Wolff Parkinson White syndrome

Common Name(s)

Wolff Parkinson White syndrome, Wolff-Parkinson-White pattern, Wolff-Parkinson-White Syndrome, Ventricular familial preexcitation syndrome

Wolff-Parkinson-White syndrome is a condition characterized by a disruption of the heart's normal rhythm (arrhythmia). People with this condition are born with a heart abnormality that can disrupt the coordinated movement of electrical signals through the heart.  This abnormaility leads to an abnormally fast heartbeat (tachycardia) and other arrhythmias. In most cases, the cause of Wolff-Parkinson-White syndrome is unknown. A small percentage of cases are caused by mutations in the PRKAG2 gene. These cases appear to be inherited in an autosomal dominant manner.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wolff Parkinson White syndrome" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

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SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmias and to provide education and support to families and the medical community.

http://www.StopSADS.org

Last Updated: 10 Dec 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wolff Parkinson White syndrome" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 30 Oct 2012

View Details
SADS (Sudden Arrhythmia Death Syndromes) Foundation

Our mission is to save the lives of young people who are genetically predisposed to sudden death due to cardiac arrhythmias and to provide education and support to families and the medical community.

http://www.StopSADS.org

Last Updated: 10 Dec 2012

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wolff Parkinson White syndrome" returned 177 free, full-text research articles on human participants. First 3 results:

[Atrial fibrillation in patient with concealed Wolff-Parkinson-White syndrome].
 

Author(s): Beata Sredniawa, Katarzyna Mitręga, Oskar Kowalski, Radosław Lenarczyk, Sławomir Pluta, Agata Musialik-Łydka, Zbigniew Kalarus

Journal: Kardiol Pol. 2013 ;71(11):1204-6.

 

We present a case of 33-year-old woman suffered from palpitations and syncope. ECG was normal at the rest and showed irregular tachycardia with wide QRS complex (HR > 300/min) during the effort. The patient was admitted to our department in order to perform detailed diagnostics and ...

Last Updated: 3 Dec 2013

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[Atypical form of tako-tsubo cardiomyopathy in a patient with atrial fibrillation in Wolff-Parkinson-White syndrome complicated with ventricular fibrillation: the diagnostic problems].
 

Author(s): Piotr Kukla, Sebastian Stec, Dariusz Karbarz, Bożena Wrzosek, Marek Jastrzębski, Maciej Kluczewski, Wojciech Kurdzielewicz

Journal: Kardiol Pol. 2013 ;71(8):864-8.

 

Atypical form of tako-tsubo cardiomyopathy (TTC) is associated with regional wall motion abnormalities in basal and/or middle segments or only middle segments with sparing of apical segments or apical and basal segments. We described a case of47-year-old female with atypical form ...

Last Updated: 19 Sep 2013

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Electroversion in treatment of arrhythmia in a patient with Wolff-Parkinson-White syndrome and cervical spinal cord injury.
 

Author(s): Peng Shen, Ru-Bin Luo, Si-Yu Cai, Mao Zhang

Journal: Chin. J. Traumatol.. 2013 ;16(3):176-7.

 

We report electroversion in treatment of atrial fibrillation (AF) and atrioventricular nodal reentry tachycardia (AVNRT) in a patient with Wolff-Parkinson-White syndrome and cervical spinal cord injury. At first, the patient sustained respiratory failure and weak cough reflex, thereafter ...

Last Updated: 5 Jun 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wolff Parkinson White syndrome" returned 9 free, full-text review articles on human participants. First 3 results:

Asymptomatic Wolff-Parkinson-White syndrome: incidental ECG diagnosis and a review of literature regarding current treatment.
 

Author(s): Alexander Liu, Pawan Pusalkar

Journal:

 

A 19-year-old male presented with periorbital cellulitis responsive to intravenous antibiotics. A routine ECG on admission showed slurred upstroke of the QRS complexes consistent with Wolff-Parkinson-White syndrome (WPW). He has never experienced any cardiac-related symptoms. Once ...

Last Updated: 13 Jun 2012

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Mechanisms for the genesis of paroxysmal atrial fibrillation in the Wolff Parkinson-White syndrome: intrinsic atrial muscle vulnerability vs. electrophysiological properties of the accessory pathway.
 

Author(s): Osmar Antonio Centurión, Akihiko Shimizu, Shojiro Isomoto, Atsushi Konoe

Journal: Europace. 2008 Mar;10(3):294-302.

 

Paroxysmal atrial fibrillation (PAF) develops in up to one-third of patients with the Wolff Parkinson-White syndrome (WPW). The reason for this high incidence of PAF in the WPW syndrome is not yet clearly understood. When PAF appears in patients with WPW syndrome who have anterograde ...

Last Updated: 29 Feb 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.