Familial idiopathic basal ganglia calcification

Common Name(s)

Familial idiopathic basal ganglia calcification

Familial idiopathic basal ganglia calcification (FIBGC) is a neurodegenerative disorder characterized by calcium deposits in the basal ganglia, a part of the brain that helps start and control movement. The first symptoms often include clumsiness, fatigue, unsteady walking, slow or slurred speech, difficulty swallowing, and dementia. Seizures of various types frequently occur. Symptoms typically start in an individual's 20's to 40's but may begin at any age. The neuropsychiatric symptoms and movement disorders worsen over time. Mutations in the SLC20A2 and PDGFRB genes have been found to cause FIBGC, and this condition is inherited in an autosomal dominant manner.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial idiopathic basal ganglia calcification" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial idiopathic basal ganglia calcification" returned 4 free, full-text research articles on human participants. First 3 results:

Association between a novel mutation in SLC20A2 and familial idiopathic basal ganglia calcification.
 

Author(s): Yang Zhang, Xianan Guo, Anhua Wu

Journal: PLoS ONE. 2013 ;8(2):e57060.

 

Familial idiopathic basal ganglia calcification (FIBGC) is a rare, autosomal dominant disorder involving bilateral calcification of the basal ganglia. To identify gene mutations related to a Chinese FIBGC lineage, we evaluated available individuals in the family using CT scans. DNA ...

Last Updated: 25 Feb 2013

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Anticipation of familial idiopathic basal ganglia calcification?
 

Author(s): Kengo Maeda, Ryo Idehara, Hiroko Nakamura, Akinori Hirai

Journal: Intern. Med.. 2012 ;51(8):987.

 

Last Updated: 16 Apr 2012

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Familial idiopathic basal ganglia calcification: a challenging clinical-pathological correlation.
 

Author(s): Christian Wider, Dennis W Dickson, Katherine J Schweitzer, Daniel F Broderick, Zbigniew K Wszolek

Journal: J. Neurol.. 2009 May;256(5):839-42.

 

Last Updated: 19 May 2009

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Reviews from the PubMed Database

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The terms "Familial idiopathic basal ganglia calcification" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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