blasi, Nathalie Dartois, Murat Akova

Journal: Thorax. 2015 Oct;70(10):984-9.

 

Pneumococcal disease (including community-acquired pneumonia and invasive pneumococcal disease) poses a burden to the community all year round, especially in those with chronic underlying conditions. Individuals with COPD, asthma or who smoke, and those with chronic heart disease ...

Last Updated: 15 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Genetic Basis of Acquired Heart Disease in Africa
 

Status: Recruiting

Condition Summary: Rheumatic Heart Disease; Rheumatic Fever; Endomyocardial Fibrosis; Acquired Heart Disease

 

Last Updated: 14 Feb 2015

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The Genetic Basis of Congenital Heart Disease in Africa
 

Status: Recruiting

Condition Summary: Congenital Heart Disease; Heart Disease

 

Last Updated: 27 Jun 2015

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Erythropoietin to Prevent Unnecessary Transfusions In The Patients With Congenital Cyanotic Heart Disease - A Prospective Control Trial
 

Status: Not yet recruiting

Condition Summary: Cyanotic Congenital Heart Disease; Anemia; Cyanosis; Congenital Heart Disease

 

Last Updated: 30 Sep 2015

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