Chagas Disease

Common Name(s)

Chagas Disease

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 876 free, full-text research articles on human participants. First 3 results:

Is autonomic function associated with left ventricular systolic function in Chagas heart disease patients undergoing treatment for heart failure?
 

Author(s): Lotte Raadschilders, Manoel Otavio da Costa Rocha, Lidiane Sousa, Jan Nouwen, Antonio Luiz Ribeiro

Journal: Rev. Soc. Bras. Med. Trop.. ;47(2):239-42.

 

The association between cardiac autonomic and left ventricular (LV) dysfunction in Chagas disease (ChD) is controversial.

Last Updated: 27 May 2014

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Evaluation of the Chagas disease control program in Açucena Municipality, Rio Doce Valley, State of Minas Gerais, Brazil.
 

Author(s): Adriana dos Santos, Rejane Balmant Letro, Vitor Antônio Lemos do Bem, Bernardino Vaz de Melo Azeredo, George Luiz Lins Machado Coelho, Liléia Diotaiuti, Girley Francisco Machado-de-Assis, Marta de Lana

Journal: Rev. Soc. Bras. Med. Trop.. ;47(2):186-92.

 

Açucena Municipality, Rio Doce Valley, State of Minas Gerais, Brazil temporarily (2001-2005) interrupted epidemiological surveillance for Chagas disease. The objective of this work was to evaluate the Chagas Disease Control Program (CDCP) in Açucena and to offer suggestions for ...

Last Updated: 27 May 2014

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Neglected parasitic infections in the United States: Chagas disease.
 

Author(s): Susan P Montgomery, Michelle C Starr, Paul T Cantey, Morven S Edwards, Sheba K Meymandi

Journal: Am. J. Trop. Med. Hyg.. 2014 May;90(5):814-8.

 

Chagas disease, which is caused by the protozoan parasite Trypanosoma cruzi, can lead to severe cardiac and gastrointestinal disease. Most persons acquire this infection through contact with vector bugs carrying T. cruzi in endemic areas of Latin America. Infection can also be acquired ...

Last Updated: 8 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 107 free, full-text review articles on human participants. First 3 results:

An unfolding tragedy of Chagas disease in North America.
 

Author(s): Peter J Hotez, Eric Dumonteil, Miguel Betancourt Cravioto, Maria Elena Bottazzi, Roberto Tapia-Conyer, Sheba Meymandi, Unni Karunakara, Isabela Ribeiro, Rachel M Cohen, Bernard Pecoul

Journal:

 

Last Updated: 8 Nov 2013

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[Control of Chagas disease in pregnant Latin-American women and her children].
 

Author(s): Francisco J Merino, Rocío Martínez-Ruiz, Iciar Olabarrieta, Paloma Merino, Silvia García-Bujalance, Teresa Gastañaga, María Flores-Chavez,

Journal: Rev Esp Quimioter. 2013 Sep;26(3):253-60.

 

Chagas disease is a chronic and systemic infection caused by Trypanosoma cruzi. According to estimates from WHO, 10 million people are affected by this parasite. In the last years, birthrate among the immigrant women from Latin America settled in the Comunidad Autónoma de Madrid ...

Last Updated: 1 Oct 2013

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Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes.
 

Author(s): Christiane Maria Ayo, Márcia Machado de Oliveira Dalalio, Jeane Eliete Laguila Visentainer, Pâmela Guimarães Reis, Emília Ângela Sippert, Luciana Ribeiro Jarduli, Hugo Vicentin Alves, Ana Maria Sell

Journal: Biomed Res Int. 2013 ;2013():284729.

 

Chagas disease, which is caused by the flagellate parasite Trypanosoma cruzi, affects 8-10 million people in Latin America. The disease is endemic and is characterised by acute and chronic phases that develop in the indeterminate, cardiac, and/or gastrointestinal forms. The immune ...

Last Updated: 26 Sep 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

MicroRNAs as Biomarkers in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease

 

Last Updated: 25 Apr 2013

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Study Of Nifurtimox Transfer Into Breastmilk In Lactating Women With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease; Lactation

 

Last Updated: 5 Dec 2012

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Study of Benznidazole Transfer Into Breastmilk in Lactating Women With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease; Lactation

 

Last Updated: 5 Dec 2012

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