Cataracts

Common Name(s)

Cataracts

Cataracts refer to the clouding of the lens of your eye. This commonly happens with age. The lens is a clear structure within the eye which people see through and that helps to focus light. Seeing with cataracts is much like seeing through a foggy window. Cataracts develop slowly, and may not cause serious problems at first. During this time, vision can be improved with better lighting and eyeglasses. However, cataracts may severely limit your ability to see over time. At this time, surgery may be required. Cataract surgery is generally regarded as a relatively safe and effective procedure.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cataracts" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cataracts" returned 337 free, full-text research articles on human participants. First 3 results:

A novel MIP gene mutation associated with autosomal dominant congenital cataracts in a Chinese family.
 

Author(s): Yibo Yu, Yinhui Yu, Peiqing Chen, Jinyu Li, Yanan Zhu, Yi Zhai, Ke Yao

Journal:

 

The major intrinsic protein gene (MIP), also known as MIP26 or AQP0, is a member of the water-transporting aquaporin family, which plays a critical role in the maintenance of lifelong lens transparency. To date, several mutations in MIP (OMIM 154050) have been linked to hereditary ...

Last Updated: 13 Jan 2014

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Inhibitory effect of r-hirudin variant III on streptozotocin-induced diabetic cataracts in rats.
 

Author(s): Xiaojian Gong, Qiuyan Zhang, Shuhua Tan

Journal:

 

The in vivo inhibitory effect of r-hirudin variant III (rHV3) on streptozotocin (STZ)-induced diabetic cataracts in rats was investigated. SD-rats were firstly made diabetic by a single intraperitoneal injection of 2% (W/V) STZ (65 mg/kg). Two weeks later, cataract formation was examined ...

Last Updated: 6 Jan 2014

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Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
 

Author(s): Ryan P Liegel, Mark T Handley, Adam Ronchetti, Stephen Brown, Lars Langemeyer, Andrea Linford, Bo Chang, Deborah J Morris-Rosendahl, Sarah Carpanini, Renata Posmyk, Verity Harthill, Eamonn Sheridan, Ghada M H Abdel-Salam, Paulien A Terhal, Francesca Faravelli, Patrizia Accorsi, Lucio Giordano, Lorenzo Pinelli, Britta Hartmann, Allison D Ebert, Francis A Barr, Irene A Aligianis, Duska J Sidjanin

Journal: Am. J. Hum. Genet.. 2013 Dec;93(6):1001-14.

 

blind sterile (bs) is a spontaneous autosomal-recessive mouse mutation discovered more than 30 years ago. Phenotypically, bs mice exhibit nuclear cataracts and male infertility; genetic analyses assigned the bs locus to mouse chromosome 2. In this study, we first positionally cloned ...

Last Updated: 9 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cataracts" returned 18 free, full-text review articles on human participants. First 3 results:

Surgery for cataracts in people with age-related macular degeneration.
 

Author(s): Heather Casparis, Kristina Lindsley, Irene C Kuo, Shameema Sikder, Neil B Bressler

Journal:

 

Cataract and age-related macular degeneration (AMD) are common causes of decreased vision that often occur simultaneously in people over age 50. Although cataract surgery is an effective treatment for cataract-induced visual loss, some clinicians suspect that such an intervention ...

Last Updated: 14 Jun 2012

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Prevention and management of cataracts in children with juvenile idiopathic arthritis-associated uveitis.
 

Author(s): Sheila Angeles-Han, Steven Yeh

Journal: Curr Rheumatol Rep. 2012 Apr;14(2):142-9.

 

Juvenile idiopathic arthritis (JIA)-associated uveitis can be associated with vision-compromising complications such as cataracts, glaucoma, synechiae, and band keratopathy. Of these, cataracts are one of the most common sequelae of JIA-associated uveitis and can result in significant ...

Last Updated: 9 Mar 2012

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Clinical and experimental advances in congenital and paediatric cataracts.
 

Author(s): Amanda Churchill, Jochen Graw

Journal: Philos. Trans. R. Soc. Lond., B, Biol. Sci.. 2011 Apr;366(1568):1234-49.

 

Cataracts (opacities of the lens) are frequent in the elderly, but rare in paediatric practice. Congenital cataracts (in industrialized countries) are mainly caused by mutations affecting lens development. Much of our knowledge about the underlying mechanisms of cataractogenesis has ...

Last Updated: 15 Mar 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
 

Status: Recruiting

Condition Summary: Unilateral Cataract Extraction; Congenital Cataract

 

Last Updated: 18 Jul 2014

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Clinical and Genetic Studies of Families With Congenital or Hereditary Cataracts
 

Status: Recruiting

Condition Summary: Cataract

 

Last Updated: 26 Apr 2014

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Cataract Removal and Alzheimer's Disease
 

Status: Recruiting

Condition Summary: Cataracts; Alzheimer's Disease

 

Last Updated: 3 Jun 2014

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