Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 985 free, full-text research articles on human participants. First 3 results:

New predictors of malignant ventricular arrhythmias in Chagas disease: searching for the holy grail.
 

Author(s): Márcio Vinícius Lins Barros

Journal: Rev. Soc. Bras. Med. Trop.. ;48(1):1-3.

 

Last Updated: 11 Apr 2015

Go To URL
Follow-up of an asymptomatic Chagas disease population of children after treatment with nifurtimox (Lampit) in a sylvatic endemic transmission area of Colombia.
 

Author(s): Fiorella Bianchi, Zulma Cucunubá, Felipe Guhl, Nadia Lorena González, Hector Freilij, Rubén Santiago Nicholls, Juan David Ramírez, Marleny Montilla, Astrid Carolina Flórez, Fernando Rosas, Victor Saavedra, Nubia Silva

Journal:

 

Chagas disease is an anthropozoonosis caused by Trypanosoma cruzi. Two drugs are currently used for the etiological treatment of the disease: Nifurtimox (Lampit) and Benznidazole. This study presents a quasi-experimental trial (non-control group) of sixty-two patients who were treated ...

Last Updated: 28 Feb 2015

Go To URL
Heart rate variability and Chagas heart disease.
 

Author(s): Marcos Antonio Almeida-Santos, Antonio Carlos Sobral Sousa

Journal: Arq. Bras. Cardiol.. 2015 Jan;104(1):90-1.

 

Last Updated: 26 Feb 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 124 free, full-text review articles on human participants. First 3 results:

Ventricular arrhythmias in Chagas disease.
 

Author(s): Marco Paulo Tomaz Barbosa, Andre Assis Lopes do Carmo, Manoel Otávio da Costa Rocha, Antonio Luiz Pinho Ribeiro

Journal: Rev. Soc. Bras. Med. Trop.. ;48(1):4-10.

 

Sudden death is one of the most characteristic phenomena of Chagas disease, and approximately one-third of infected patients develop life-threatening heart disease, including malignant ventricular arrhythmias. Fibrotic lesions secondary to chronic cardiomyopathy produce arrhythmogenic ...

Last Updated: 11 Apr 2015

Go To URL
Eco-bio-social research on community-based approaches for Chagas disease vector control in Latin America.
 

Author(s): Ricardo E Gürtler, Zaida E Yadon

Journal: Trans. R. Soc. Trop. Med. Hyg.. 2015 Feb;109(2):91-8.

 

This article provides an overview of three research projects which designed and implemented innovative interventions for Chagas disease vector control in Bolivia, Guatemala and Mexico. The research initiative was based on sound principles of community-based ecosystem management (ecohealth), ...

Last Updated: 21 Jan 2015

Go To URL
[Oral transmission of Trypanosoma cruzi : a new epidemiological scenario for Chagas' disease in Colombia and other South American countries].
 

Author(s): Karina Rueda, Jorge Eduardo Trujillo, Julio César Carranza, Gustavo Adolfo Vallejo

Journal: Biomedica. ;34(4):631-41.

 

Many cases of infection caused by the oral transmission of Trypanosoma cruzi have been reported during the last decade. These have been due to the contamination of food by faeces from sylvatic triatomines or by leakage from reservoirs in areas where domiciliated vectors have been ...

Last Updated: 16 Dec 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease; Trypanosomiasis, South American; South American Trypanosomiasis; Disease, Chagas

 

Last Updated: 14 Jul 2015

Go to URL
Syndecan-4 as a Biomarker in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease

 

Last Updated: 29 Apr 2013

Go to URL
Galectin-3 as a Biomarker in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease.

 

Last Updated: 25 Apr 2013

Go to URL