Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 959 free, full-text research articles on human participants. First 3 results:

Chagas disease in Latin America: an epidemiological update based on 2010 estimates.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Feb;90(6):33-43.

 

Last Updated: 11 Feb 2015

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[Trypanosoma cruzi in an immunocompromised patient. Reactivation of Chagas disease in a resident of La Rioja city, Argentina].
 

Author(s): Pablo N Castillo, Lucía N Salmaso, Gustavo Sosa Mangano, Blas N E Rombolá, Patricia A Cordoba

Journal: Rev. Argent. Microbiol.. ;46(4):378-9.

 

Last Updated: 10 Jan 2015

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Authors' reply: Vitamins in the treatment of chronic Chagas disease: adjuvant antiparasitary or antioxidant therapy?
 

Author(s): Mônica Coelho Andrade, Maria de Fátima Oliveira, Aparecida Tiemi Nagao-Dias, Ivo Castelo Branco Coêlho, Darlan da Silva Cândido, Erlane Chaves Freitas, Helena Lutéscia Luna Coelho, Fernando Schemelzer Moraes Bezerra

Journal: Rev. Soc. Bras. Med. Trop.. ;47(5):670-1.

 

Last Updated: 3 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 119 free, full-text review articles on human participants. First 3 results:

Chagas disease cardiomyopathy: immunopathology and genetics.
 

Author(s): Edecio Cunha-Neto, Christophe Chevillard

Journal: Mediators Inflamm.. 2014 ;2014():683230.

 

Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal inflammatory cardiomyopathy that occurs ...

Last Updated: 11 Sep 2014

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Chagas disease: still many unsolved issues.
 

Author(s): José M Álvarez, Raissa Fonseca, Henrique Borges da Silva, Cláudio R F Marinho, Karina R Bortoluci, Luiz R Sardinha, Sabrina Epiphanio, Maria Regina D'Império Lima

Journal: Mediators Inflamm.. 2014 ;2014():912965.

 

Over the past 20 years, the immune effector mechanisms involved in the control of Trypanosoma cruzi, as well as the receptors participating in parasite recognition by cells of the innate immune system, have been largely described. However, the main questions on the physiopathology ...

Last Updated: 8 Aug 2014

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Acute chagas disease: new global challenges for an old neglected disease.
 

Author(s): Daniela V Andrade, Kenneth J Gollob, Walderez O Dutra

Journal:

 

Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information concerning the chronic phase of human ...

Last Updated: 1 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Syndecan-4 as a Biomarker in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease

 

Last Updated: 29 Apr 2013

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Galectin-3 as a Biomarker in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease.

 

Last Updated: 25 Apr 2013

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Renal Denervation in Patients With Heart Failure Secondary to Chagas Disease
 

Status: Recruiting

Condition Summary: Heart Failure; Heart Failure, Systolic; Chagas Disease; Chagas Cardiomyopathy

 

Last Updated: 26 Mar 2014

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