Juvenile idiopathic arthritis

Common Name(s)

Juvenile idiopathic arthritis, Pediatric arthritis, JIA, Juvenile rheumatoid arthritis, JRA

Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA), is the most common form of arthritis in children ages 6 months to 17 years. JIA causes inflammation (redness, swelling, heat, pain) in one, or many, joints (areas of the body where two bones fit together). JIA is not the same as the adult type of arthritis. There are seven different types of JIA (see related conditions below).

JIA causes pain, stiffness, swelling, and redness most commonly in the knees and joints of hands and feet. The joint may not move fully (decreased range of motion). Symptoms are usually worse in the morning or after a nap. The symptoms may go away after a few months or be lifelong. Some types of JIA can affect other parts of the body, causing swollen lymph nodes, rashes and fever, eye inflammation and growth problems.

The cause of JIA is unknown (idiopathic). However, it is believed that both environmental and genetic factors play a role. JIA may be an autoimmune or autoinflammatory disease. Usually, our immune system protects us from illness and infection by attacking viruses, bacteria and other foreign bodies. Sometimes our immune system attacks its own healthy cells. Different parts of our immune system can go wrong causing either an autoimmune or an autoinflammatory response.

Girls are more likely to have JIA. Certain viruses may also increase a child’s risk. To diagnose this condition, your child’s doctor or specialist may perform a physical exam, blood tests and special imaging tests of your child’s joints (using X-ray, MRI and video imaging). Although there is no cure for JIA, there are treatments that help reduce pain and swelling. These treatments include medications, therapy, and possibly surgery. If your child has been diagnosed with JIA, talk with their doctor about the most current treatment options. Support groups are also a good source of information and will help connect you with other families.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile idiopathic arthritis" for support, advocacy or research.

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International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

Last Updated: 18 Sep 2014

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile idiopathic arthritis" for support, advocacy or research.

Logo
International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

http://www.ifautoimmunearthritis.org

Last Updated: 18 Sep 2014

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile idiopathic arthritis" returned 678 free, full-text research articles on human participants. First 3 results:

Health-related quality of life among Swedish children with Juvenile Idiopathic Arthritis: parent-child discrepancies, gender differences and comparison with a European cohort.
 

Author(s): Veronica Lundberg, Catharina Eriksson

Journal:

 

This study investigates gender differences in self-reports and between parent and child reports in Health-related Quality of Life (HRQOL), measured with disease-specific and generic instruments for chronic disease. Comparison of HRQOL results in this Juvenile Idiopathic Arthritis ...

Last Updated: 13 Apr 2017

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Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans.
 

Author(s): Yukiko Kimura, Sriharsha Grevich, Timothy Beukelman, Esi Morgan, Peter A Nigrovic, Kelly Mieszkalski, T Brent Graham, Maria Ibarra, Norman Ilowite, Marisa Klein-Gitelman, Karen Onel, Sampath Prahalad, Marilynn Punaro, Sarah Ringold, Dana Toib, Heather Van Mater, Jennifer E Weiss, Pamela F Weiss, Laura E Schanberg,

Journal:

 

To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans (CTPs) for systemic Juvenile Idiopathic Arthritis (JIA) using an observational registry.

Last Updated: 12 Apr 2017

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Radiographic damage in hands and wrists of patients with juvenile idiopathic arthritis after 29 years of disease duration.
 

Author(s): Anne M Selvaag, Eva Kirkhus, Lena Törnqvist, Vibke Lilleby, Hanne A Aulie, Berit Flatø

Journal:

 

There are few studies on radiographic outcome after long-term disease duration in juvenile idiopathic arthritis (JIA). We wanted to evaluate 29-year radiographic outcome in hands/wrists and predictors of damage in patients with long-term active JIA.

Last Updated: 12 Apr 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile idiopathic arthritis" returned 95 free, full-text review articles on human participants. First 3 results:

A better understanding of juvenile idiopathic arthritis with classification criteria.
 

Author(s): Shinji Akioka

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2016 ;39(6):513-521.

 

  Juvenile idiopathic arthritis, JIA, is a novel rheumatic disease in childhood introduced by the International League of Associations for Rheumatology. It is defined as a chronic, inflammatory disorder of unknown etiology, which is classified into seven categories; systemic-onset ...

Last Updated: 4 Jan 2017

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The human microbiome and juvenile idiopathic arthritis.
 

Author(s): Anouk Verwoerd, Nienke M Ter Haar, Sytze de Roock, Sebastiaan J Vastert, Debby Bogaert

Journal:

 

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in childhood. The pathogenesis of JIA is thought to be the result of a combination of host genetic and environmental triggers. However, the precise factors that determine one's susceptibility to JIA remain to ...

Last Updated: 21 Sep 2016

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Gut microbiota-host interactions and juvenile idiopathic arthritis.
 

Author(s): Miika Arvonen, Lillemor Berntson, Tytti Pokka, Tuomo J Karttunen, Paula Vähäsalo, Matthew L Stoll

Journal:

 

Juvenile idiopathic arthritis is the most common form of chronic arthritis in children. There is mounting evidence that the microbiota may influence the disease.

Last Updated: 25 Jul 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pharmacovigilance in Juvenile Idiopathic Arthritis Patients Treated With Biologic Agents and/or Methotrexate
 

Status: Recruiting

Condition Summary: Juvenile Idiopathic Arthritis

 

Last Updated: 29 Feb 2016

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Massage Therapy in Juvenile Idiopathic Arthritis
 

Status: Recruiting

Condition Summary: Juvenile Idiopathic Arthritis

 

Last Updated: 12 Sep 2016

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