Wilms' tumor

Common Name(s)

Wilms' tumor, Wilm's Tumor

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wilms' tumor" for support, advocacy or research.

International WAGR Syndrome Association

Our mission is to promote international knowledge and awareness of WAGR syndrome and its complications and treatments, to stimulate research and to reach out to those affected by WAGR syndrome in an effort to improve their lives.

Last Updated: 12 Dec 2012

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Trisomy 18 Foundation

The Trisomy 18 Foundation (T18F) is the leading national organization devoted exclusively to improving outcomes for Trisomy 18 families in the United States. Committed to the support of medical research in finding effective treatments and preventions for Trisomy 18. The T18F also educates patient families and physicians about prevention, diagnosis and the treatment of Trisomy 18. The T18F is an active advocate for the Trisomy 18 community, helping to raise awareness of this disease and the need for treatments. The T18F's website is the premier source for educating the public about Trisomy 18 and impacted families..

Last Updated: 29 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wilms' tumor" for support, advocacy or research.

International WAGR Syndrome Association

Our mission is to promote international knowledge and awareness of WAGR syndrome and its complications and treatments, to stimulate research and to reach out to those affected by WAGR syndrome in an effort to improve their lives.

http://www.wagr.org

Last Updated: 12 Dec 2012

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Trisomy 18 Foundation

The Trisomy 18 Foundation (T18F) is the leading national organization devoted exclusively to improving outcomes for Trisomy 18 families in the United States. Committed to the support of medical research in finding effective treatments and preventions for Trisomy 18. The T18F also educates patient families and physicians about prevention, diagnosis and the treatment of Trisomy 18. The T18F is an active advocate for the Trisomy 18 community, helping to raise awareness of this disease and the need for treatments. The T18F's website is the premier source for educating the public about Trisomy 18 and impacted families..

http://www.trisomy18.org

Last Updated: 29 Apr 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wilms' tumor" returned 239 free, full-text research articles on human participants. First 3 results:

Wilms' tumor suppressor gene mutations in girls with sporadic isolated steroid-resistant nephrotic syndrome.
 

Author(s): Y H Yang, F Zhao, D N Feng, J J Wang, C F Wang, J Huang, X J Nie, G Z Xia, G M Chen, Z H Yu

Journal:

 

Mutations in the Wilms' tumor suppressor gene (WT1) can lead to syndromic forms of steroid-resistant nephrotic syndrome (SRNS) such as Denys-Drash or Frasier syndrome and can cause isolated SRNS. A mutation within WT1 is a frequent cause of sporadic isolated SRNS in girls. In a worldwide ...

Last Updated: 16 Dec 2013

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[Relationship between mRNA expression and promoter methylation status of p73 gene in peripheral blood among children with Wilms' tumor].
 

Author(s): Dong-Jian Song, Li-Fang Yue, Da Zhang, He-Ying Yang, Yu-Xia Fan, Ming Yue, Hang Pei, Jia-Xiang Wang

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2013 Aug;15(8):638-43.

 

To investigate the mRNA expression and promoter methylation status of p73 gene in the peripheral blood of children with Wilms' tumor (WT), and their relationship.

Last Updated: 22 Aug 2013

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Morphoproteomic profiling of the mammalian target of rapamycin (mTOR) signaling pathway in desmoplastic small round cell tumor (EWS/WT1), Ewing's sarcoma (EWS/FLI1) and Wilms' tumor(WT1).
 

Author(s): Vivek Subbiah, Robert E Brown, Yunyun Jiang, Jamie Buryanek, Andrea Hayes-Jordan, Razelle Kurzrock, Pete M Anderson

Journal:

 

Desmoplastic small round cell tumor (DSRCT) is a rare sarcoma in adolescents and young adults. The hallmark of this disease is a EWS-WT1 translocation resulting from apposition of the Ewing's sarcoma (EWS) gene with the Wilms' tumor (WT1) gene. We performed morphoproteomic profiling ...

Last Updated: 7 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wilms' tumor" returned 13 free, full-text review articles on human participants. First 3 results:

Botryoid Wilms' tumor: a case report and review of the literature.
 

Author(s): Guofeng Xu, Jimeng Hu, Yeming Wu, Yongtao Xiao, Maosheng Xu

Journal:

 

Here, we report a new case of botryoid Wilms' tumor, a 4-year-old boy, who was referred to us with a chief complaint of dysuria and gross hematuria. The computed tomography and radical nephroureterectomy showed that a botryoid sarcoma-like appearance occupied the right renal pelvis ...

Last Updated: 23 May 2013

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Active specific immunotherapy targeting the Wilms' tumor protein 1 (WT1) for patients with hematological malignancies and solid tumors: lessons from early clinical trials.
 

Author(s): Ann Van Driessche, Zwi N Berneman, Viggo F I Van Tendeloo

Journal: Oncologist. 2012 ;17(2):250-9.

 

There is a growing body of evidence that Wilms' tumor protein 1 (WT1) is a promising tumor antigen for the development of a novel class of universal cancer vaccines. Recently, in a National Cancer Institute prioritization project, WT1 was ranked first in a list of 75 cancer antigens. ...

Last Updated: 27 Feb 2012

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WT1 (Wilms' tumor gene 1): biology and cancer immunotherapy.
 

Author(s): Haruo Sugiyama

Journal: Jpn. J. Clin. Oncol.. 2010 May;40(5):377-87.

 

Wilms' tumor gene WT1 encodes a transcription factor and plays an important role in cell growth and differentiation. The WT1 gene is highly expressed in leukemia and various types of solid tumors, whereas WT1 is a tumor marker convenient for the detection of minimal residual disease ...

Last Updated: 4 May 2010

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gene Expression Profiles to Categorize Wilms Tumors
 

Status: Recruiting

Condition Summary: Recurrent Wilms Tumor and Other Childhood Kidney Tumors; Stage I Wilms Tumor; Stage II Wilms Tumor; Stage III Wilms Tumor; Stage IV Wilms Tumor; Stage V Wilms Tumor

 

Last Updated: 19 Feb 2014

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Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor
 

Status: Recruiting

Condition Summary: Clear Cell Sarcoma of the Kidney; Recurrent Wilms Tumor and Other Childhood Kidney Tumors; Rhabdoid Tumor of the Kidney; Stage I Wilms Tumor; Stage II Wilms Tumor; Stage III Wilms Tumor; Stage IV Wilms Tumor; Stage V Wilms Tumor

 

Last Updated: 8 Jul 2013

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Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
 

Status: Recruiting

Condition Summary: Diffuse Hyperplastic Perilobar Nephroblastomatosis; Stage I Wilms Tumor; Stage II Wilms Tumor; Stage III Wilms Tumor; Stage IV Wilms Tumor; Stage V Wilms Tumor

 

Last Updated: 1 Apr 2014

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