Caffey Disease

Common Name(s)

Caffey Disease

Caffey disease is a bone disorder that most often occurs in babies. It is characterized by the excessive formation of new bone (hyperostosis) in the jaw, shoulder blades, collarbones, and shafts of long bones in the arms and legs. Affected bones may double or triple in width. In some cases, two bones that are next to each other may become fused. Caffey disease is caused by a mutation in the COL1A1 gene. It is inherited in an autosomal dominant pattern, but not all people who inherit the mutation develop signs and symptoms. This is due to incomplete penetrance.  
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Caffey Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Caffey Disease" returned 6 free, full-text research articles on human participants. First 3 results:

[Neonatal cortical hyperostosis (Caffey disease)].
 

Author(s): A de Blas, M Martín-Frías, M Toledano, M Gomez, J Corbatón, R Yturriaga

Journal: An Pediatr (Barc). 2013 Sep;79(3):189-90.

 

Last Updated: 26 Aug 2013

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Prenatal Caffey disease.
 

Author(s): Ori Hochwald, Horacio Osiovich

Journal: Isr. Med. Assoc. J.. 2011 Feb;13(2):113-4.

 

Last Updated: 29 Mar 2011

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Infantile cortical hyperostosis (Caffey disease): a possible misdiagnosis as physical abuse.
 

Author(s): Henny P W Lo, H Y Lau, C H Li, K T So

Journal: Hong Kong Med J. 2010 Oct;16(5):397-9.

 

Infantile cortical hyperostosis (Caffey disease) is a rare self-limiting inflammatory bony disease of early infancy. We report a 1-month-old Chinese boy with Caffey disease who presented with painful swelling over his shins bilaterally. Physical abuse was initially suspected, but ...

Last Updated: 4 Oct 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Caffey Disease" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.