Cardiomyopathy

Common Name(s)

Cardiomyopathy

Cardiomyopathy refers to group of conditions affecting the heart muscle, which cause the heart to become enlarged, thick and/or rigid. There are many different causes for cardiomyopathy including certain infections, exposure to toxic chemicals, and autoimmune conditions, where the body’s defense system actually attacks itself. As cardiomyopathy worsens, the heart muscle becomes weaker and is less able to pump blood through the body and maintain its rhythm. This can lead to heart failure, a condition where the heart tires out. Some may experience no symptoms and need no treatment, while, for others, cardiomyopathy may develop quickly with severe symptoms and serious complications. Typical symptoms of cardiomyopathy include breathlessness, swelling of the legs, bloating, cough, fatigue, dizziness and irregular heartbeats. A physician can diagnose cardiomyopathy using imaging tests, stress tests, blood tests or biopsy, where a needle is used to take out heart tissue to look at under a microscope. Treatment varies by type of cardiomyopathy, but commonly medications are used to manage symptoms. If the heart is badly damaged, certain more invasive procedures and surgeries may be needed to repair or replace the heart.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

Last Updated: 11 Apr 2016

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Cardiomyopathy Association

The Cardiomyopathy Association is a charity that provides information and support to families affected by the heart muscle disease cardiomyopathy. The charity helps families through cardiomyopathy support nurses, information days, support groups and a network of affected volunteers who provide support to others by telephone and email. It also has an extensive website (www.cardiomyopathy.org) with details about the condition, treatments, living with the disease, and latest research.

Last Updated: 15 Mar 2013

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Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

Last Updated: 20 Jul 2015

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Team Titin

Team Titin is making a worldwide difference in Titin related muscle and heart disorders by: collaborating with other organizations, raising awareness, providing education, and supporting research. Our goal is to serve as a catalyst for researchers and clinicians to develop a better understanding of Titin related disorders leading ultimately to a cure.

Last Updated: 23 May 2016

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cardiomyopathy" for support, advocacy or research.

Barth Syndrome Foundation

Our mission is saving lives through education, advances in treatment, and finding a cure for Barth syndrome.

https://www.barthsyndrome.org

Last Updated: 11 Apr 2016

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Cardiomyopathy Association

The Cardiomyopathy Association is a charity that provides information and support to families affected by the heart muscle disease cardiomyopathy. The charity helps families through cardiomyopathy support nurses, information days, support groups and a network of affected volunteers who provide support to others by telephone and email. It also has an extensive website (www.cardiomyopathy.org) with details about the condition, treatments, living with the disease, and latest research.

http://www.cardiomyopathy.org

Last Updated: 15 Mar 2013

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Children's Cardiomyopathy Foundation

Our mission is to accelerate the search for a cure by stimulating and supporting promising research on pediatric cardiomyopathy, by educating and assisting physicians and patients on the complexities of the disease, and by increasing awareness and advocacy on behalf of affected children and their families.

http://www.childrenscardiomyopathy.org

Last Updated: 20 Jul 2015

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Team Titin

Team Titin is making a worldwide difference in Titin related muscle and heart disorders by: collaborating with other organizations, raising awareness, providing education, and supporting research. Our goal is to serve as a catalyst for researchers and clinicians to develop a better understanding of Titin related disorders leading ultimately to a cure.

http://titinmyopathy.com/

Last Updated: 23 May 2016

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General Resources

CCF General Brochure

This brochure is an introduction to the Children's Cardiomyopathy Foundation, including a brief history of the organization and descriptions of the foundation's work.

Updated 18 Oct 2012

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CCF Educational Materials

A link to the various educational materials CCF offers for families and professionals.

Updated 18 Oct 2012

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CCF Patient Resource Overview

An overview of the patient resources CCF has to offer.

Updated 22 Oct 2012

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CCF Awarded Research Grants

A description of the types of projects CCF funds to promote scientific knowledge related to the treatment and cure of pediatric cardiomyopathy.

Updated 22 Oct 2012

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CCF Research Grant Program Overview.

CCF Research Grant Program Overview.

Updated 22 Oct 2012

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Barth Syndrome Professional Healthcare Brochure

Important information regarding diagnosis and treatment of Barth syndrome.

