Buruli Ulcer

Common Name(s)

Buruli Ulcer

Buruli ulcer is a tropical disease caused by an infection from the Mycobacterium ulcerans, a bacterium which belongs to the same family of bacteria that causes tuberculosis and leprosy. Most cases of buruli ulcer occur in tropical and subtropical regions, and has been reported in 33 countries in Africa, the Americas, Asia and the Western Pacific. The exact way that the disease is transmitted is unknown, though it is thought that living agents, such as aquatic insects or mosquitoes may play some role. Buruli ulcer usually begins with a painless swelling or a large painless area in the skin. Without treatment, however, the area will form a large ulcer within four weeks, and can sometimes result in permanent disfigurement and disability. When Buruli ulcer is detected early, it can be cured with a combination of antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Buruli Ulcer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Buruli Ulcer" returned 145 free, full-text research articles on human participants. First 3 results:

Wound care in Buruli ulcer disease in Ghana and Benin.
 

Author(s): Kristien Velding, Sandor-Adrian Klis, Kabiru M Abass, Wilson Tuah, Ymkje Stienstra, Tjip van der Werf

Journal: Am. J. Trop. Med. Hyg.. 2014 Aug;91(2):313-8.

 

Buruli ulcer (BU) is a disease affecting the skin, subcutaneous fat, and bone tissues. Wound care is important in the prevention of disabilities. Awareness of current wound care practices in BU-endemic regions is necessary for future wound care interventions. Thirty-one health care ...

Last Updated: 7 Aug 2014

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Potential wildlife sentinels for monitoring the endemic spread of human buruli ulcer in South-East australia.
 

Author(s): Connor Carson, Caroline J Lavender, Kathrine A Handasyde, Carolyn R O'Brien, Nick Hewitt, Paul D R Johnson, Janet A M Fyfe

Journal:

 

The last 20 years has seen a significant series of outbreaks of Buruli/Bairnsdale Ulcer (BU), caused by Mycobacterium ulcerans, in temperate south-eastern Australia (state of Victoria). Here, the prevailing view of M. ulcerans as an aquatic pathogen has been questioned by recent research ...

Last Updated: 5 Feb 2014

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Burden of Mycobacterium ulcerans disease (Buruli ulcer) and the underreporting ratio in the territory of Songololo, Democratic Republic of Congo.
 

Author(s): Delphin Mavinga Phanzu, Patrick Suykerbuyk, Paul Saunderson, Philippe Ngwala Lukanu, Jean-Bedel Masamba Minuku, Désiré Bofunga B Imposo, Blanchard Mbadu Diengidi, Makanzu Kayinua, Jean-Jacques Tamfum Muyembe, Pascal Tshindele Lutumba, Bouke C de Jong, Françoise Portaels, Marleen Boelaert

Journal:

 

Cutaneous infection by Mycobacterium ulcerans, also known as Buruli ulcer (BU), represents the third most common mycobacterial disease in the world after tuberculosis and leprosy. Data on the burden of BU disease in the Democratic Republic of Congo are scanty. This study aimed to ...

Last Updated: 16 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Buruli Ulcer" returned 6 free, full-text review articles on human participants. First 3 results:

The impact of community health workers (CHWs) on Buruli ulcer in sub-Saharan Africa: a systematic review.
 

Author(s): Marius Zambou Vouking, Violette Claire Tamo, Lawrence Mbuagbaw

Journal:

 

Buruli ulcer (BU) is a cutaneous neglected tropical disease caused by Mycobacterium ulcerans. Participation of Community Health Workers (CHWs) is an integral part of the management of BU, yet their impact has not been systematically evaluated in sub-Saharan Africa.

Last Updated: 6 Sep 2013

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Buruli ulcer and mycolactone-producing mycobacteria.
 

Author(s): Kazue Nakanaga, Rie Roselyne Yotsu, Yoshihiko Hoshino, Koichi Suzuki, Masahiko Makino, Norihisa Ishii

Journal: Jpn. J. Infect. Dis.. 2013 ;66(2):83-8.

 

Buruli ulcer (BU) is an emerging human disease caused by Mycobacterium ulcerans, which mainly affects the extremities. It is most endemic in sub-Saharan Africa; however, it has been reported worldwide, including in some non-tropical areas. "M. ulcerans subsp. shinshuense" is proposed ...

Last Updated: 21 Mar 2013

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Buruli ulcer.
 

Author(s): Thorbjorg Einarsdottir, Kris Huygen

Journal: Hum Vaccin. 2011 Nov;7(11):1198-203.

 

Buruli Ulcer (BU) is a neglected, necrotizing skin disease, caused by M. ulcerans, that can leave patients with prominent scars and lifelong disability. M. ulcerans produces a diffusible lipid toxin, mycolactone, essential for bacterial virulence. Prevention is difficult as little ...

Last Updated: 29 Dec 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pathogenesis and Management of M. Ulcerans Disease, Buruli Ulcer
 

Status: Recruiting

Condition Summary: Buruli Ulcer; Mycobacterium Ulcerans Disease

 

Last Updated: 31 May 2014

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Timing of Surgical Intervention in Buruli Ulcer Patients Treated With Antibiotics
 

Status: Recruiting

Condition Summary: Mycobacterium Ulcerans Disease; Buruli Ulcer

 

Last Updated: 13 Jul 2012

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WHO Drug Study for Buruli Ulcer - Comparison of SR8 and CR8
 

Status: Recruiting

Condition Summary: Mycobacterium Ulcerans Infection

 

Last Updated: 4 Aug 2013

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