Wegener's granulomatosis

Common Name(s)

Wegener's granulomatosis

Wegener's granulomatosis is a type of vasculitis, or inflammation of the blood vessels. This limits the flow of blood to important organs, causing damage. It can affect any organ, but it mainly affects the sinuses, nose, trachea (windpipe), lungs and kidneys. Symptoms can vary in nature and severity, and may include sinus pain; discolored or bloody fluid from the nose; nasal ulcers; constant runny nose (rhinorrhea); joint pain; weakness; tiredness; and/or skin lesions. The cause of Wegener's granulomatosis is unknown. Early treatment is important. Most people improve with medicines to slow or stop the inflammation.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wegener's granulomatosis" for support, advocacy or research.

stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Wegener's granulomatosis" for support, advocacy or research.

stopcaidnow.org

Our mission is simple-Educate, Provide Awareness, and Fund Researchers who are committed to finding a cure. StopCAIDnow(501c3) is focused on providing tools to better educate Doctor’s and the community on AutoInflammatory diseases. There is a need for an understanding of these diseases so proper diagnosis can be made, and treatment can be started. This will help alleviate the inflammation process, 7 the pain that comes with it. Proper diagnosis is urgent for the prognosis of these diseases. If left untreated damage to the tissues, organs & vision(for some) will not only be irreversible but devastating

http://www.stopcaidnow.org

Last Updated: 5 Mar 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Wegener's granulomatosis" returned 523 free, full-text research articles on human participants. First 3 results:

Parotitis as the presenting symptom of Wegener's granulomatosis: case report and meta-analysis.
 

Author(s): Ilan Green, Martine Szyper-Kravitz, Yehuda Shoenfeld

Journal: Isr. Med. Assoc. J.. 2013 Mar;15(3):188-92.

 

Last Updated: 13 May 2013

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Parotid gland involvement as initial presentation of Wegener's granulomatosis: a diagnostic pitfall.
 

Author(s): Irina Kenis, Tania Zahavi, Ze'ev Korzets

Journal: Isr. Med. Assoc. J.. 2013 Mar;15(3):186-7.

 

Last Updated: 13 May 2013

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Wegener's granulomatosis and the salivary glands.
 

Author(s): Oded Nahlieli

Journal: Isr. Med. Assoc. J.. 2013 Mar;15(3):178-9.

 

Last Updated: 13 May 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Wegener's granulomatosis" returned 37 free, full-text review articles on human participants. First 3 results:

[Wegener's granulomatosis].
 

Author(s): Klára Gadó, László Z Szabó, László Csákó, Gyula Domján

Journal: Orv Hetil. 2013 Jul;154(28):1083-95.

 

Wegener's granulomatosis is a necrotizing inflammation of small and medium size vessels with granuloma formation. It is a very heterogeneous disease in respect of severity and clinical manifestation. While it can be a rapidly progressive disease with fatal ending, there are forms ...

Last Updated: 9 Jul 2013

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Panhypopituitarism due to Wegener's granulomatosis.
 

Author(s): Silvina G Santoro, Alberto H Guida, Alejandra E Furioso, Patricia Glikman, Amelia S Rogozinski

Journal: Arq Bras Endocrinol Metabol. 2011 Oct;55(7):481-5.

 

Wegener's granulomatosis (WG) is a multi-system necrotizing granulomatous vasculitis which classically affects the upper respiratory tract, lungs and kidneys. Pituitary participation has been described in 24 patients in the literature to date. The aim of this article is to report ...

Last Updated: 7 Dec 2011

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Cyclophosphamide as induction therapy for Wegener's granulomatosis and microscopic polyangiitis.
 

Author(s): C A Langford

Journal: Clin. Exp. Immunol.. 2011 May;164 Suppl 1():31-4.

 

The introduction of cyclophosphamide (CyP) as a treatment for Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) has been among the most significant contributions in vasculitis. Prior to the introduction of CyP, WG was a uniformly fatal disease, with mortality occurring ...

Last Updated: 30 Mar 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's)
 

Status: Not yet recruiting

Condition Summary: Granulomatosis With Polyangiitis (Wegener's); Granulomatosis With Polyangiitis; Wegener's Granulomatosis; ANCA-Associated Vasculitis

 

Last Updated: 4 Apr 2014

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Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis)
 

Status: Recruiting

Condition Summary: Granulomatosis With Polyangiitis

 

Last Updated: 22 May 2013

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The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach
 

Status: Recruiting

Condition Summary: Granulomatosis With Polyangiitis; Wegener Granulomatosis; Vasculitis

 

Last Updated: 17 Feb 2014

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