Chagas Disease

Common Name(s)

Chagas Disease, American trypanosomiasis

Chagas disease is caused by the parasite, Trypanosoma cruzi. When a triatomine bug (commonly known as a "kissing bug") infected with this parasite bites you, usually on your face, it leaves behind infected waste which can be spread into your eyes, nose, or a wound. Chagas disease can also spread through contaminated food, a blood transfusion, a donated organ or from mother to baby during pregnancy. Symptoms can include fever, flu-like symptoms, a rash or swollen eyelid. Early symptoms usually go away but if not treated, the infection can later cause serious intestinal and heart problems. Chagas disease is common in Latin America but not in the United States.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chagas Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chagas Disease" returned 1044 free, full-text research articles on human participants. First 3 results:

Chagas' Disease.
 

Author(s): Caryn Bern

Journal: N. Engl. J. Med.. 2015 Nov;373(19):1882.

 

Last Updated: 5 Nov 2015

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Neglect of a Neglected Disease in Italy: The Challenge of Access-to-Care for Chagas Disease in Bergamo Area.
 

Author(s): Ernestina Carla Repetto, Rony Zachariah, Ajay Kumar, Andrea Angheben, Federico Gobbi, Mariella Anselmi, Ahmad Al Rousan, Carlota Torrico, Rosa Ruiz, Gabriel Ledezma, Maria Chiara Buoninsegna, Mohammed Khogali, Rafael Van den Bergh, Gianfranco De Maio, Ada Maristella Egidi, Barbara Maccagno, Silvia Garelli

Journal:

 

Chagas disease (CD) represents a growing problem in Europe; Italy is one of the most affected countries but there is no national framework for CD and access-to-care is challenging. In 2012 Médecins Sans Frontières (MSF) started an intervention in Bergamo province, where many people ...

Last Updated: 26 Sep 2015

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[Guiding the etiological treatment of Chagas disease].
 

Author(s): Sergio Sosa Estani, Jaime Altcheh, Adelina Riarte, Héctor Freilij, Marisa Fernandez, Susana Lloveras, Ana Pereiro, Luis Gerardo Castellano, Roberto Salvatella, Rubén S Nicholls,

Journal: Medicina (B Aires). 2015 ;75(4):270-1.

 

Last Updated: 5 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chagas Disease" returned 129 free, full-text review articles on human participants. First 3 results:

Chagas disease in the State of Amazonas: history, epidemiological evolution, risks of endemicity and future perspectives.
 

Author(s): Maria das Graças Vale Barbosa, João Marcos Bemfica Barbosa Ferreira, Ana Ruth Lima Arcanjo, Rosa Amélia Gonçalves Santana, Laylah Kelre Costa Magalhães, Laise Kelma Costa Magalhães, Daniel Testa Mota, Nelson Ferreira Fé, Wuelton Marcelo Monteiro, Henrique Silveira, Jorge Augusto de Oliveira Guerra

Journal: Rev. Soc. Bras. Med. Trop.. 2015 ;48 Suppl 1():27-33.

 

Chagas disease (CD) is a parasitic infection that originated in the Americas and is caused by Trypanosoma cruzi. In the last few years, the disease has spread to countries in North America, Asia and Europe due to the migration of Latin Americans. In the Brazilian Amazon, CD has an ...

Last Updated: 11 Jun 2015

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Prophylactic and therapeutic DNA vaccines against Chagas disease.
 

Author(s): Minerva Arce-Fonseca, Martha Rios-Castro, Silvia del Carmen Carrillo-Sánchez, Mariana Martínez-Cruz, Olivia Rodríguez-Morales

Journal:

 

Chagas disease is a zoonosis caused by Trypanosoma cruzi in which the most affected organ is the heart. Conventional chemotherapy has a very low effectiveness; despite recent efforts, there is currently no better or more effective treatment available. DNA vaccines provide a new alternative ...

Last Updated: 18 Apr 2015

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Ventricular arrhythmias in Chagas disease.
 

Author(s): Marco Paulo Tomaz Barbosa, Andre Assis Lopes do Carmo, Manoel Otávio da Costa Rocha, Antonio Luiz Pinho Ribeiro

Journal: Rev. Soc. Bras. Med. Trop.. ;48(1):4-10.

 

Sudden death is one of the most characteristic phenomena of Chagas disease, and approximately one-third of infected patients develop life-threatening heart disease, including malignant ventricular arrhythmias. Fibrotic lesions secondary to chronic cardiomyopathy produce arrhythmogenic ...

Last Updated: 11 Apr 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease; Trypanosomiasis, South American; South American Trypanosomiasis; Disease, Chagas

 

Last Updated: 14 Jul 2015

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Renal Denervation in Patients With Heart Failure Secondary to Chagas Disease
 

Status: Recruiting

Condition Summary: Heart Failure; Heart Failure, Systolic; Chagas Disease; Chagas Cardiomyopathy

 

Last Updated: 26 Mar 2014

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Reveal Chagas: Clinical Evidence of the Implantable Cardiac Monitor in Patients With Chagas Disease
 

Status: Recruiting

Condition Summary: Chagas Disease; Heart Diseases

 

Last Updated: 3 Dec 2013

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