Cardiomyopathy

Common Name(s)

Cardiomyopathy

Cardiomyopathy refers to group of conditions affecting the heart muscle, which cause the heart to become enlarged, thick and/or rigid. There are many different causes for cardiomyopathy including certain infections, exposure to toxic chemicals, and autoimmune conditions, where the body’s defense system actually attacks itself. As cardiomyopathy worsens, the heart muscle becomes weaker and is less able to pump blood through the body and maintain its rhythm. This can lead to heart failure, a condition where the heart tires out. Some may experience no symptoms and need no treatment, while, for others, cardiomyopathy may develop quickly with severe symptoms and serious complications. Typical symptoms of cardiomyopathy include breathlessness, swelling of the legs, bloating, cough, fatigue, dizziness and irregular heartbeats. A physician can diagnose cardiomyopathy using imaging tests, stress tests, blood tests or biopsy, where a needle is used to take out heart tissue to look at under a microscope. Treatment varies by type of cardiomyopathy, but commonly medications are used to manage symptoms. If the heart is badly damaged, certain more invasive procedures and surgeries may be needed to repair or replace the heart.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

Last Updated: 14 Jan 2015

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Cardiomyopathy Association

The Cardiomyopathy Association is a charity that provides information and support to families affected by the heart muscle disease cardiomyopathy. The charity helps families through cardiomyopathy support nurses, information days, support groups and a network of affected volunteers who provide support to others by telephone and email. It also has an extensive website (www.cardiomyopathy.org) with details about the condition, treatments, living with the disease, and latest research.

Last Updated: 15 Mar 2013

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Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

Last Updated: 20 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

https://www.barthsyndrome.org

Last Updated: 14 Jan 2015

View Details
Cardiomyopathy Association

The Cardiomyopathy Association is a charity that provides information and support to families affected by the heart muscle disease cardiomyopathy. The charity helps families through cardiomyopathy support nurses, information days, support groups and a network of affected volunteers who provide support to others by telephone and email. It also has an extensive website (www.cardiomyopathy.org) with details about the condition, treatments, living with the disease, and latest research.

http://www.cardiomyopathy.org

Last Updated: 15 Mar 2013

View Details
Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

http://www.childrenscardiomyopathy.org

Last Updated: 20 May 2014

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General Support Organizations

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General Resources

CCF General Brochure

This brochure is an introduction to the Children's Cardiomyopathy Foundation, including a brief history of the organization and descriptions of the foundation's work.

Updated 18 Oct 2012

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CCF Educational Materials

A link to the various educational materials CCF offers for families and professionals.

Updated 18 Oct 2012

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CCF Patient Resource Overview

An overview of the patient resources CCF has to offer.

Updated 22 Oct 2012

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CCF Awarded Research Grants

A description of the types of projects CCF funds to promote scientific knowledge related to the treatment and cure of pediatric cardiomyopathy.

Updated 22 Oct 2012

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CCF Research Grant Program Overview.

CCF Research Grant Program Overview.

Updated 22 Oct 2012

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Barth Syndrome Professional Healthcare Brochure

Important information regarding diagnosis and treatment of Barth syndrome.

Updated 12 Apr 2014

Open Doc
2014 Conference Program

2014 Conference Program

Updated 14 Jan 2015

Open Doc
How to Diagnose

How to diagnose Barth syndrome

Updated 14 Jan 2015

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Overview of Barth syndrome

Overview of Barth syndrome

Updated 14 Jan 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cardiomyopathy" returned 4705 free, full-text research articles on human participants. First 3 results:

Reverse remodeling in dilated cardiomyopathy: dream come true?
 

Author(s): Shemy Carasso, Offer Amir

Journal: Isr. Med. Assoc. J.. 2014 Jul;16(7):444-5.

 

Last Updated: 29 Aug 2014

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Prevalence and clinical predictors of reverse remodeling in patients with dilated cardiomyopathy.
 

Author(s): Michael Arad, Tamar Nussbaum, Ido Blechman, Micha S Feinberg, Nira Koren-Morag, Yael Peled, Dov Freimark

Journal: Isr. Med. Assoc. J.. 2014 Jul;16(7):405-11.

 

Contemporary therapiesimprove prognosis and may restore left ventricular (LV) sizeand function.

Last Updated: 29 Aug 2014

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Quantifying late gadolinium enhancement on CMR provides additional prognostic information in early risk-stratification of nonischemic cardiomyopathy: a cohort study.
 

Author(s): Pauli Pöyhönen, Sari Kivistö, Miia Holmström, Helena Hänninen

Journal:

 

Suspected nonischemic cardiomyopathy (NICM) is a common clinical setting with highly variable prognosis. Early noninvasive risk-stratification is important for justification of invasive examinations, specific treatment and patient surveillance. We studied the additional prognostic ...

Last Updated: 1 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cardiomyopathy" returned 427 free, full-text review articles on human participants. First 3 results:

Gemcitabine-induced cardiomyopathy: a case report and review of the literature.
 

Author(s): Muhammad F Khan, Silvija Gottesman, Ravichandra Boyella, Elizabeth Juneman

Journal:

 

Newly developed antineoplastic drugs have resulted in improvements in morbidity and mortality from many forms of cancers. However, some of these new chemotherapeutic agents have potentially lethal side effects, which are now being exposed with their widespread use. Gemcitabine is ...

Last Updated: 9 Jul 2014

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Arrhythmogenic right ventricular cardiomyopathy in pregnancy.
 

Author(s): Aysen Agir, Serdar Bozyel, Umut Celikyurt, Onur Argan, Irem Yilmaz, Kurtulus Karauzum, Ahmet Vural

Journal: Int Heart J. 2014 ;55(4):372-6.

 

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is predominantly a genetically determined heart muscle disorder that is characterized by fibro-fatty replacement of the right ventricular (RV) myocardium.(1)) The clinical spectrum of ARVC may represent from asymptomatic premature ...

Last Updated: 10 Jul 2014

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Proteomic profiling of the dystrophin-deficient mdx phenocopy of dystrophinopathy-associated cardiomyopathy.
 

Author(s): Ashling Holland, Kay Ohlendieck

Journal: Biomed Res Int. 2014 ;2014():246195.

 

Cardiorespiratory complications are frequent symptoms of Duchenne muscular dystrophy, a neuromuscular disorder caused by primary abnormalities in the dystrophin gene. Loss of cardiac dystrophin initially leads to changes in dystrophin-associated glycoproteins and subsequently triggers ...

Last Updated: 28 Apr 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC)
 

Status: Recruiting

Condition Summary: Dilated Cardiomyopathy (DCM); Ischemic Cardiomyopathy; Nonischemic Cardiomyopathy; Heart Failure

 

Last Updated: 20 Jan 2015

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Registry and Survey of Women With Pregnancy Related Cardiomyopathy
 

Status: Recruiting

Condition Summary: Cardiomyopathy; Pregnancy-Associated Cardiomyopathy; Heart Failure

 

Last Updated: 25 May 2006

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Virtual LV Lead Navigation in Patients With Ischemic Cardiomyopathy
 

Status: Recruiting

Condition Summary: Cardiomyopathy; Ischemic Cardiomyopathy

 

Last Updated: 10 Dec 2013

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