Cerebellar Ataxia

Common Name(s)

Cerebellar Ataxia

Cerebellar Ataxia is a condition in which damage, degeneration, or loss of nerve cells in the cerebellum (part of the brain that controls movement), results in balance problems and difficulty coordinating complex movements (ataxia). Cerebellar ataxia can be caused by: spinal cord or nerve damage, head trauma, stroke, cerebral palsy, multiple sclerosis, tumors, or complications from chickenpox. Symptoms of this condition may include poor coordination, change in speech, involuntary eye movements, and difficulty with fine motor skills. There is no specific treatment for this condition, but symptoms can be alleviated by using adaptive devices (such as canes or modified eating utensils), and therapy (physical, speech, etc.).

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cerebellar Ataxia" for support, advocacy or research.

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cerebellar Ataxia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cerebellar Ataxia" returned 277 free, full-text research articles on human participants. First 3 results:

Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial.
 

Author(s): Katharina Feil, Christine Adrion, Julian Teufel, Sylvia Bösch, Jens Claassen, Ilaria Giordano, Holger Hengel, Heike Jacobi, Thomas Klockgether, Thomas Klopstock, Wolfgang Nachbauer, Ludger Schöls, Claudia Stendel, Ellen Uslar, Bart van de Warrenburg, Ingrid Berger, Ivonne Naumann, Otmar Bayer, Hans-Helge Müller, Ulrich Mansmann, Michael Strupp

Journal:

 

Cerebellar ataxia (CA) is a frequent and often disabling condition that impairs motor functioning and impacts on quality of life (QoL). No medication has yet been proven effective for the symptomatic or even causative treatment of hereditary or non-hereditary, non-acquired CA. So ...

Last Updated: 10 Jan 2017

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Unusual phenotype of pathologically confirmed progressive supranuclear palsy with autonomic dysfunction and cerebellar ataxia: Case report.
 

Author(s): Katerina Mensikova, Lucie Tuckova, Jiri Ehrmann, Petr Kanovsky

Journal: Medicine (Baltimore). 2016 Nov;95(46):e5237.

 

Based on the results of recent multicenter clinical-pathological studies, it seems that the clinical heterogeneity of progressive supranuclear palsy (PSP) is much broader than previously thought. We will report 2 cases of patients with unusual manifestation of pathologically confirmed PSP.

Last Updated: 18 Nov 2016

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Prevalence of Autoantibodies and the Efficacy of Immunotherapy for Autoimmune Cerebellar Ataxia.
 

Author(s): Kazunori Nanri, Misaki Okuma, Saki Sato, Makoto Yoneda, Takeshi Taguchi, Hiroshi Mitoma, Junji Yamada, Sakae Unezaki, Tetsuo Nagatani, Shiho Otsubo, Mayumi Sugawara, Nobuyuki Tanaka, Hidehiro Mizusawa

Journal: Intern. Med.. 2016 ;55(5):449-54.

 

Autoimmune cerebellar ataxias were recently reported to be treatable. However, the proportion of patients with cortical cerebellar atrophy of unknown etiology with autoimmune-associated cerebellar ataxia and the actual effectiveness of immunotherapy in these diseases remain unknown.

Last Updated: 3 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cerebellar Ataxia" returned 17 free, full-text review articles on human participants. First 3 results:

'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr/DNER, other antibodies, diagnostic pitfalls, summary and outlook.
 

Author(s): S Jarius, B Wildemann

Journal:

 

Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis. While some of them target nuclear antigens present in all or most CNS ...

Last Updated: 17 Sep 2015

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'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca/ARHGAP26 and anti-VGCC.
 

Author(s): S Jarius, B Wildemann

Journal:

 

Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis. While some of them target nuclear antigens present in all or most CNS ...

Last Updated: 17 Sep 2015

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'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII.
 

Author(s): S Jarius, B Wildemann

Journal:

 

Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis. While some of them target nuclear antigens present in all or most CNS ...

Last Updated: 17 Sep 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Augmenting Balance in Individuals With Cerebellar Ataxias
 

Status: Recruiting

Condition Summary: Cerebellar Ataxia

 

Last Updated: 21 Sep 2016

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Sporadic Degenerative Ataxia With Adult Onset: Natural History Study
 

Status: Recruiting

Condition Summary: Late Onset Sporadic Cerebellar Ataxia

 

Last Updated: 9 Mar 2016

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