Catastrophic Antiphospholipid Syndrome

Common Name(s)

Catastrophic Antiphospholipid Syndrome

Catastrophic Antiphospholipid Syndrome is a disease that affects the small vessels, or tubes that carry blood, found in your body. Although the precise cause of this disorder is not fully understood, trauma, infection, and surgery have been identified as potential triggers of the condition. Catastrophic Antiphospholipid Syndrome can cause blockages in the vessels within the body, leading to symptoms such as chest and abdominal pain and bluish coloring of the skin (cyanosis). This condition is diagnosed based on blood tests (e.g. antibody levels and antiphospholipid antibody test). Treatments for Catastrophic Antiphosholipid Syndrome include the use of medications such as antibiotics, which fight infections, and anticoagulants, which work to preventing the formation of blockages in your vessels.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Catastrophic Antiphospholipid Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Catastrophic Antiphospholipid Syndrome" returned 47 free, full-text research articles on human participants. First 3 results:

Catastrophic antiphospholipid syndrome: an orchestra with several musicians.
 

Author(s): Ignasi Rodríguez-Pintó, Alessandra Soriano, Gerard Espinosa, Yehuda Shoenfeld, Richard Cervera

Journal: Isr. Med. Assoc. J.. 2014 Sep;16(9):585-6.

 

Last Updated: 29 Oct 2014

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Malignancies: a possible "first hit" in the development of catastrophic antiphospholipid syndrome?
 

Author(s): Maria G Lazzaroni, Marco Taglietti, Angela Tincani

Journal: Isr. Med. Assoc. J.. 2014 Sep;16(9):583-4.

 

Last Updated: 29 Oct 2014

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Catastrophic antiphospholipid syndrome in cancer patients: an Interaction of clotting, autoimmunity and tumor growth?
 

Author(s): Ernesto De Meis, Biatriz C Brandão, Fernanda C Capella, José A P Garcia, Simone C Gregory

Journal: Isr. Med. Assoc. J.. 2014 Sep;16(9):544-7.

 

Thrombosis is a common phenomenon in patients with malignancies. It is believed that thrombosis is multifactorial and that in addition to mechanisms directly associated with cancer and its treatment, it may also be related to the interaction between the immune system and clotting. ...

Last Updated: 29 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Catastrophic Antiphospholipid Syndrome" returned 7 free, full-text review articles on human participants. First 3 results:

The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome.
 

Author(s): Cristina Rosário, Gisele Zandman-Goddard, Esther G Meyron-Holtz, David P D'Cruz, Yehuda Shoenfeld

Journal:

 

Over the last few years, accumulating data have implicated a role for ferritin as a signaling molecule and direct mediator of the immune system. Hyperferritinemia is associated with a multitude of clinical conditions and with worse prognosis in critically ill patients.

Last Updated: 23 Aug 2013

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Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases.
 

Author(s): José A Gómez-Puerta, Ricard Cervera, Gerard Espinosa, Ronald A Asherson, Mario García-Carrasco, Izaias P da Costa, Danieli C O Andrade, Eduardo F Borba, Alexander Makatsaria, Silvia Bucciarelli, Manuel Ramos-Casals, Josep Font

Journal: Ann. Rheum. Dis.. 2007 Jun;66(6):740-6.

 

The catastrophic variant of the antiphospholipid syndrome (APS) is a life-threatening form of presentation of this syndrome that can be triggered by several factors.

Last Updated: 21 May 2007

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[Catastrophic antiphospholipid syndrome: CAPS].
 

Author(s): Masahide Yamazaki

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2005 Dec;28(6):357-64.

 

Antiphospholipid syndrome (APS) is well known as an autoimmune thrombotic syndrome with recurrent thromboses. In APS, thromboses occurs both artery and vein, and from large to micro vessels. In contrast, so called catastrophic antiphospholipid syndrome, CAPS, develops multiple thromboses ...

Last Updated: 5 Jan 2006

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Antibody Syndrome; End Stage Renal Disease

 

Last Updated: 16 Aug 2011

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