Buschke Ollendorff Syndrome

Common Name(s)

Buschke Ollendorff Syndrome

Buschke Ollendorff syndrome (BOS) is a rare, hereditary disorder of the connective tissue. It is mainly characterized by benign, connective tissue nevi (also called hamartomas) in the skin, as well as osteopoikilosis ('spotted bones' caused by small, round spots of increased bone density). In some individuals both the skin and bone are affected, while others may lack skin or bone manifestations. Some affected individuals have joint pain. Symptoms may begin at any age. BOS is caused by mutations in the LEMD3 gene and is inherited in an autosomal dominant manner. Surgery to remove skin lesions is sometimes done for cosmetic reasons and in some patients, surgical treatment of deafness is possible.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Buschke Ollendorff Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Buschke Ollendorff Syndrome" returned 1 free, full-text research articles on human participants. First 3 results:

Buschke-Ollendorff syndrome accidentally diagnosed after a left ankle sprain.
 

Author(s): P Lygdas, E G Ballas, I P Stathopoulos, T Theologis, K Pistevos, D Pasparakis

Journal: J Musculoskelet Neuronal Interact. 2014 Mar;14(1):144-7.

 

Last Updated: 3 Mar 2014

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Reviews from the PubMed Database

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The terms "Buschke Ollendorff Syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.