Centrotemporal Epilepsy

Common Name(s)

Centrotemporal Epilepsy, Benign rolandic epilepsy

Centrotemporal epilepsy, also known as benign rolandic epilepsy, is a form of epilepsy where seizures affect the face and sometimes the body. This form of epilepsy does not affect adults, and seizures typically begin in affected children around the age of six to eight years old.

"Rolandic" refers to the region of the brain in which the seizures begin; this area of the brain is what controls the face. Rolandic seizures are considered "partial" seizures because they begin in a specific region of the brain rather than involving the entire brain. The seizures resulting from centrotemporal epilepsy are generally mild, and may include facial or cheek twitching, numbness or tingling in the tongue or face, difficulty speaking, and drooling due to the inability to not be able to control the mouth temporarily. Many times, rolandic seizures occur during sleep, so they may go unnoticed. Children with rolandic epilepsy may also have learning difficulties and behavioral issues.

In about half of children with this condition, the seizures begin in the rolandic region of the brain, but then spread to the rest of the brain. This is referred to as secondary generalized seizures (or tonic-clonic seizures) and symptoms are more severe and include full body muscle clenching, convulsions, unresponsiveness, and confusion or disorientation after the seizure is over.

Diagnosis of benign rolandic epilepsy is based on the pattern of seizures as well as testing which includes EEG, MRI and neurological exams. If symptoms remain mild, no treatment is needed as the seizures are often harmless and do not occur frequently. Symptoms that may suggest treatment would include learning difficulties, behavioral problems, daytime seizures or seizures that are frequent or become more severe. Anti-seizure medications are available in some cases. Please see a specialist if your child is having these symptoms to discuss the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Centrotemporal Epilepsy" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Centrotemporal Epilepsy" returned 62 free, full-text research articles on human participants. First 3 results:

Clinical features of benign epilepsy of childhood with centrotemporal spikes in chinese children.
 

Author(s): Meng-Jia Liu, Xiao-Jun Su, Xiu-Yu Shi Md, Ge-Fei Wu, Yu-Qin Zhang, Li Gao, Wei Wang, Jian-Xiang Liao, Hua Wang, Jian-Ning Mai, Jing-Yun Gao, Xiao-Mei Shu, Shao-Ping Huang, Li Zhang, Li-Ping Zou

Journal: Medicine (Baltimore). 2017 Jan;96(4):e5623.

 

This multicenter clinical trial was conducted to examine current practice of benign epilepsy with centrotemporal spikes and especially address the question that in what circumstances 1 antiepileptic drug (AED) should be preferred.Twenty-five medical centers participate in this clinical ...

Last Updated: 25 Jan 2017

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Impact of frequency and lateralization of interictal discharges on neuropsychological and fine motor status in children with benign epilepsy with centrotemporal spikes.
 

Author(s): Jennifer Vannest, Jeffrey R Tenney, Mekibib Altaye, Anna W Byars, Caroline Spencer, Thomas C Maloney, Jerzy P Szaflarski, Diego Morita, Tracy A Glauser

Journal: Epilepsia. 2016 Aug;57(8):e161-7.

 

Despite a positive prognosis for seizure remission, children with benign epilepsy with centrotemporal spikes (BECTS) have been reported to exhibit subtle neuropsychological difficulties. We examined the relationship between patterns of centrotemporal spikes (the typical electroencephalography ...

Last Updated: 3 Aug 2016

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Altered functional and effective connectivity in anticorrelated intrinsic networks in children with benign childhood epilepsy with centrotemporal spikes.
 

Author(s): Cheng Luo, Fei Yang, Jiayan Deng, Yaodan Zhang, Changyue Hou, Yue Huang, Weifang Cao, Jianjun Wang, Ruhui Xiao, Nanlin Zeng, Xiaoming Wang, Dezhong Yao

Journal: Medicine (Baltimore). 2016 Jun;95(24):e3831.

 

There are 2 intrinsic networks in the human brain: the task positive network (TPN) and task negative network (alternately termed the default mode network, DMN) in which inverse correlations have been observed during resting state and event-related functional magnetic resonance imaging ...

Last Updated: 17 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Centrotemporal Epilepsy" returned 4 free, full-text review articles on human participants. First 3 results:

Transition issues for benign epilepsy with centrotemporal spikes, nonlesional focal epilepsy in otherwise normal children, childhood absence epilepsy, and juvenile myoclonic epilepsy.
 

Author(s): Carol S Camfield, Anne Berg, Ulrich Stephani, Elaine C Wirrell

Journal: Epilepsia. 2014 Aug;55 Suppl 3():16-20.

 

This chapter covers the syndromes of benign epilepsy with centrotemporal spikes (BECTS), nonlesional focal epilepsy in otherwise normal children (NLFN), and the genetic generalized epilepsies. BECTS is an epilepsy syndrome that always enters terminal remission before the general age ...

Last Updated: 11 Sep 2014

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Typical semiology of benign childhood epilepsy with centrotemporal spikes (BCECTS).
 

Author(s): U Stephani

Journal: Epileptic Disord. 2000 ;2 Suppl 1():S3-4.

 

The ILAE (1989) has defined benign childhood epilepsy with centro-temporal spikes (BCECTS) as follows: BCECTS is a syndrome of brief, simple, partial, hemifacial motor seizures, frequently having associated somatosensory symptoms which have a tendency to evolve into generalised tonic ...

Last Updated: 20 Mar 2001

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The electroencephalographic features of benign centrotemporal (rolandic) epilepsy of childhood.
 

Author(s): P Kellaway

Journal: Epilepsia. 2000 Aug;41(8):1053-6.

 

Last Updated: 5 Sep 2000

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Symptoms, Diagnosis, and Treatment

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