Cervical Dystonia

Common Name(s)

Cervical Dystonia

Cervical dystonia is a focal dystonia characterized by excessive pulling of the muscles of the neck and shoulder resulting in abnormal movements of the head. Most commonly, the head turns to one side or the other. Tilting sideways, or to the back or front may also occur.  The turning or tilting movements may be accompanied by tremor and/or soreness of the muscles of the neck and shoulders.  Cervical dystonia can occur at any age, although most individuals first experience symptoms in middle age. It often begins slowly and usually reaches a plateau over a few months or years. Treatment may include local intramuscular injections of botulinum toxin, analgesics, benzodiazepines (anti-anxiety medications), anticholinergics, physical therapy, or surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical Dystonia" for support, advocacy or research.

The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cervical Dystonia" for support, advocacy or research.

The Bachmann-Strauss Dystonia & Parkinson Foundation

The Bachmann-Strauss Dystonia & Parkinson Foundation was established in 1995 to find better treatments and cures for the movement disorders dystonia and Parkinson's disease and to provide medical and patient information.

https://www.dystonia-parkinson.org

Last Updated: 15 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cervical Dystonia" returned 83 free, full-text research articles on human participants. First 3 results:

The physical, social and emotional aspects are the most affected in the quality of life of the patients with cervical dystonia.
 

Author(s): Roberta Weber Werle, Sibele Yoko Mattozo Takeda, Marise Bueno Zonta, Ana Tereza Bittencourt Guimarães, Hélio Afonso Ghizoni Teive

Journal: Arq Neuropsiquiatr. 2014 Jun;72(6):405-10.

 

Describe the functional, clinical and quality of life (QoL) profiles in patients with cervical dystonia (CD) with residual effect or without effect of botulinum toxin (BTX), as well as verify the existence of correlation between the level of motor impairment, pain and QoL.

Last Updated: 26 Jun 2014

Go To URL
Normal motor adaptation in cervical dystonia: a fundamental cerebellar computation is intact.
 

Author(s): Anna Sadnicka, Bansi Patani, Tabish A Saifee, Panagiotis Kassavetis, Isabel Pareés, Prasad Korlipara, Kailash P Bhatia, John C Rothwell, Joseph M Galea, Mark J Edwards

Journal: Cerebellum. 2014 Oct;13(5):558-67.

 

The potential role of the cerebellum in the pathophysiology of dystonia has become a focus of recent research. However, direct evidence for a cerebellar contribution in humans with dystonia is difficult to obtain. We examined motor adaptation, a test of cerebellar function, in 20 ...

Last Updated: 5 Sep 2014

Go To URL
Cervical dystonia and pain: characteristics and treatment patterns from CD PROBE (Cervical Dystonia Patient Registry for Observation of OnabotulinumtoxinA Efficacy).
 

Author(s): P David Charles, Charles H Adler, Mark Stacy, Cynthia Comella, Joseph Jankovic, Aubrey Manack Adams, Marc Schwartz, Mitchell F Brin

Journal: J. Neurol.. 2014 Jul;261(7):1309-19.

 

To compare profiles of subjects with and without cervical dystonia (CD)-associated pain, to evaluate the contribution of pain and the motor component of CD on quality of life, and to compare the initial botulinum toxin treatment paradigm between pain groups, baseline data were used ...

Last Updated: 15 Jul 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cervical Dystonia" returned 6 free, full-text review articles on human participants. First 3 results:

Donepezil-induced cervical dystonia in Alzheimer's disease: a case report and literature review of dystonia due to cholinesterase inhibitors.
 

Author(s): Ken Ikeda, Masaru Yanagihashi, Masahiro Sawada, Sayori Hanashiro, Kiyokazu Kawabe, Yasuo Iwasaki

Journal: Intern. Med.. 2014 ;53(9):1007-10.

 

We herein report an 81-year-old woman with Alzheimer's disease (AD) in who donepezil, a cholinesterase inhibitor (ChEI), caused cervical dystonia. The patient had a two-year history of progressive memory disturbance fulfilling the NINCDS-ADRDA criteria for probable AD. Mini-Mental ...

Last Updated: 5 May 2014

Go To URL
Systematic review and meta-analysis of the duration of clinical effect of onabotulinumtoxinA in cervical dystonia.
 

Author(s): Wallace A Marsh, Deirdre M Monroe, Mitchell F Brin, Conor J Gallagher

Journal:

 

Botulinum toxins are considered first-line therapy for treatment of cervical dystonia (CD) and must be injected on a repeat basis. Understanding the duration of clinical benefit of botulinum toxins and its impact on health care utilization are thus important in the contemporary environment. ...

Last Updated: 3 Jun 2014

Go To URL
Rating scales for cervical dystonia: a critical evaluation of tools for outcome assessment of botulinum toxin therapy.
 

Author(s): Wolfgang H Jost, Harald Hefter, Andrea Stenner, Gerhard Reichel

Journal: J Neural Transm. 2013 Mar;120(3):487-96.

 

Botulinum neurotoxin is the therapy of choice for all forms of cervical dystonia (CD), but treatment regimens still vary considerably. The interpretation of treatment outcome is mainly based on the clinical experience and on the scientific value of the rating scales applied. The aim ...

Last Updated: 19 Feb 2013

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

ASIS for Botox in Cervical Dystonia
 

Status: Not yet recruiting

Condition Summary: Cervical Dystonia Adults ,; Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus.

 

Last Updated: 26 Feb 2014

Go to URL

Last Updated: 16 Apr 2015

Go to URL
Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia
 

Status: Recruiting

Condition Summary: Cervical Dystonia

 

Last Updated: 8 Jan 2015

Go to URL