Cerebellar Ataxia

Common Name(s)

Cerebellar Ataxia

Cerebellar Ataxia is a condition in which damage, degeneration, or loss of nerve cells in the cerebellum (part of the brain that controls movement), results in balance problems and difficulty coordinating complex movements (ataxia). Cerebellar ataxia can be caused by: spinal cord or nerve damage, head trauma, stroke, cerebral palsy, multiple sclerosis, tumors, or complications from chickenpox. Symptoms of this condition may include poor coordination, change in speech, involuntary eye movements, and difficulty with fine motor skills. There is no specific treatment for this condition, but symptoms can be alleviated by using adaptive devices (such as canes or modified eating utensils), and therapy (physical, speech, etc.).

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Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cerebellar Ataxia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cerebellar Ataxia" returned 239 free, full-text research articles on human participants. First 3 results:

Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia.
 

Author(s): Yuting Shi, Junling Wang, Jia-Da Li, Haigang Ren, Wenjuan Guan, Miao He, Weiqian Yan, Ying Zhou, Zhengmao Hu, Jianguo Zhang, Jingjing Xiao, Zheng Su, Meizhi Dai, Jun Wang, Hong Jiang, Jifeng Guo, Yafang Zhou, Fufeng Zhang, Nan Li, Juan Du, Qian Xu, Yacen Hu, Qian Pan, Lu Shen, Guanghui Wang, Kun Xia, Zhuohua Zhang, Beisha Tang

Journal:

 

Autosomal recessive cerebellar ataxias are a group of neurodegenerative disorders that are characterized by complex clinical and genetic heterogeneity. Although more than 20 disease-causing genes have been identified, many patients are still currently without a molecular diagnosis. ...

Last Updated: 6 Dec 2013

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Acute cerebellar ataxia associated with enteric fever in a child: a case report.
 

Author(s): Faruk İncecik, M Özlem Hergüner, Gülen Mert, Derya Alabaz, Şakir Altunbaşak

Journal: Turk. J. Pediatr.. ;55(4):441-2.

 

Enteric fever is a common infectious disease of the tropical world. Characteristic presenting features include fever, relative bradycardia, diarrhea or constipation, and abdominal pain. Central nervous system involvement is not rare and has a wide spectrum of presentation in enteric ...

Last Updated: 2 Dec 2013

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Autosomal-recessive cerebellar ataxia caused by a novel ADCK3 mutation that elongates the protein: clinical, genetic and biochemical characterisation.
 

Author(s): Yo-Tsen Liu, Joshua Hersheson, Vincent Plagnol, Katherine Fawcett, Kate E C Duberley, Elisavet Preza, Iain P Hargreaves, Annapurna Chalasani, Matilde Laurá, Nick W Wood, Mary M Reilly, Henry Houlden

Journal: J. Neurol. Neurosurg. Psychiatr.. 2014 May;85(5):493-8.

 

The autosomal-recessive cerebellar ataxias (ARCA) are a clinically and genetically heterogeneous group of neurodegenerative disorders. The large number of ARCA genes leads to delay and difficulties obtaining an exact diagnosis in many patients and families. Ubiquinone (CoQ10) deficiency ...

Last Updated: 14 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cerebellar Ataxia" returned 12 free, full-text review articles on human participants. First 3 results:

[Acute cerebellar ataxia in childhood].
 

Author(s): Yaline Betancourt Fursow, Juan Carlos Jiménez León, Cristina S Jiménez Betancourt

Journal: Medicina (B Aires). 2013 ;73 Suppl 1():30-7.

 

Acute cerebellar ataxia of childhood is the most frequent neurological complication of chickenpox virus infection. Acute cerebellar ataxia is categorized within the group of acute postinfectious complications. The aims of this study were: (I) to evaluate the clinical presentation, ...

Last Updated: 27 Sep 2013

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Joubert syndrome: congenital cerebellar ataxia with the molar tooth.
 

Author(s): Marta Romani, Alessia Micalizzi, Enza Maria Valente

Journal: Lancet Neurol. 2013 Sep;12(9):894-905.

 

Joubert syndrome is a congenital cerebellar ataxia with autosomal recessive or X-linked inheritance, the diagnostic hallmark of which is a unique cerebellar and brainstem malformation recognisable on brain imaging-the so-called molar tooth sign. Neurological signs are present from ...

Last Updated: 16 Aug 2013

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Autosomal dominant cerebellar ataxia type III: a review of the phenotypic and genotypic characteristics.
 

Author(s): Shinsuke Fujioka, Christina Sundal, Zbigniew K Wszolek

Journal:

 

Autosomal Dominant Cerebellar Ataxia (ADCA) Type III is a type of spinocerebellar ataxia (SCA) classically characterized by pure cerebellar ataxia and occasionally by non-cerebellar signs such as pyramidal signs, ophthalmoplegia, and tremor. The onset of symptoms typically occurs ...

Last Updated: 30 Jan 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Study to Evaluate the Safety and Efficacy BMMNC in Cerebellar Ataxia
 

Status: Recruiting

Condition Summary: Cerebellar Ataxia

 

Last Updated: 16 Sep 2014

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SPATAX: Clinical and Genetic Analysis of Cerebellar Ataxias and Spastic Paraplegias
 

Status: Recruiting

Condition Summary: Cerebellar Ataxias; Spastic Paraplegias

 

Last Updated: 26 Mar 2012

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Efficacy of Riluzole in Hereditary Cerebellar Ataxia
 

Status: Recruiting

Condition Summary: Cerebellar Ataxia

 

Last Updated: 19 Jul 2011

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