Cardiomyopathy

Common Name(s)

Cardiomyopathy

Cardiomyopathy refers to group of conditions affecting the heart muscle, which cause the heart to become enlarged, thick and/or rigid. There are many different causes for cardiomyopathy including certain infections, exposure to toxic chemicals, and autoimmune conditions, where the body’s defense system actually attacks itself. As cardiomyopathy worsens, the heart muscle becomes weaker and is less able to pump blood through the body and maintain its rhythm. This can lead to heart failure, a condition where the heart tires out. Some may experience no symptoms and need no treatment, while, for others, cardiomyopathy may develop quickly with severe symptoms and serious complications. Typical symptoms of cardiomyopathy include breathlessness, swelling of the legs, bloating, cough, fatigue, dizziness and irregular heartbeats. A physician can diagnose cardiomyopathy using imaging tests, stress tests, blood tests or biopsy, where a needle is used to take out heart tissue to look at under a microscope. Treatment varies by type of cardiomyopathy, but commonly medications are used to manage symptoms. If the heart is badly damaged, certain more invasive procedures and surgeries may be needed to repair or replace the heart.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

Last Updated: 11 Apr 2016

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Cardiomyopathy Association

The Cardiomyopathy Association is a charity that provides information and support to families affected by the heart muscle disease cardiomyopathy. The charity helps families through cardiomyopathy support nurses, information days, support groups and a network of affected volunteers who provide support to others by telephone and email. It also has an extensive website (www.cardiomyopathy.org) with details about the condition, treatments, living with the disease, and latest research.

Last Updated: 15 Mar 2013

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Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

Last Updated: 20 Jul 2015

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Team Titin

Team Titin is making a worldwide difference in Titin related muscle and heart disorders by: collaborating with other organizations, raising awareness, providing education, and supporting research. Our goal is to serve as a catalyst for researchers and clinicians to develop a better understanding of Titin related disorders leading ultimately to a cure.

Last Updated: 23 May 2016

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

https://www.barthsyndrome.org

Last Updated: 11 Apr 2016

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Cardiomyopathy Association

The Cardiomyopathy Association is a charity that provides information and support to families affected by the heart muscle disease cardiomyopathy. The charity helps families through cardiomyopathy support nurses, information days, support groups and a network of affected volunteers who provide support to others by telephone and email. It also has an extensive website (www.cardiomyopathy.org) with details about the condition, treatments, living with the disease, and latest research.

http://www.cardiomyopathy.org

Last Updated: 15 Mar 2013

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Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

http://www.childrenscardiomyopathy.org

Last Updated: 20 Jul 2015

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Team Titin

Team Titin is making a worldwide difference in Titin related muscle and heart disorders by: collaborating with other organizations, raising awareness, providing education, and supporting research. Our goal is to serve as a catalyst for researchers and clinicians to develop a better understanding of Titin related disorders leading ultimately to a cure.

http://titinmyopathy.com/

Last Updated: 23 May 2016

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General Resources

CCF General Brochure

This brochure is an introduction to the Children's Cardiomyopathy Foundation, including a brief history of the organization and descriptions of the foundation's work.

Updated 18 Oct 2012

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CCF Educational Materials

A link to the various educational materials CCF offers for families and professionals.

Updated 18 Oct 2012

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CCF Patient Resource Overview

An overview of the patient resources CCF has to offer.

Updated 22 Oct 2012

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CCF Awarded Research Grants

A description of the types of projects CCF funds to promote scientific knowledge related to the treatment and cure of pediatric cardiomyopathy.

Updated 22 Oct 2012

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CCF Research Grant Program Overview.

CCF Research Grant Program Overview.

Updated 22 Oct 2012

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Barth Syndrome Professional Healthcare Brochure

Important information regarding diagnosis and treatment of Barth syndrome.

Updated 12 Apr 2014

Open Doc
2014 Conference Program

2014 Conference Program

Updated 14 Jan 2015

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How to Diagnose

How to diagnose Barth syndrome

Updated 14 Jan 2015

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Overview of Barth syndrome

Overview of Barth syndrome

Updated 14 Jan 2015

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Barath Syndrome Journal

Newsletter published twice a year.

Updated 15 Mar 2016

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cardiomyopathy" returned 5942 free, full-text research articles on human participants. First 3 results:

Prognostic Impact of Segmental Wall Motion Abnormality in Patients With Idiopathic Dilated Cardiomyopathy.
 

