Celiac Disease

Common Name(s)

Celiac Disease

Celiac disease is an autoimmune disorder that damages the small intestine and inhibits absorption of nutrients. People with celiac disease cannot tolerate gluten, a protein in wheat, rye, barley, and in some products such as medicines, vitamins, and lip balms. When affected people eat food with gluten, or use a product with gluten, the immune system reacts by damaging tiny parts of the lining of the small intestine called villi. Because villi normally allow the blood to absorb nutrients from food, affected individuals become malnourished. Classic signs and symptoms are caused by inflammation of the gastrointestinal tract and may include diarrhea, weight loss, abdominal pain, swelling, and food intolerance. However, many people have other symptoms involving many body systems, and some people have no symptoms. While celiac disease tends to run in families, it does not follow a specific inheritance pattern. The risk to develop celiac disease is raised by having certain forms of the HLA-DQA1 and HLA-DQB1 genes. Treatment is a lifelong, gluten-free diet.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2013

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Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

Last Updated: 15 Oct 2013

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Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

Last Updated: 24 Oct 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Celiac Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2013

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Coeliac Society of Ireland

The mission of the Coeliac Society of Ireland is to improve the quality of life for Coeliacs and those who benefit from a gluten free diet.

http://www.coeliac.ie

Last Updated: 15 Oct 2013

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Gluten Intolerance Group

The mission of the Gluten Intolerance Group of North America® is to support persons with gluten intolerances, celiac disease, dermatitis herpetiformis, and other gluten sensitivities, through consumer and industry services and programs that positively promote healthy lives.

http://www.gluten.net

Last Updated: 24 Oct 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Celiac Disease" returned 724 free, full-text research articles on human participants. First 3 results:

Images in clinical medicine. Occipital calcification and celiac disease.
 

Author(s): Rubens Gisbert Cury, Camila Hobi Moreira

Journal: N. Engl. J. Med.. 2014 Apr;370(16):e26.

 

Last Updated: 17 Apr 2014

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Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study.
 

Author(s): Joe West, Kate M Fleming, Laila J Tata, Timothy R Card, Colin J Crooks

Journal: Am. J. Gastroenterol.. 2014 May;109(5):757-68.

 

Few studies have quantified the incidence and prevalence of celiac disease (CD) and dermatitis herpetiformis (DH) nationally and regionally by time and age groups. Understanding this epidemiology is crucial for hypothesizing about causes and quantifying the burden of disease.

Last Updated: 6 May 2014

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Primary sclerosing cholangitis in patient with celiac disease complicated by cholecystic empyema and acute pancreatitis.
 

Author(s): P Piccolboni, E Ragone, A Inzirillo, R Utili

Journal: G Chir. ;34(9-10):267-70.

 

The association of celiac disease and sclerosing cholangitis is a well known, although unusual, pathologic feature of autoimmunity.

Last Updated: 17 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Celiac Disease" returned 109 free, full-text review articles on human participants. First 3 results:

[Genetic and epigenetic aspects of celiac disease].
 

Author(s): Dorottya Kocsis, Nóra Béres, Gábor Veres, Dolóresz Szabó, Katalin Eszter Müller, András Arató, Márk Juhász

Journal: Orv Hetil. 2014 Jan;155(3):83-8.

 

Genetic background of coeliac disease has been subjects to intensive research since decades. However, only results of HLA phenotyping have been taken over to routine clinical practice. Meanwhile, data on the role of epigenetical factors in the manifestation of diseases have been emerging. ...

Last Updated: 13 Jan 2014

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Endoscopic tools for the diagnosis and evaluation of celiac disease.
 

Author(s): Gianluca Ianiro, Antonio Gasbarrini, Giovanni Cammarota

Journal: World J. Gastroenterol.. 2013 Dec;19(46):8562-70.

 

Celiac disease (CD) is an autoimmune disease of the small bowel induced by ingestion of wheat, rye and barley. Current guidelines indicate histological analysis on at least four duodenal biopsies as the only way to diagnose CD. These indications are based on the conception of the ...

Last Updated: 31 Dec 2013

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Dermatitis herpetiformis, the celiac disease of the skin!
 

Author(s): Lorete Maria da Silva Kotze

Journal: Arq Gastroenterol. ;50(3):231-5.

 

Last Updated: 10 Dec 2013

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibody Treatment for Advanced Celiac Disease
 

Status: Recruiting

Condition Summary: Celiac Disease; Celiac Sprue; Gluten Enteropathy; Gluten-Sensitive Enteropathy

 

Last Updated: 13 May 2014

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Detection of Celiac Disease in Patients With Hypothyroidism
 

Status: Recruiting

Condition Summary: Celiac Disease; Hypothyroidism; Celiac Sprue; Malabsorption

 

Last Updated: 21 May 2013

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Celiac Disease and Diabetes- Dietary Intervention and Evaluation Trial
 

Status: Recruiting

Condition Summary: Celiac Disease; Diabetes Mellitus, Type 1

 

Last Updated: 6 Aug 2013

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