Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 1210 free, full-text research articles on human participants. First 3 results:

Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil.
 

Author(s): Lucia Elena Alvarado-Arnez, Angelica Martins Batista, Silvia Marinho Alves, Gloria Melo, Virgínia Maria Barros de Lorena, Cynthia C Cardoso, Isabela Resende Pereira, Cristina Carrazzone, Antonio G Pacheco, Wilson Oliveira, Milton Ozório Moraes, Joseli Lannes-Vieira

Journal:

 

The severity of chronic chagasic cardiomyopathy (CCC), the most frequent clinical outcome of Chagas disease (CD), has been associated with cytokine-enriched heart tissue inflammation, and high serum levels of transforming growth factor (TGFβ), interferon-gamma (IFNγ), and tumour ...

Last Updated: 31 Dec 1969

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Epidemiological and clinical profile of patients with Chagas disease in the Central-North area of Paraná, Southern Brazil.
 

Author(s): Aretuza Zaupa Gasparim, Carlos Edmundo Rodrigues Fontes, Diogo Francisco Rossoni, Max Jean de Ornelas Toledo

Journal: Rev. Soc. Bras. Med. Trop.. ;51(2):225-230.

 

Profiles of patients with Chagas disease in Paraná were studied.

Last Updated: 31 Dec 1969

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Acute Chagas disease in the state of Pará, Amazon Region: is it increasing?
 

Author(s): Valéria Regina Cavalcante Dos Santos, Juliana de Meis, Wilson Savino, Jorge Alberto Azevedo Andrade, José Ricardo Dos Santos Vieira, José Rodrigues Coura, Angela Cristina Verissimo Junqueira

Journal: Mem. Inst. Oswaldo Cruz. 2018 ;113(5):e170298.

 

Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 153 free, full-text review articles on human participants. First 3 results:

Biosensors to Diagnose Chagas Disease: A Brief Review.
 

Author(s): María-Isabel Rocha-Gaso, Luis-Jesús Villarreal-Gómez, Denis Beyssen, Frédéric Sarry, Marco-Antonio Reyna, Carlos-Napoleón Ibarra-Cerdeña

Journal:

 

Chagas disease (CD), which mostly affects those living in deprived areas, has become one of Latin America's main public health problems. Effective prevention of the disease requires early diagnosis, initiation of therapy, and regular blood monitoring of the infected individual. However, ...

Last Updated: 31 Dec 1969

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American trypanosomiasis, or Chagas disease, in Panama: a chronological synopsis of ecological and epidemiological research.
 

Author(s): Indra G Rodriguez, Jose R Loaiza

Journal:

 

American trypanosomiasis, or Chagas disease, is a growing public health problem in Panama, and further forest degradation due to human population growth is expected to worsen the situation. Most people infected with the parasite Trypanosoma cruzi are silently ill, and their life expectancy ...

Last Updated: 31 Dec 1969

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Experimental and Clinical Treatment of Chagas Disease: A Review.
 

Author(s): Policarpo Ademar Sales Junior, Israel Molina, Silvane Maria Fonseca Murta, Adrián Sánchez-Montalvá, Fernando Salvador, Rodrigo Corrêa-Oliveira, Cláudia Martins Carneiro

Journal: Am. J. Trop. Med. Hyg.. 2017 Nov;97(5):1289-1303.

 

Chagas disease (CD) is caused by the protozoan parasite that infects a broad range of triatomines and mammalian species, including man. It afflicts 8 million people in Latin America, and its incidence is increasing in nonendemic countries owing to rising international immigration ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease.
 

Status: Recruiting

Condition Summary: Chagas Disease; Trypanosoma Cruzi Infection

 

Last Updated: 16 Jun 2017

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Clinical Assessment, Neuroimaging and Immunomarkers in Chagas Disease Study (CLINICS)
 

Status: Recruiting

Condition Summary: Chagas Disease With Heart Failure

 

Last Updated: 1 Mar 2017

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Last Updated: 11 Jun 2018

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