Author(s): Yuichiro Iida, Takayuki Inomata, Toyoji Kaida, Teppei Fujita, Yuki Ikeda, Takeru Nabeta, Shunsuke Ishii, Toshimi Koitabashi, Ichiro Takeuchi, Junya Ako

Journal: Int Heart J. 2017 Aug;58(4):544-550.

 

The clinical impact of left ventricular (LV) segmental wall motion abnormalities (SWMA) in patients with idiopathic dilated cardiomyopathy (IDCM) has not been well elucidated.Among 100 consecutive IDCM patients with follow-up visits, we enrolled 85 after excluding those with left ...

Last Updated: 13 Jul 2017

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Prevalence and Spectrum of NKX2-5 Mutations Associated With Sporadic Adult-Onset Dilated Cardiomyopathy.
 

Author(s): Jia-Hong Xu, Jian-Yun Gu, Yu-Han Guo, Hong Zhang, Xing-Biao Qiu, Ruo-Gu Li, Hong-Yu Shi, Hua Liu, Xiao-Xiao Yang, Ying-Jia Xu, Xin-Kai Qu, Yi-Qing Yang

Journal: Int Heart J. 2017 Aug;58(4):521-529.

 

Dilated cardiomyopathy (DCM), the most common form of primary myocardial disease, is a leading cause of congestive heart failure and the most common indication for heart transplantation. Recently, NKX2-5 mutations have been involved in the pathogenesis of familial DCM. However, the ...

Last Updated: 10 Jul 2017

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Echocardiography and Electrocardiography Variables Correlate With the New York Heart Association classification: An Observational Study of Ischemic Cardiomyopathy Patients.
 

Author(s): Ying Hu, Shifeng Jiang, Siyuan Lu, Rong Xu, Yunping Huang, Zongliang Zhao, Yi Qu

Journal: Medicine (Baltimore). 2017 Jun;96(26):e7071.

 

The aim of our study was to determine whether combinations of ultrasound echocardiography (UCG) and electrocardiography (EKG) parameters correlated with the functional status of ischemic cardiomyopathy (ICM) patients according to the New York Heart Association (NYHA) classification ...

Last Updated: 28 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cardiomyopathy" returned 573 free, full-text review articles on human participants. First 3 results:

Anesthetic management of patients with dilated cardiomyopathy for noncardiac surgery.
 

Author(s): C-Q Chen, X Wang, J Zhang, S-M Zhu

Journal: Eur Rev Med Pharmacol Sci. 2017 Feb;21(3):627-634.

 

Anesthetic management of patients with dilated cardiomyopathy (DCM) is a challenge to the anesthesiologist, due to poor left systolic function, ventricular enlargement, risk of malignant arrhythmias and sudden cardiac death. Therefore, preoperative assessment and appropriate anesthetic ...

Last Updated: 27 Feb 2017

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Genetics and genomics of dilated cardiomyopathy and systolic heart failure.
 

Author(s): Upasana Tayal, Sanjay Prasad, Stuart A Cook

Journal:

 

Heart failure is a major health burden, affecting 40 million people globally. One of the main causes of systolic heart failure is dilated cardiomyopathy (DCM), the leading global indication for heart transplantation. Our understanding of the genetic basis of both DCM and systolic ...

Last Updated: 23 Feb 2017

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Cell Therapies in Cardiomyopathy: Current Status of Clinical Trials.
 

Author(s): Ming Hao, Richard Wang, Wen Wang

Journal: Anal Cell Pathol (Amst). 2017 ;2017():9404057.

 

Because the human heart has limited potential for regeneration, the loss of cardiomyocytes during cardiac myopathy and ischaemic injury can result in heart failure and death. Stem cell therapy has emerged as a promising strategy for the treatment of dead myocardium, directly or indirectly, ...

Last Updated: 14 Feb 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 29 Jun 2017

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A Clinical Study of Immunoadsorption Therapy for Dilated Cardiomyopathy
 

Status: Recruiting

Condition Summary: Dilated Cardiomyopathy

 

Last Updated: 8 Oct 2016

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Cardiomyopathy Arrhythmia Risk Evaluation
 

Status: Recruiting

Condition Summary: Cardiomyopathy

 

Last Updated: 24 May 2016

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