Catastrophic Antiphospholipid Syndrome

Common Name(s)

Catastrophic Antiphospholipid Syndrome

Catastrophic Antiphospholipid Syndrome is a disease that affects the small vessels, or tubes that carry blood, found in your body. Although the precise cause of this disorder is not fully understood, trauma, infection, and surgery have been identified as potential triggers of the condition. Catastrophic Antiphospholipid Syndrome can cause blockages in the vessels within the body, leading to symptoms such as chest and abdominal pain and bluish coloring of the skin (cyanosis). This condition is diagnosed based on blood tests (e.g. antibody levels and antiphospholipid antibody test). Treatments for Catastrophic Antiphosholipid Syndrome include the use of medications such as antibiotics, which fight infections, and anticoagulants, which work to preventing the formation of blockages in your vessels.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Catastrophic Antiphospholipid Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Catastrophic Antiphospholipid Syndrome" returned 43 free, full-text research articles on human participants. First 3 results:

Renal transplantation in a patient with catastrophic antiphospholipid syndrome and heparin-induced thrombocytopenia.
 

Author(s): Bezalel Podolak, Dorit Blickstein, Aida Inbal, Sigal Eizner, Ruth Rahamimov, Alexander Yussim, Eytan Mor

Journal: Isr. Med. Assoc. J.. 2014 Jan;16(1):61-2.

 

Last Updated: 28 Feb 2014

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Catastrophic antiphospholipid syndrome: a case series.
 

Author(s): Shachaf Shiber, Molad Yair

Journal: Isr. Med. Assoc. J.. 2013 Sep;15(9):481-4.

 

Antiphospholipid syndrome (APS) is an autoimmune disease with clinical manifestations of arterial and venous thrombosis, obstetric manifestations, and the presence of antiphospholipid antibodies or lupus anticoagulant. Catastrophic APS is a rare variant of APS, defined as acute failure ...

Last Updated: 13 Dec 2013

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Invasive aspergillosis masquerading as catastrophic antiphospholipid syndrome.
 

Author(s): Kathryn S Robinett, Bethany Weiler, Avelino C Verceles

Journal: Am. J. Crit. Care. 2013 Sep;22(5):448-51.

 

A 25-year-old woman with a history of systemic lupus erythematosus who was taking steroids came to the hospital because of vague signs and symptoms of weight loss, constipation, and oral ulcers. Multiorgan dysfunction developed, and catastrophic antiphospholipid syndrome was suspected. ...

Last Updated: 2 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Catastrophic Antiphospholipid Syndrome" returned 7 free, full-text review articles on human participants. First 3 results:

The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome.
 

Author(s): Cristina Rosário, Gisele Zandman-Goddard, Esther G Meyron-Holtz, David P D'Cruz, Yehuda Shoenfeld

Journal:

 

Over the last few years, accumulating data have implicated a role for ferritin as a signaling molecule and direct mediator of the immune system. Hyperferritinemia is associated with a multitude of clinical conditions and with worse prognosis in critically ill patients.

Last Updated: 23 Aug 2013

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Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases.
 

Author(s): José A Gómez-Puerta, Ricard Cervera, Gerard Espinosa, Ronald A Asherson, Mario García-Carrasco, Izaias P da Costa, Danieli C O Andrade, Eduardo F Borba, Alexander Makatsaria, Silvia Bucciarelli, Manuel Ramos-Casals, Josep Font

Journal: Ann. Rheum. Dis.. 2007 Jun;66(6):740-6.

 

The catastrophic variant of the antiphospholipid syndrome (APS) is a life-threatening form of presentation of this syndrome that can be triggered by several factors.

Last Updated: 21 May 2007

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[Catastrophic antiphospholipid syndrome: CAPS].
 

Author(s): Masahide Yamazaki

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2005 Dec;28(6):357-64.

 

Antiphospholipid syndrome (APS) is well known as an autoimmune thrombotic syndrome with recurrent thromboses. In APS, thromboses occurs both artery and vein, and from large to micro vessels. In contrast, so called catastrophic antiphospholipid syndrome, CAPS, develops multiple thromboses ...

Last Updated: 5 Jan 2006

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Antibody Syndrome; End Stage Renal Disease

 

Last Updated: 16 Aug 2011

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