Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 1149 free, full-text research articles on human participants. First 3 results:

Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients.
 

Author(s): Paulo Marcos Matta Guedes, Cléber Mesquita de Andrade, Daniela Ferreira Nunes, Nathalie de Sena Pereira, Tamyres Bernadete Dantas Queiroga, George Luiz Lins Machado-Coelho, Manuela Sales Lima Nascimento, Maria Adelaide Do-Valle-Matta, Antônia Cláudia Jácome da Câmara, Egler Chiari, Lúcia Maria da Cunha Galvão

Journal:

 

Ischemic strokes have been implicated as a cause of death in Chagas disease patients. Inflammation has been recognized as a key component in all ischemic processes, including the intravascular events triggered by vessel interruption, brain damage and repair. In this study, we evaluated ...

Last Updated: 27 Apr 2016

Go To URL
PREVALENCE OF CHAGAS DISEASE AMONG BLOOD DONOR CANDIDATES IN TRIANGULO MINEIRO, MINAS GERAIS STATE, BRAZIL.
 

Author(s): Patrícia da Silva Lopes, Eliezer Lucas Pires Ramos, César Gómez-Hernández, Gabriela Lícia Santos Ferreira, Karine Rezende-Oliveira

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2015 Dec;57(6):461-5.

 

Despite public health campaigns and epidemiological surveillance activities, Chagas disease remains a major health problem in Latin America. According to data from the World Health Organization, there are approximately 7-8 million people infected with Trypanosoma cruzi worldwide, ...

Last Updated: 7 Apr 2016

Go To URL
Development of a Novel Multiplex Immunoassay Multi-cruzi for the Serological Confirmation of Chagas Disease.
 

Author(s): Elodie Granjon, Marie-Laure Dichtel-Danjoy, Esber Saba, Ester Sabino, Lea Campos de Oliveira, Maan Zrein

Journal:

 

Chagas disease is due to the parasite Trypanosoma cruzi, a protist disseminated by a Triatome vector. This disease is endemic to Latin America and considered by WHO as one of the 17 world's neglected diseases. In Europe and in North America, imported cases are also detected, due to ...

Last Updated: 2 Apr 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 146 free, full-text review articles on human participants. First 3 results:

Control and management of congenital Chagas disease in Europe and other non-endemic countries: current policies and practices.
 

Author(s): Antoni Soriano-Arandes, Andrea Angheben, Nuria Serre-Delcor, Begoña Treviño-Maruri, Jordi Gómez I Prat, Yves Jackson

Journal: Trop. Med. Int. Health. 2016 May;21(5):590-6.

 

Identifying pregnant women infected with Trypanosoma cruzi is one of the major challenges for preventing and controlling Chagas disease (CD) in non-endemic countries. The aim of this paper was to perform a policy evaluation of the current practices of congenital Chagas disease (CCD) ...

Last Updated: 20 Apr 2016

Go To URL
Commercial enzyme-linked immunosorbent assay versuspolymerase chain reaction for the diagnosis of chronic Chagas disease: a systematic review and meta-analysis.
 

Author(s): Pedro Emmanuel Alvarenga Americano do Brasil, Rodolfo Castro, Liane de Castro

Journal: Mem. Inst. Oswaldo Cruz. 2016 Jan;111(1):1-19.

 

Chronic Chagas disease diagnosis relies on laboratory tests due to its clinical characteristics. The aim of this research was to review commercial enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) diagnostic test performance. Performance of commercial ELISA ...

Last Updated: 28 Jan 2016

Go To URL
Revisiting the Posttherapeutic Cure Criterion in Chagas Disease: Time for New Methods, More Questions, Doubts, and Polemics or Time to Change Old Concepts?
 

Author(s): Marta de Lana, Olindo Assis Martins-Filho

Journal: Biomed Res Int. 2015 ;2015():652985.

 

One of the most relevant issues beyond the effectiveness of etiological treatment of Chagas disease is the lack of consensual/feasible tools to identify and certify the definitive parasitological cure. Several methods of distinct natures (parasitological, serological, and molecular) ...

Last Updated: 20 Nov 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Prospective Study of a Pediatric Nifurtimox Formulation for Chagas' Disease
 

Status: Recruiting

Condition Summary: Chagas Disease

 

Last Updated: 6 Dec 2016

Go to URL
Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)
 

Status: Recruiting

Condition Summary: Chagas Disease With Heart Failure

 

Last Updated: 2 Sep 2015

Go to URL
Selenium Treatment and Chagasic Cardiopathy (STCC)
 

Status: Recruiting

Condition Summary: Chagas Disease

 

Last Updated: 9 Nov 2015

Go to URL