Transposition of great arteries

Common Name(s)

Transposition of great arteries

Transposition of the great arteries (TGA) is a type of congenital heart defect in which there is a reversal of the normal connections of the aorta and the pulmonary artery with the heart. The aorta and pulmonary artery are reversed, which causes oxygen-poor blood to be circulated to the body and oxygen-rich blood to be circulated between the lungs and the heart, rather than to the body. Symptoms are apparent at birth and include great difficulty breathing and severe cyanosis (a bluish discoloration of the skin). The exact cause of TGA in most cases is unknown. Surgery is done to correct the abnormality during the first few days of life.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transposition of great arteries" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transposition of great arteries" returned 0 free, full-text research articles on human participants.

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The terms "Transposition of great arteries" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic Resonance
 

Status: Recruiting

Condition Summary: Coarctation of the Aorta; Tetralogy of Fallot; Transposition of the Great Arteries

 

Last Updated: 10 Jun 2014

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A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and Pharmacokinetics
 

Status: Recruiting

Condition Summary: Transposition of the Great Arteries; Tetralogy of Fallot; Ventricular Septal Defect

 

Last Updated: 4 Apr 2014

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Oxygen Consumption-based Assessments of Hemodynamics in Neonates Following Congenital Heart Surgery (Oxy-CAHN Study)
 

Status: Recruiting

Condition Summary: Transposition of the Great Vessels; Hypoplastic Left Heart Syndrome; Oxygen Consumption Based Assessment of Hemodynamics

 

Last Updated: 3 Jul 2014

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