Tylosis

Common Name(s)

Tylosis, Palmoplantar keratoderma, nonepidermolytic, focal

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Tylosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Tylosis" returned 10 free, full-text research articles on human participants. First 3 results:

RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome.
 

Author(s): Diana C Blaydon, Sarah L Etheridge, Janet M Risk, Hans-Christian Hennies, Laura J Gay, Rebecca Carroll, Vincent Plagnol, Fiona E McRonald, Howard P Stevens, Nigel K Spurr, D Timothy Bishop, Anthony Ellis, Janusz Jankowski, John K Field, Irene M Leigh, Andrew P South, David P Kelsell

Journal: Am. J. Hum. Genet.. 2012 Feb;90(2):340-6.

 

Tylosis esophageal cancer (TOC) is an autosomal-dominant syndrome characterized by palmoplantar keratoderma, oral precursor lesions, and a high lifetime risk of esophageal cancer. We have previously localized the TOC locus to a small genomic interval within chromosomal region 17q25. ...

Last Updated: 13 Feb 2012

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[Hereditary tylosis syndrome and esophagus cancer].
 

Author(s): Camila Alves de Souza, Allan da Costa Santos, Lennon da Costa Santos, Artur Leonel Carneiro

Journal: An Bras Dermatol. ;84(5):527-9.

 

Tylosis palmoplantaris is an autosomal dominant disorder characterized by hyperkeratosis of palms and soles. Lesions start during childhood and are more evident in areas of pressure. Familial tylosis palmoplantaris comprises two forms: epidermolytic and non-epidermolytic. Patients ...

Last Updated: 25 Jan 2010

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Down-regulation of the cytoglobin gene, located on 17q25, in tylosis with oesophageal cancer (TOC): evidence for trans-allele repression.
 

Author(s): Fiona E McRonald, Triantafillos Liloglou, George Xinarianos, Laura Hill, Lynn Rowbottom, Joanne E Langan, Anthony Ellis, Joan M Shaw, John K Field, Janet M Risk

Journal: Hum. Mol. Genet.. 2006 Apr;15(8):1271-7.

 

Tylosis (focal non-epidermolytic palmoplantar keratoderma) is an autosomal dominant skin disorder that is associated with the early onset of squamous cell oesophageal cancer (SCOC) in three families. Our previous linkage and haplotype analyses have mapped the tylosis with oesophageal ...

Last Updated: 3 Apr 2006

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Tylosis" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy Study & Safety Evaluation of SR-T100 Gel in Actinic Keratosis Treatment
 

Status: Recruiting

Condition Summary: Actinic Keratosis

 

Last Updated: 23 Apr 2014

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Last Updated: 21 Jun 2011

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Effect of Nigella Sativa in the Treatment of Palmer Arsenical Keratosis
 

Status: Recruiting

Condition Summary: Arsenical Keratosis

 

Last Updated: 24 Apr 2013

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