Cervical Dystonia

Common Name(s)

Cervical Dystonia

Cervical dystonia is a focal dystonia characterized by excessive pulling of the muscles of the neck and shoulder resulting in abnormal movements of the head. Most commonly, the head turns to one side or the other. Tilting sideways, or to the back or front may also occur.  The turning or tilting movements may be accompanied by tremor and/or soreness of the muscles of the neck and shoulders.  Cervical dystonia can occur at any age, although most individuals first experience symptoms in middle age. It often begins slowly and usually reaches a plateau over a few months or years. Treatment may include local intramuscular injections of botulinum toxin, analgesics, benzodiazepines (anti-anxiety medications), anticholinergics, physical therapy, or surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical Dystonia" for support, advocacy or research.

The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

Last Updated: 15 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical Dystonia" for support, advocacy or research.

The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

https://www.dystonia-parkinson.org

Last Updated: 15 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cervical Dystonia" returned 85 free, full-text research articles on human participants. First 3 results:

Factors affecting the health-related quality of life of patients with cervical dystonia and impact of treatment with abobotulinumtoxinA (Dysport): results from a randomised, double-blind, placebo-controlled study.
 

Author(s): Margaret Mordin, Catherine Masaquel, Chandra Abbott, Catherine Copley-Merriman

Journal:

 

To describe the health-related quality of life (HRQOL) burden of cervical dystonia (CD) and report on the HRQOL and patient perception of treatment benefits of abobotulinumtoxinA (Dysport).

Last Updated: 17 Oct 2014

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IncobotulinumtoxinA (Xeomin®) injected for blepharospasm or cervical dystonia according to patient needs is well tolerated.
 

Author(s): Virgilio Gerald H Evidente, Daniel Truong, Joseph Jankovic, Cynthia L Comella, Susanne Grafe, Angelika Hanschmann

Journal: J. Neurol. Sci.. 2014 Nov;346(1-2):116-20.

 

Typically, botulinum toxin injections for blepharospasm or cervical dystonia (CD) are administered at approximately 3-month intervals, reflecting concerns that shorter intervals might increase the risk of adverse events (AEs) and development of neutralizing antibodies. These post-hoc ...

Last Updated: 2 Dec 2014

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The physical, social and emotional aspects are the most affected in the quality of life of the patients with cervical dystonia.
 

Author(s): Roberta Weber Werle, Sibele Yoko Mattozo Takeda, Marise Bueno Zonta, Ana Tereza Bittencourt Guimarães, Hélio Afonso Ghizoni Teive

Journal: Arq Neuropsiquiatr. 2014 Jun;72(6):405-10.

 

Describe the functional, clinical and quality of life (QoL) profiles in patients with cervical dystonia (CD) with residual effect or without effect of botulinum toxin (BTX), as well as verify the existence of correlation between the level of motor impairment, pain and QoL.

Last Updated: 26 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cervical Dystonia" returned 6 free, full-text review articles on human participants. First 3 results:

Donepezil-induced cervical dystonia in Alzheimer's disease: a case report and literature review of dystonia due to cholinesterase inhibitors.
 

Author(s): Ken Ikeda, Masaru Yanagihashi, Masahiro Sawada, Sayori Hanashiro, Kiyokazu Kawabe, Yasuo Iwasaki

Journal: Intern. Med.. 2014 ;53(9):1007-10.

 

We herein report an 81-year-old woman with Alzheimer's disease (AD) in who donepezil, a cholinesterase inhibitor (ChEI), caused cervical dystonia. The patient had a two-year history of progressive memory disturbance fulfilling the NINCDS-ADRDA criteria for probable AD. Mini-Mental ...

Last Updated: 5 May 2014

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Systematic review and meta-analysis of the duration of clinical effect of onabotulinumtoxinA in cervical dystonia.
 

Author(s): Wallace A Marsh, Deirdre M Monroe, Mitchell F Brin, Conor J Gallagher

Journal:

 

Botulinum toxins are considered first-line therapy for treatment of cervical dystonia (CD) and must be injected on a repeat basis. Understanding the duration of clinical benefit of botulinum toxins and its impact on health care utilization are thus important in the contemporary environment. ...

Last Updated: 3 Jun 2014

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Rating scales for cervical dystonia: a critical evaluation of tools for outcome assessment of botulinum toxin therapy.
 

Author(s): Wolfgang H Jost, Harald Hefter, Andrea Stenner, Gerhard Reichel

Journal: J Neural Transm. 2013 Mar;120(3):487-96.

 

Botulinum neurotoxin is the therapy of choice for all forms of cervical dystonia (CD), but treatment regimens still vary considerably. The interpretation of treatment outcome is mainly based on the clinical experience and on the scientific value of the rating scales applied. The aim ...

Last Updated: 19 Feb 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

ASIS for Botox in Cervical Dystonia
 

Status: Not yet recruiting

Condition Summary: Cervical Dystonia Adults ,; Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus.

 

Last Updated: 22 Jun 2015

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Last Updated: 16 Apr 2015

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tDCS in Cervical Dystonia
 

Status: Not yet recruiting

Condition Summary: Cervical Dystonia

 

Last Updated: 19 Mar 2015

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