Celiac disease

Common Name(s)

Celiac disease, Celiac sprue

Celiac disease is an autoimmune disorder that damages the small intestine and inhibits absorption of nutrients. People with celiac disease cannot tolerate gluten, a protein in wheat, rye, barley, and in some products such as medicines, vitamins, and lip balms. When affected people eat food with gluten, or use a product with gluten, the immune system reacts by damaging tiny parts of the lining of the small intestine called villi. Because villi normally allow the blood to absorb nutrients from food, affected individuals become malnourished. Classic signs and symptoms are caused by inflammation of the gastrointestinal tract and may include diarrhea, weight loss, abdominal pain, swelling, and food intolerance. However, many people have other symptoms involving many body systems, and some people have no symptoms. While celiac disease tends to run in families, it does not follow a specific inheritance pattern. The risk to develop celiac disease is raised by having certain forms of the HLA-DQA1 and HLA-DQB1 genes. Treatment is a lifelong, gluten-free diet.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac disease" for support, advocacy or research.

Logo
Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

Last Updated: 10 Mar 2015

View Details
Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

Last Updated: 10 Mar 2015

View Details
Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

View Details
Logo
Celiac Disease Foundation

Celiac Disease Foundation drives diagnosis and treatment of celiac disease through advocacy, education, and advancing research to improve the quality of life for all people affected by gluten-related disorders.

Last Updated: 27 Mar 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac disease" for support, advocacy or research.

Logo
Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

http://www.coeliac.ie

Last Updated: 10 Mar 2015

View Details
Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

http://www.gluten.net

Last Updated: 10 Mar 2015

View Details
Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

View Details
Logo
Celiac Disease Foundation

Celiac Disease Foundation drives diagnosis and treatment of celiac disease through advocacy, education, and advancing research to improve the quality of life for all people affected by gluten-related disorders.

http://celiac.org

Last Updated: 27 Mar 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Celiac disease" returned 791 free, full-text research articles on human participants. First 3 results:

Risk of celiac disease according to HLA haplotype and country.
 

Author(s): Edwin Liu, Hye-Seung Lee, Daniel Agardh

Journal: N. Engl. J. Med.. 2014 Sep;371(11):1074.

 

Last Updated: 11 Sep 2014

Go To URL
Women with celiac disease present with fertility problems no more often than women in the general population.
 

Author(s): Nafeesa N Dhalwani, Joe West, Alyshah Abdul Sultan, Lu Ban, Laila J Tata

Journal: Gastroenterology. 2014 Dec;147(6):1267-74.e1; quiz e13-4.

 

Studies have associated infertility with celiac disease. However, these included small numbers of women attending infertility specialist services and subsequently screened for celiac disease, and therefore may not have been representative of the general population. We performed a ...

Last Updated: 3 Dec 2014

Go To URL
Celiac disease in an Ethiopian Jew.
 

Author(s): Z Ackerman, J Livovsky, D M Livovsky

Journal: Isr. Med. Assoc. J.. 2014 Jun;16(6):395-6.

 

Last Updated: 25 Jul 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Celiac disease" returned 117 free, full-text review articles on human participants. First 3 results:

Long term follow up of celiac disease-is atherosclerosis a problem?
 

Author(s): Anna Rybak, Bożena Cukrowska, Jerzy Socha, Piotr Socha

Journal:

 

Celiac disease (CD) is a lifelong condition and it often involves impaired nutrition, wide spectrum of symptoms and it requires constant dietetic treatment. The impact of the gluten-free diet on patients' nutritional status and on the other biochemical parameters is being widely investigated. ...

Last Updated: 23 Jul 2014

Go To URL
Risk of infertility in patients with celiac disease: a meta-analysis of observational studies.
 

Author(s): Juan Sebastian Lasa, Ignacio Zubiaurre, Luis Oscar Soifer

Journal: Arq Gastroenterol. ;51(2):144-50.

 

Celiac disease is an autoimmune disorder of the small intestine associated with several extra-intestinal features, such as reproductive disorders. The relationship between celiac disease and infertility has been previously assessed, with conflicting results.

Last Updated: 9 Jul 2014

Go To URL
Cereal-based gluten-free food: how to reconcile nutritional and technological properties of wheat proteins with safety for celiac disease patients.
 

Author(s): Carmela Lamacchia, Alessandra Camarca, Stefania Picascia, Aldo Di Luccia, Carmen Gianfrani

Journal:

 

The gluten-free diet is, to date, the only efficacious treatment for patients with Celiac Disease. In recent years, the impressive rise of Celiac Disease incidence, dramatically prompted changes in the dietary habit of an increasingly large population, with a rise in demand of gluten-free ...

Last Updated: 31 Jan 2014

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibody Treatment for Advanced Celiac Disease
 

Status: Recruiting

Condition Summary: Celiac Disease; Celiac Sprue; Gluten Enteropathy; Gluten-Sensitive Enteropathy

 

Last Updated: 13 May 2014

Go to URL
Celiac Disease and Unexplained Iron Deficiency in a Primary Care Setting
 

Status: Not yet recruiting

Condition Summary: Celiac Disease; Iron Deficiency; Iron Malabsorption

 

Last Updated: 13 Oct 2014

Go to URL
Screen-detected Coeliac Disease, a Population Based Study
 

Status: Recruiting

Condition Summary: Celiac Disease

 

Last Updated: 11 Dec 2014

Go to URL