Updated 12 Apr 2014

Open Doc
2014 Conference Program

2014 Conference Program

Updated 14 Jan 2015

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How to Diagnose

How to diagnose Barth syndrome

Updated 14 Jan 2015

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Overview of Barth syndrome

Overview of Barth syndrome

Updated 14 Jan 2015

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Barath Syndrome Journal

Newsletter published twice a year.

Updated 15 Mar 2016

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cardiomyopathy" returned 5901 free, full-text research articles on human participants. First 3 results:

Arrhythmogenic Right Ventricular Cardiomyopathy.
 

Author(s): Domenico Corrado, Mark S Link, Hugh Calkins

Journal: N. Engl. J. Med.. 2017 04;376(15):1489-90.

 

Last Updated: 13 Apr 2017

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The Histological Features of a Myocardial Biopsy Specimen in a Patient in the Acute Phase of Reversible Catecholamine-induced Cardiomyopathy due to Pheochromocytoma.
 

Author(s): Miyuki Miura, Hiroaki Kawano, Takeo Yoshida, Yuki Yamagata, Tomoo Nakata, Seiji Koga, Satoshi Ikeda, Kan Kageyama, Kuniko Abe, Koji Maemura

Journal: Intern. Med.. 2017 ;56(6):665-671.

 

A 63-year-old Japanese woman with an adrenal tumor was transferred to our hospital due to cardiogenic shock. Right and left ventriculography showed severe hypokinesis of the middle segment and the apex in both ventricles, and an endomyocardial biopsy demonstrated a small number of ...

Last Updated: 21 Mar 2017

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Genetic anticipation in a special form of hypertrophic cardiomyopathy with sudden cardiac death in a family with 74 members across 5 generations.
 

Author(s): Xiying Guo, Chaomei Fan, Yanping Wang, Miao Wang, Chi Cai, Yinjian Yang, Shihua Zhao, Fujian Duan, Yishi Li

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6249.

 

Hypertrophic cardiomyopathy (HCM) is the most common heritable heart disease. The genetic anticipation of HCM and its associated etiology, sudden cardiac death (SCD), remains unclear. The aim of this study was to investigate the mechanism underlying the genetic anticipation of HCM ...

Last Updated: 15 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cardiomyopathy" returned 563 free, full-text review articles on human participants. First 3 results:

Cell Therapies in Cardiomyopathy: Current Status of Clinical Trials.
 

Author(s): Ming Hao, Richard Wang, Wen Wang

Journal: Anal Cell Pathol (Amst). 2017 ;2017():9404057.

 

Because the human heart has limited potential for regeneration, the loss of cardiomyocytes during cardiac myopathy and ischaemic injury can result in heart failure and death. Stem cell therapy has emerged as a promising strategy for the treatment of dead myocardium, directly or indirectly, ...

Last Updated: 14 Feb 2017

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From molecular mechanism to morphological changes in cardiomyopathy.
 

Author(s): Cristina Florescu, Ion Rogoveanu, Cristin Constantin Vere, Georgică Costinel Târtea, Elena Anca Târtea, LaurenŢiu Mogoantă

Journal: Rom J Morphol Embryol. 2016 ;57(4):1207-1214.

 

The aim of this study is to make a foray in the world of constitutive elements of the architectural and functional organizing of the cardiomyocytes involved in cardiomyopathies and of the genetic molecules that they express. Primary cardiomyopathies represent a group of diseases characterized ...

Last Updated: 8 Feb 2017

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[Peripartum cardiomyopathy: about a case and review of the literature].
 

Author(s): Abdelmajid Bouzerda

Journal:

 

Peripartum cardiomyopathy or primitive pregnancy-induced cardiomyopathy is a rare and little known entity characterized systolic heart failure occurring in the last month of pregnancy or in the first five months postpartum in the absence of known cause or pre-existing heart disease. ...

Last Updated: 3 Feb 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 25 Aug 2016

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A Clinical Study of Immunoadsorption Therapy for Dilated Cardiomyopathy
 

Status: Recruiting

Condition Summary: Dilated Cardiomyopathy

 

Last Updated: 8 Oct 2016

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Cardiomyopathy Arrhythmia Risk Evaluation
 

Status: Recruiting

Condition Summary: Cardiomyopathy

 

Last Updated: 24 May 2016

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