Carotid body tumor

Common Name(s)

Carotid body tumor

A carotid body tumor, also known as a chemodectoma or paraganglioma, is a tumor found in the upper neck where the two cartoid arteries branch off. There are three types of CBT's, sporadic, familial and hyperplastic. Sporadic CBTs are most common representing roughly 85% of all CBT cases. Familial CBTs are more common in younger children, and hyperplastic CBTs are typically found in people living in high altitude environments, such as New Mexico or Colorado. Carotid body tumors can be found in children, but the average age of onset is 45 years old. CBTs do not usually initially present with any symptoms other than being a physical mass on the neck. As the tumor grows and pushes against the carotid artery and surrounding nerves, other symptoms may occur, such as pain, a weak tongue or less ability to move the tongue, hoarseness, difficulty swallowing, and Horner syndrome (for more information see Horner syndrome.). Although most carotid body tumors are not fatal, some can be locally aggressive, so it is recommended that they are removed. Surgical removal of the tumor is sometimes followed by radiation therapy. Treatment for carotid body tumors is generally very safe, and outcomes are typically very successful.

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Condition Specific Organizations

Following organizations serve the condition "Carotid body tumor" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Carotid body tumor" returned 25 free, full-text research articles on human participants. First 3 results:

Carotid body tumor as a reversible cause of syncope.
 

Author(s): Paul Harlan Singh Janda, Venkatachalam Veerappan, Mark E McKenzie, Neel V Dhudshia

Journal: J Am Osteopath Assoc. 2011 Nov;111(11):638-44.

 

The causes of syncope are diverse and extensive; carotid body tumors are an extremely rare cause of syncope. These rare neoplasms represent less than 0.5% of all head and neck tumors. The authors present a case of a woman with syncope who was found to have a right-sided carotid body ...

Last Updated: 22 Nov 2011

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Significance of the preoperative guidance of dual-source CT in carotid body tumor.
 

Author(s): Yan Deng, Xi-ming Wang, Le-bin Wu, Cong Sun, Yan-hua Duan, Zhao-ping Cheng, Da-wei Wu

Journal: Chin. Med. J.. 2010 Oct;123(20):2816-9.

 

Accurate views of the head and neck vessels, tumor angiogenesis and the relationship of tumor and the surrounding blood vessels are especially crucial to carotid body tumor (CBT) patients. The aim of this study was to explore the value of dual-source CT (DSCT) cerebral and carotid ...

Last Updated: 1 Nov 2010

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Carotid body tumor presenting with carotid sinus syndrome.
 

Author(s): Américo Dinis da Gama, Gonçalo M Cabral

Journal: J. Vasc. Surg.. 2010 Dec;52(6):1668-70.

 

A healthy 46-year-old woman presented to our hospital with complaints of sudden and repeated episodes of syncope without accompanying signs or symptoms. Neurological investigation proved negative and a 24-hour Holter monitoring device revealed significant nocturnal cardiac pauses. ...

Last Updated: 14 Dec 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Carotid body tumor" returned 5 free, full-text review articles on human participants. First 3 results:

Case of spontaneous regression of carotid body tumor in a SDHD mutant: a discussion on potential mechanisms based on a review of the literature.
 

Author(s): Sebastiaan Hammer, Jeroen C Jansen, Eleonora P M van der Kleij-Corssmit, Frederik J Hes, Mark C Kruit

Journal:

 

Head and neck paragangliomas are tumors associated with the parasympathetic nerve system and typically show an indolent growth pattern. Therefore a conservative management strategy is considered in selected cases.

Last Updated: 19 Nov 2012

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A rare case of familial carotid body tumor in a patient with bilateral fibromuscular dysplasia.
 

Author(s): Daniel K Han, Eric W Fishman, Maggie H Walkup, Jeffrey W Olin, Michael L Marin, Peter L Faries

Journal: J. Vasc. Surg.. 2010 Sep;52(3):746-50.

 

Carotid body tumors (CBTs) are neuroendocrine tumors that arise due to mutations of respiratory cycle enzymes. Fibromuscular dysplasia (FMD) is a disease that causes narrowing of medium-sized arteries. There is no documented link between CBT and FMD. In this article, we report a case ...

Last Updated: 6 Sep 2010

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Paraganglioma: carotid body tumor.
 

Author(s): Jacqueline A Wieneke, Alice Smith

Journal: Head Neck Pathol. 2009 Dec;3(4):303-6.

 

Last Updated: 2 Jul 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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