Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 975 free, full-text research articles on human participants. First 3 results:

New predictors of malignant ventricular arrhythmias in Chagas disease: searching for the holy grail.
 

Author(s): Márcio Vinícius Lins Barros

Journal: Rev. Soc. Bras. Med. Trop.. ;48(1):1-3.

 

Last Updated: 11 Apr 2015

Go To URL
Heart rate variability and Chagas heart disease.
 

Author(s): Marcos Antonio Almeida-Santos, Antonio Carlos Sobral Sousa

Journal: Arq. Bras. Cardiol.. 2015 Jan;104(1):90-1.

 

Last Updated: 26 Feb 2015

Go To URL
Chagas disease in Latin America: an epidemiological update based on 2010 estimates.
 

Author(s):

Journal: Wkly. Epidemiol. Rec.. 2015 Feb;90(6):33-43.

 

Last Updated: 11 Feb 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 121 free, full-text review articles on human participants. First 3 results:

Ventricular arrhythmias in Chagas disease.
 

Author(s): Marco Paulo Tomaz Barbosa, Andre Assis Lopes do Carmo, Manoel Otávio da Costa Rocha, Antonio Luiz Pinho Ribeiro

Journal: Rev. Soc. Bras. Med. Trop.. ;48(1):4-10.

 

Sudden death is one of the most characteristic phenomena of Chagas disease, and approximately one-third of infected patients develop life-threatening heart disease, including malignant ventricular arrhythmias. Fibrotic lesions secondary to chronic cardiomyopathy produce arrhythmogenic ...

Last Updated: 11 Apr 2015

Go To URL
Ecoepidemiology, short history and control of Chagas disease in the endemic countries and the new challenge for non-endemic countries.
 

Author(s): José Rodrigues Coura, Pedro Albajar Viñas, Angela Cv Junqueira

Journal: Mem. Inst. Oswaldo Cruz. 2014 Nov;109(7):856-62.

 

Chagas disease is maintained in nature through the interchange of three cycles: the wild, peridomestic and domestic cycles. The wild cycle, which is enzootic, has existed for millions of years maintained between triatomines and wild mammals. Human infection was only detected in mummies ...

Last Updated: 21 Nov 2014

Go To URL
Chagas disease cardiomyopathy: immunopathology and genetics.
 

Author(s): Edecio Cunha-Neto, Christophe Chevillard

Journal: Mediators Inflamm.. 2014 ;2014():683230.

 

Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), a particularly lethal inflammatory cardiomyopathy that occurs ...

Last Updated: 11 Sep 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease; Trypanosomiasis, South American; South American Trypanosomiasis; Disease, Chagas

 

Last Updated: 14 Jul 2015

Go to URL
Syndecan-4 as a Biomarker in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease

 

Last Updated: 29 Apr 2013

Go to URL
Galectin-3 as a Biomarker in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease.

 

Last Updated: 25 Apr 2013

Go to URL