Hypoaldosteronism

Common Name(s)

Hypoaldosteronism

Hypoaldosteronism is a condition characterized by the shortage (deficiency) or impaired function of a hormone called aldosterone. Hypoaldosteronism may be described as hyporeninemic or hyperreninemic depending on renin levels. Hyporeninemic hypoaldosteronism occurs when there is decreased production of aldosterone due to decreased production of renin . Affected individuals typically have kidney (renal) disease due to various conditions, such as diabetes, interstitial nephritis, or multiple myeloma. Hyperreninemic hypoaldosteronism occurs when there is a problem with the production of aldosterone, but renin is produced normally by the kidneys. Common causes of this form of hypoaldosteronism are medications (ACE inhibitors), lead poisoning, severe illness, and aldosterone enzyme defects.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoaldosteronism" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoaldosteronism" returned 29 free, full-text research articles on human participants. First 3 results:

Hyporeninaemic hypoaldosteronism associated with membranous nephropathy: new hypotheses with regard to sodium retention in patients with proteinuria.
 

Author(s): Borja Quiroga, Soledad García de Vinuesa, Marian Goicoechea, José Luño

Journal: Nefrologia. 2013 ;33(3):428-9.

 

Last Updated: 28 May 2013

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Maternally-inherited diabetes with deafness (MIDD) and hyporeninemic hypoaldosteronism.
 

Author(s): Patricia B Mory, Marcia C dos Santos, Claudio E Kater, Regina S Moisés

Journal: Arq Bras Endocrinol Metabol. 2012 Nov;56(8):574-7.

 

Maternally-inherited diabetes with deafness (MIDD) is a rare form of monogenic diabetes that results, in most cases, from an A-to-G transition at position 3243 of mitochondrial DNA (m.3243A>G) in the mitochondrial-encoded tRNA leucine (UUA/G) gene. As the name suggests, this condition ...

Last Updated: 8 Jan 2013

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Life threatening hyperkalemia in a neonate with pseudo-hypoaldosteronism.
 

Author(s): Shehla Choudhry, Yawar Najam

Journal: J Pak Med Assoc. 2012 Mar;62(3):287-8.

 

Pseudohypoaldosteronism type 1 is a rare disorder characterized by renal resistance to aldosterone which may present with a salt wasting crisis in infancy. We report a neonate with hyponatremia, severe dehydration and refractory life threatening hyperkalemia who was treated with dietary ...

Last Updated: 5 Jul 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoaldosteronism" returned 2 free, full-text review articles on human participants. First 3 results:

Molecular genetic study in two patients with congenital hypoaldosteronism (types I and II) in relation to previously published hormonal studies.
 

Author(s): M Peter, K Bünger, S L Drop, W G Sippell

Journal: Eur. J. Endocrinol.. 1998 Jul;139(1):96-100.

 

We performed a molecular genetic study in two patients with congenital hypoaldosteronism. An original study of these patients was published in this Journal in 1982. Both index cases, a girl (patient 1) and a boy (patient 2). presented with salt-wasting and failure to thrive in the ...

Last Updated: 4 Sep 1998

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Primary acquired hypoaldosteronism.
 

Author(s): J P Kokko

Journal: Kidney Int.. 1985 Apr;27(4):690-702.

 

Last Updated: 22 Aug 1985

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Adrenal Function After Living Kidney Donation
 

Status: Recruiting

Condition Summary: Addison Disease; Hypoaldosteronism

 

Last Updated: 17 Apr 2007

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